TB Research

The Association between Circulating microRNAs and the Risk of Active Disease Development from Latent Tuberculosis Infection: a Nested Case-Control Study

Henan Xin, Xuefang Cao, Ying Du, Jiaoxia Yan, Rui He, Zisen Liu, Haoran Zhang, Yijun He, et al. (19 authors)

Microbiology Spectrum · 2022-04

Abstract

Approximately a quarter of the world population are infected with M. tuberculosis and about 5% to 10% of these might develop active disease in their lifetime. Preventive treatment could effectively protect individuals at a high risk of developing active disease from LTBI, and is regarded as a critical component of End TB Strategies.

MeSH terms

  • Tuberculosis
  • Nested case-control study
  • Association (psychology)
  • Disease
  • Latent tuberculosis
  • Case-control study
  • Active tuberculosis
  • Medicine
  • microRNA
  • Immunology
  • Biology