Editor's evaluation: De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis
Bavesh D Kana
Abstract
Infection with Mycobacterium tuberculosis triggers de novo synthesis of polyunsaturated fatty acids by host macrophages, which promote their antimicrobial responses but feed the intracellular pathogen.
MeSH terms
- Polyunsaturated fatty acid
- Myelopoiesis
- Mycobacterium tuberculosis
- Biology
- Eicosanoid
- Intracellular
- Immune system
- Innate immune system
- Microbiology
- Intracellular parasite
- Biochemistry
- Arachidonic acid
- Immunology
- Cell biology