TB Research

Heat Inactivation Renders Sputum Safe and Preserves <i>Mycobacterium tuberculosis</i> RNA for Downstream Molecular Tests

Wilber Sabiiti, Khalide Azam, Ezembro Esmeraldo, Nilesh Bhatt, Andrea Rachow, Stephen H. Gillespie

Journal of Clinical Microbiology · 2019-02

Abstract

The World Health Organization End Tuberculosis (TB) strategy has called for the development of—and increased access to—effective tools for diagnosis and treatment of TB disease. Mycobacterium tuberculosis , the causative agent of TB, is categorized as a highly infectious agent.

MeSH terms

  • Sputum
  • Mycobacterium tuberculosis
  • Tuberculosis
  • Microbiology
  • RNA
  • Biology
  • Virology
  • Medicine