TB Research

Assessment of multidrug-resistant tuberculosis patient's skin drug reaction in Zanzibar: A certain causal relationship with Clofazimine

Mohamed SA, Mshana JO, Abubakar K, Juma AH, Mussa IA, Hamad MF, Juma JK, Khalid FJ, et al. (9 authors)

International journal of mycobacteriology · 2022-01

Abstract

Drug-resistant tuberculosis (DR-TB) is a serious public health of concern. We present the management of multidrug-resistant (MDR)-TB with skin reaction in Zanzibar in a patient who had prior exposure to anti-TB drugs. The reaction developed 4 months later, following MDR-TB treatment, stopped when the drug was withdrawn, and reappeared when reintroduced. Close monitoring is important in managing DR-TB cases, and an active DR-TB safety, monitoring, and management is required to detect, monitor, and manage adverse events timely.

MeSH terms

  • Humans
  • Mycobacterium tuberculosis
  • Tuberculosis, Multidrug-Resistant
  • Clofazimine
  • Antitubercular Agents
  • Tanzania
  • Drug-Related Side Effects and Adverse Reactions