TB Research

Disseminated <i>Mycobacterium tuberculosis</i> following renal transplant: A case report

Mahmoud Sadeghi Haddad Zavareh, Mohammad Reza Hasanjani Roushan, Zeinab Mohseni Afshar, Masomeh Bayani, Soheil Ebrahimpour, Shahab Saeedi, Arefeh Babazadeh

Pneumologia · 2020-12

Abstract

Abstract Miliary tuberculosis (TB) presents a major challenge following a renal transplant in humans. In the current report, we described a patient with disseminated TB following renal transplantation. The article presents the case of a 38-year-old man who presented an 8-month history of fever, chills, sweating, low-back pain and significant weight loss. Chest radiography and computed tomography (CT) scan showed miliary nodules distributed in the two lungs. The transbronchial lung biopsy revealed a granulomatous reaction with caseous necrosis. Magnetic resonance imaging (MRI) of the brain found multiple tuberculomas. Also, MRI of the lumbosacral was indicative of a psoas abscess. Therefore, miliary pulmonary, cerebral and spinal TB was confirmed. The patient was started on an anti-TB regimen and paravertebral aspiration was also done. The patient’s condition improved considerably. In conclusion, this case report can remind us of the importance of maintaining a high clinical suspicion and performing a thorough workup to establish a timely diagnosis and treatment of miliary TB.

MeSH terms

  • Medicine
  • Miliary tuberculosis
  • Caseous necrosis
  • Chills
  • Tuberculosis
  • Magnetic resonance imaging
  • Radiology
  • Tuberculoma
  • Abscess
  • Surgery
  • Biopsy