Comparative Study of Cartridge Based Nucleotide Amplification Test (CBNAAT) Versus Sputum Microscopy for the Diagnosis of Pulmonary Tuberculosis in People living with HIV and its Correlation with CD4 Count

Background: Diagnosis of tuberculosis is a challenge on its own, more so in HIV-infected individuals. The Xpert MTB/RIF assay has recently replaced sputum microscopy as the investigation of choice in People living with HIV (PLHIV). The present study aims to compare two methods for the diagnosis of TB in PLHIV: Microscopy, and Xpert MTB/RIF. and to compare with CD4 count Objective of the Study 1. To compare between efficacy of CBNAAT and sputum microscopy in detection of pulmonary tuberculosis in HIV patients.