Author response: De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis
Thomas Laval, Laura Pedró-Cos, Wladimir Malaga, Laure Guenin‐Macé, Alexandre Pawlik, Véronique Mayau, Hanane Yahia‐Cherbal, Océane Delos, et al. (12 authors)
Abstract
Infection with Mycobacterium tuberculosis triggers de novo synthesis of polyunsaturated fatty acids by host macrophages, which promote their antimicrobial responses but feed the intracellular pathogen.
MeSH terms
- Myelopoiesis
- Polyunsaturated fatty acid
- Mycobacterium tuberculosis
- Biology
- Eicosanoid
- Intracellular
- Innate immune system
- Immune system
- Microbiology
- Intracellular parasite
- Arachidonic acid
- Biochemistry