Safety and Tolerability of Clofazimine in a Cohort of Children With Odontogenic Mycobacterium abscessus Infection
Felice C. Adler‐Shohet, Jasjit Singh, Delma Nieves, Negar Ashouri, M Tuan Tran, M Cathy Flores, Antonio Arrieta
Journal of the Pediatric Infectious Diseases Society · 2019-06
Abstract
Mycobacterium abscessus infections can be challenging to treat. Clofazimine has excellent in vitro activity against M abscessus, but reports of its use, particularly in children, have been limited. In this study, clofazimine was given to 27 children during an outbreak of odontogenic mycobacterial infections and seemed to be well tolerated as part of a multidrug regimen.
MeSH terms
- Clofazimine
- Medicine
- Mycobacterium abscessus
- Tolerability
- Regimen
- Mycobacterium Infections
- Nontuberculous mycobacteria
- Rifabutin
- Mycobacterium fortuitum
- Cohort
- Clarithromycin
- Microbiology
- Mycobacterium