TB Research

EVALUATION OF THE REACTIVITY OF THE ORGANISM DURING COMBINED THERAPY IN PATIENTS WITH TUBERCULOSIS BY CELL PARAMETERS AND BIOCHEMICAL INDICATORS

A. A. Mazurova, K. M. Shpadaruk

SAKHAROV READINGS 2022: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2 · 2022-05

Abstract

In the course of the study, an assessment was made of the reactivity of the organism of patients suffering from tuberculosis, according to cellular indicators of peripheral blood and integral indices of homeostasis (leukocyte index of intoxication according to Kalf-Kalif (LII), index of the ratio of neutrophils to lymphocytes (NIL), index of the ratio of neutrophils and monocytes (IRNM), the index of the ratio of lymphocytes and eosinophils (IRLE), the index of the ratio of lymphocytes to the erythrocyte sedimentation rate (IRSOE) for therapy.As a result of the study, we found that during therapy in patients with tuberculosis, the erythrocyte population is the most sensitive parameters to the treatment. Also, the most sensitive and highly informative are integral indicators: the index of the ratio of neutrophils to lymphocytes, the index of the ratio of lymphocytes and eosinophils and the index of the ratio of neutrophils and monocytes.

MeSH terms

  • Tuberculosis
  • Immunology
  • Erythrocyte sedimentation rate
  • Lymphocyte
  • Index (typography)
  • Peripheral blood
  • Population
  • Medicine
  • Internal medicine