COMPARISON OF DEMOGRAPHIC, LABORATORY PARAMETERS AND CLINICAL OUTCOMES AMONG TUBERCULOSIS PATIENTS WITH AND WITHOUT HYPERTENSION IN KANPUR AT TERTIARY CARE TEACHING HOSPITAL

Background: Tuberculosis (TB) is a major global health problem and one of the top 10 causes of death worldwide. Aim: To compare the demographic characteristics, laboratory parameters and clinical outcomes of TB patients with and without hypertension (HTN) at a tertiary care teaching hospital. Methodology: A prospective cross-sectional study involving 220 patients divided into two groups with 95 patients from group I without HTN and 125 patients from group II with HTN. The study was conducted in the outpatient department of TB and chest medicine ward in a tertiary care teaching hospital. Results: The demographic data shows that males were affected. The economic status was similar in a group with Group I including 55%, 29.4% & 14.6% of subjects from poor, middle and rich economic status respectively and group II including 56.8%, 26.4% and 16.8% of subjects from poor, middle and rich economic status respectively. The study shows that alcohol consumption is a major risk factor in both groups. Chest X-ray, Mantoux test and sputum test was done almost for all subjects. Conclusion: From the present study we conclude that among selected demographic parameters and metabolic disorders were higher among patients with TB and HTN when compared with TB alone group. Smoking is the major risk factor-induced significant changes in functions of pulmonary and cavitary among both the group patients. The therapeutic goal was achieved for the group is attained faster when compared with the other group of patients, but both groups treatment was above 85% against the WHO statement. Adherence to therapeutic regimen was found to be satisfactory.