MDR-TB- Clinical Profile of MDR-TB Cases at DR-TB Centre

The present study was carried at NKPSIMS , RC & LMH on patients admitted in one year from Dec 2012 to Nov 2013 after confirmation of being a Multidrug resistant tuberculosis (MDR-TB) case (i.e. resistant to Rifampicin or to both Isoniazid & Rifampicin).96 patients (69 males & 27 females) were registered, admitted and treated for MDR-TB/ XDR-TB and were thoroughly reviewed regarding age, sex, residence, socioeconomic status, symptomatology, duration of illness, prior regularity or irregularity in respect of treatment received, prior receipt of number of anti-TB regimens and comorbid illnesses and adverse drug reactions. Males outnumbered the females, residents of Nagpur district (urban and rural areas) were found to be more than other districts of Vidarbha region. One patient of Extra Pulmonary MDR-TB was registered and initiated on CAT-IV regimen and there was one confirmed case of XDR-TB who was admitted and investigated for auxilliary investigations and initiated on CAT-V regimen. This study reflects the case of "NKPS Nagpur Model" a PPP model which delivers to TB & MDR-TB patients and nutritional supplements as well. The unique feature of this model is that Public sector role is to provide human resources and free investigations with free drug delivery and the private sector provides specialist care to DR-TB patients along with infrastructure support. This approach has become known as the "NKPS Nagpur Model ". Early diagnosis, registration and initiation of Anti MDR-TB and XDR-TB regimens can prevent the dissemination and transmission of the deadly and dreadful resistant bacilli.