TB Research

Novel 6-Month Treatment for Drug-Resistant Tuberculosis, United States

Connie A. Haley, Patricia Macias, Supriya Jasuja, Betsy A. Jones, Marie‐Claire Rowlinson, Roshni Jaimon, Pennelyn Onderko, Elaine Darnall, et al. (12 authors)

Emerging infectious diseases · 2020-11

Abstract

The US Food and Drug Administration approved a 6-month regimen of pretomanid, bedaquiline, and linezolid for extensively drug-resistant or multidrug-intolerant tuberculosis after a trial in South Africa demonstrated 90% effectiveness 6 months posttreatment. We report on a patient who completed the regimen using a lower linezolid dose.

MeSH terms

  • Bedaquiline
  • Linezolid
  • Regimen
  • Medicine
  • Tuberculosis
  • Drug
  • Extensively drug-resistant tuberculosis
  • Drug resistance
  • Food and drug administration
  • Internal medicine
  • Pharmacology