Showing 1–25 of 200 documents
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Kanjanaphan T
…igation of LTBI in healthcare personnel (HCPS) working with pediatric patients with active pulmonary TB and report the side effects of 12-week-isoniazid and rifapentine (3HP). Methods This contact investigation reviewed HCPS who were in close contact with pediatric pulmonary TB. …
Martinelli M, Giugliano FP, Strisciuglio C, Urbonas V, Serban DE, et al.
…accine-preventable diseases and opportunistic infections in pediatric inflammatory bowel disease (IBD) are increasingly recognized issues. The aims of this study were to evaluate vaccinations, immunization status, and consequent therapeutic management in children with IBD and to …
Tulane University
Pediatric tuberculosis (TB) continues to pose diagnostic challenges in low- and middle-income countries with high rates of TB disease, due to the well-described impact of paucibacillary disease in children, and current TB culture and polymerase-chain reaction tests are of limited…
Kapil Saharia
Background: The incidence of pediatric tuberculosis (TB) in North Carolina decreased from the mid 1990s to 200l. In 2002, the number of pediatric TB cases increased from 9 in 2001 to 32 in 2002, representing more than a 250% increase. Objective: To describe the epidemiology and c…
Meyer Children's Hospital IRCCS
…s were reported in 2020, of which 1 million occurred in the pediatric population. However, epidemiological data available on tuberculosis (TB) in pediatric age are extremely limited due to diagnostic challenges in this patient category. Furthermore, children are almost never incl…
Yoonsun Yoon, Joon‐sik Choi, Hanpum Yoon, Sun Young Cho, Yae‐Jean Kim
…reported. There have been few reports of TB exposure in the pediatric hematology-oncology ward. Methods A mother of a pediatric cancer patient was diagnosed with active TB with a cavity. Contact investigation was performed on patients, their parents, and healthcare workers who we…
Daniela Russo
…rculosis (TB) remains a major public health problem. In the pediatric population, the prevention and diagnosis of TB is considered a major challenge. For this reason, this scoping review will be conducted in order to systematically map the research carried out in this area and id…
Kim Y, Bae KS, Choi UY, Han SB, Kim JH
Background The treatment of pediatric patients with latent tuberculosis infection (LTBI) is a crucial TB control strategy. LTBI is not a reportable communicable disease, and data regarding LTBI treatment in pediatric patients in Korea are scarce. This study aimed to investigate t…
Money NM, Schroeder AR, Quinonez RA, Ho T, Marin JR, et al.
Importance Medical overuse is common in pediatrics and may lead to unnecessary care, resource use, and patient harm. Timely scrutiny of established and emerging practices can identify areas of overuse and empower clinicians to reconsider the balance of harms and benefits of the m…
Adusumelli Y, Tabatneck M, Sherman S, Lamb G, Sabharwal V, et al.
… to engaging in TB infection care is critical to preventing pediatric TB disease. We explored families' and clinicians' perspectives on pediatric TB infection diagnosis and care. Methods We conducted individual interviews and small group discussions with primary care and subspeci…
Jeffrey I. Campbell, Thomas J. Sandora, Jessica E. Haberer
…ts to eliminate TB by 2030. Identification and treatment of pediatric LTBI requires completion of a complex care cascade. While attention has been given to LTBI care cascades in adults, to date there has been no attempt to map literature on the pediatric LTBI care cascade. Facili…
Ananya S Willsraj, Suba Joice, Y Dishan, Blessed Singh, Ajin Chandran
…ials and methods: A cross-sectional study was done among 90 pediatric HHC (5–15 years) of 48 microbiologically confirmed pulmonary TB patients notified in Neyyattinkara TB unit from March 2021 to July 2022. Data were entered and analyzed using SPSS trial version 26. All qualitati…
Peck GM, Staat MA, Huang FS, Khalil N, Boyce C, et al.
…ad of tuberculosis and the progression to active disease in pediatric patients. As of 2017, the short course combination regimen of weekly isoniazid and rifapentine (3HP) administered by directly observed therapy (DOT) has replaced 9 months of isoniazid as the standard of treatme…
Patricia Comella-del-Barrio, José Luis Izquierdo-García, Ramón Campos‐Olivas, Clara M. Santiveri, Jesús Ruı́z-Cabello, et al.
…al scoring systems limited by the TB clinical presentation. Pediatric TB diagnosis research should be focused on new biomarkers from non-invasive and non-sputum-based samples. By metabolomics we can obtain a “fingerprint<i>”</i> of the metabolites presents in a biological sample,…
Campbell J, Sandora T, Haberer J
…ts to eliminate TB by 2030. Identification and treatment of pediatric LTBI requires completion of a complex care cascade. While attention has been given to LTBI care cascades in adults, to date there has been no attempt to map literature on the pediatric LTBI care cascade. Facili…
Surve S, Naukariya K, Shah I
…s been reported between 21 and 48%. The exact prevalence of pediatric LTBI in India is still not clear, however, as per few studies, the LTBI prevalence ranges around 40% and 22% in adolescent followed by under-5 population. Studies to fill in the research gap of scarcity of prev…
Anita Uka, Frédéric Méchaï, Daniela Maria Cirillo, Lorenzo Guglielmetti, Yousra Kherabi, et al.
Introduction Tuberculosis (TB) remains a leading cause of pediatric morbidity and mortality worldwide, with diagnostic and therapeutic challenges continuing to affect outcomes, including in high-income settings. The TBSure study investigated current practices in pediatric TB diag…
Gaensbauer J, Aiona K, Haas M, Reves R, Young J, et al.
…BI) to active disease. Therefore, regimens for treatment of pediatric LTBI must be not only efficacious but practical enough to overcome the unique childhood barriers to regimen adherence. Since 2012, a 4-month regimen of daily rifampin (4R) has been the standard recommendation f…
Özlem Tezol
Objectives: Pediatric tuberculosis is a major public health problem. Malnutrition characterized with wasting is prevalent among pediatric tuberculosis patients. We aimed to review pediatric tuberculosis cases by considering their nutrition manifestations. Materials and Methods: T…
Jeanine Diur Yav, Armand Mutwadi, Albert Kalonji, Fiston Ilunga Mbayo, Pacifique Kanku Wa Ilunga, et al.
… vulnerable group. In the Democratic Republic of the Congo, pediatric TB continues to be underdiagnosed and underreported, particularly in rural health zones such as Kabondo Dianda. **OBJECTIVE:** This study aimed to assess the knowledge, perceptions, and practices of guardians …
Gaensbauer J, Broadhurst R
…ests and broader application in non-sputum samples for both pediatric pulmonary and extrapulmonary tuberculosis. Finally, recent studies have provided solid evidence in support of shorter treatment courses for pediatric latent tuberculosis infection, such as 12 weeks of weekly is…
Ma HW, Lee HS, Ahn JY
…e target for reducing the infection rate. The management of pediatric LTBI is especially crucial because children can serve as a long-term source of infection upon developing active tuberculosis. Therefore, it is important to assess pediatric LTBI using contact investigation and …
Mase A, Ryan S, Mader G, Alvarez A, Armitige L, et al.
…ement of TB in children has not been described. We analyzed pediatric TB consultations performed across all RTMCCs in terms of question type, provider type, and setting. Methods The CDC medical consultation database was queried for consultations regarding patients ≤ 18 years prov…
Malhotra S, Dasgupta-Tsinikas S, Yumul J, Kaneta K, Lenz A, et al.
…aluate implementation of rifamycin-based regimens (RBR) for pediatric tuberculosis infection (TBI) treatment among 3 provider settings in a high-incidence county. Study design A multicenter, retrospective observational study was performed across 3 sites in Los Angeles County: an …
Nadia E Hoekstra, Mark E. Anderson, James Gaensbauer
…logy and risk factors informing current American Academy of Pediatrics (AAP) guidelines on screening for pediatric latent tuberculosis infection (LTBI) have evolved over the past decade. To improve pediatric LTBI screening efficiency, we sought to reevaluate characteristics assoc…