A complex case of diagnostics of generalized tuberculosis, long-term imitation of sarcoidosis

The aim of the study. To analyze a clinical case and demonstrate the most rational research methods for the differential diagnosis of tuberculosis and sarcoidosis. Ma-terials and methods of research. The article presents an analysis of a complex clinical case of generalized tuber-culosis, which for a long time could not be verified due to the lack of bacterial excretion and the similarity of clinical and radiological manifestations with those of respiratory sarcoidosis. Results. The patient’s disease developed and proceeded asymptomatically, it was revealed during pre-ventive fluorography of the UCP. Later, the young man was periodically examined in various medical institutions for about 18 months, tuberculosis was not diagnosed, the disease proceeded under the “mask” of sarcoidosis. This situation led to the generalization of a specific infection. At the same time, even after the start of a permanent specialized examination using modern diagnostic meth-ods, it took almost 4 months starting from the diagnoses of “lacunar angina”, “community-acquired pneumonia”, “sarcoidosis of the respiratory organs stage 2 in combi-nation with lytic destruction of the 7th thoracic vertebra”, “lympho proliferative disease of unclear etiology”, the state of “differential diagnosis between sarcoidosis, tuber-culosis, lymphoproliferative disease” before the diagnosis of “generalized tuberculosis” was confirmed histological-ly. Conclusion. Biopsy methods with subsequent histo-logical verification of the diagnosis played a decisive role in the detection of the disease. Considering the above, it is advisable for all patients with suspected sarcoidosis who are admitted to medical institutions, regardless of the stage of the process and the results of the previous exam-ination, to consult a phthisiologist, to perform diagnosis minimum before this to exclude active tuberculosis.