Treatment Outcomes of Patients Switching From an Injectable Drug to Bedaquiline During Short Standardized Treatment for Multidrug-resistant Tuberculosis in Mozambique
Mathieu Bastard, Lucas Molfino, Claúdia Mutaquiha, Miriam Arago Galindo, Pereira Zindoga, Deise Vaz, Ivan Mahinça, Philipp du Cros, et al. (10 authors)
Clinical Infectious Diseases · 2019-03
Abstract
Bedaquiline was recommended by the World Health Organization as the preferred option in treatment of multidrug-resistant tuberculosis (MDR-TB) with long regimens. However, no recommendation was given for the short MDR-TB regimen. Data from our small cohort of patients who switched from injectable drug to bedaquiline suggest that a bedaquiline-based short regimen is effective and safe.
MeSH terms
- Bedaquiline
- Medicine
- Tuberculosis
- Multiple drug resistance
- Drug
- Culture conversion
- Drug resistance
- Drug resistant tuberculosis
- Tb treatment
- Intensive care medicine
- Pharmacology