Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients
Acquah R, Mohr-Holland E, Daniels J, Furin J, Loveday M, Mudaly V, Reuter A
The Pediatric infectious disease journal · 2021-05
Abstract
This brief report presents a series of 5 pregnant women treated for rifampicin-resistant tuberculosis with the novel drugs bedaquiline, delamanid, and linezolid as part of an optimized backbone regimen and reviews the outcomes of the children born to them. Although the case series is small, all children had excellent birth outcomes suggesting pregnant women should not be denied access to novel therapies for RR-TB.
MeSH terms
- Humans
- Tuberculosis, Multidrug-Resistant
- Nitroimidazoles
- Oxazoles
- Antitubercular Agents
- Pregnancy Outcome
- Pregnancy
- Adult
- Child, Preschool
- Infant
- South Africa
- Female
- Young Adult
- Diarylquinolines
- Child Health
- Linezolid
- Infant Health
- Pregnant People