Isoniazid-induced hepatic injury: a case report and its mechanism of liver injury

One of the most frequently used anti-tubercular medications, isoniazid, commonly referred to as Isonicotinic acid hydrazide, is an antibiotic for the treatment of tuberculosis (TB). A prodrug called isoniazid inhibits mycobacterial cellular structures from developing. Isoniazid activation necessitates the presence of KatG, a bacterial catalase-peroxidase enzyme present in Mycobacterium tuberculosis. Since the liver plays a significant role in the metabolism and detoxification of drugs, it is sub