TB Research

Eradicating Pulmonary <i>Mycobacterium abscessus</i>: The Promise of Dual β-Lactam Therapy

Bayan Alahmdi, Khalid M Dousa, Sebastian G. Kurz, Andrew Kaufman, Robert A. Bonomo, Sarah Taimur

Open Forum Infectious Diseases · 2023-06

Abstract

Abstract Macrolide resistance has rendered the treatment of Mycobacterium abscessus extremely difficult and is fueling a crisis. Recently, there has been dramatically increased incidence of infections by M abscessus. Select dual β-lactam combinations have shown promising in vitro results. Herein, we present a patient whose M abscessus infection cured using dual β-lactams as part of multidrug regimen.

MeSH terms

  • Mycobacterium abscessus
  • Medicine
  • Regimen
  • Microbiology
  • Combination therapy
  • Beta-lactam
  • Mycobacterium avium complex
  • Dual (grammatical number)
  • Antibiotics