TB Research

An Evaluation of The Diagnostic Value of Sputum Smears Microscopy and Pcr Relative to Sputum Culture in The Diagnosis of Pulmonary Tuberculosis: A Systematic Review and Meta-Analysis in Iran

Shoboo Rahmati, Abbas Bahrampour, Mahshid Nasehi, Ali Mirzazadeh, Hosna Ghaderi, Armita Shahesmaeili

Medical Journal of the Islamic Republic of Iran · 2022-06

Abstract

Background: Tuberculosis is one of the oldest known diseases in humans, and early detection of tuberculosis is one of the main measures to decrease the spread of tuberculosis. In many parts of the world, including Iran, the diagnosis of tuberculosis is based on the detection of acid-fast bacillus in sputum smear microscopy and PCR. this study aimed to synthesize evidence on the diagnostic accuracy of sputum smear and PCR compared to sputum culture for the diagnosis of PT in Iranian patients.

MeSH terms

  • Sputum
  • Medicine
  • Tuberculosis
  • Meta-analysis
  • Internal medicine
  • Gold standard (test)
  • Systematic review
  • Mycobacterium tuberculosis
  • Population
  • Gastroenterology
  • Pathology