UNUSUAL PARADOXICAL RESPONSE OF TUBERCULOSIS MIMICKING LUNG MALIGNANCY, A CASE OF XDR TUBERCULOSIS

and Aims: WHO issued a recommendation for the use of standard 9-11 month Shorter Multidrug-Drug Resistant Tuberculosis regimen.It will impact the number of patients treated and improve obedience because of the shorter, low cost, and well tolerated.Sputum culture is an important examination in monitoring the response to MDR TB treatment, and several factors can predict a prolonged time to culture conversion.The aim of this study was to investigate the correlation of Body Mass Index with time to sputum conversion in patients treated with shorter MDR-TB regimen at Adam Malik Hospital from November 2017 to January 2019.Methods: A case series design with a total of 76 MDR pulmonary TB patients who underwent shorter regimen was performed.Samples were obtained from medical record in the pulmonary isolation inward and MDR TB polyclinic at Adam Malik Hospital, Indonesia.Data was analyzed descriptively to identify the trend of sputum conversion of the nine months treatment.Results: Out of all patients 68.4% were males and 31.6% were females.Majority are in 41-50 years old age group, with normal BMI 51.4%.Time of sputum conversion occurred in the second month of the treatment and those with normal weight experienced more sputum conversion than those underweight patients.Out of 76 patients, those with complete treatment was 47.4%, those who are cured 44.8%, dropped out 28.9%, failed 15.8%, exitus 9.2%, transferred 1.3%. Conclusion:In this study of Shorter Multi-Drug Resistant Tuberculosis Regimen, all cases with various BMI categories are converted on to negative on the second month of treatment.