Showing 1–25 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
V. V. Sinkov, С. Н. Жданова, О. Б. Огарков, Е. Д. Савилов
Introduction. The spread of drug-resistant tuberculosis necessitates the implementation of novel analytical approaches for assessing epidemiological risks using wholegenome sequencing (WGS) data. Objective. To develop an Integrated Epidemiological Risk Index (IERI) that accounts …
Peiyu Xu, Shenni Liang, Andrew Hahn, Vivian Zhao, Wai Tung 'Jack' Lo, et al.
…forming public health strategies. However, existing genomic epidemiology simulators typically assume conditional independence among these processes: generating transmission trees independently of pathogen evolution, and then superimposing neutral mutations onto fixed genealogies …
Zongying Zhan, Tiancheng Xie, Tianshuo Zhao, Xiyu Zhang, Sihui Zhang, et al.
**OBJECTIVE:** To analyse temporal trends of respiratory infectious diseases (RIDs) in Baiyin City from 2014 to 2023, aiming to explore the epidemiological patterns of these diseases (tuberculosis, scarlet fever, pertussis, measles, influenza, mumps, varicella and rubella) and pr…
Carson J, Keeling M, Ribeca P, Didelot X
…nfluenza H7N7 in the Netherlands to reconstruct its spatial epidemiology. In both cases, we show that incorporating epidemiological data into the genomic analysis allows us to investigate the role of epidemiological properties in the spread of infectious diseases.
Jajou R, de Neeling A, van Hunen R, de Vries G, Schimmel H, et al.
Background Patients with Mycobacterium tuberculosis isolates sharing identical DNA fingerprint patterns can be epidemiologically linked. However, municipal health services in the Netherlands are able to confirm an epidemiological link in only around 23% of the patients with isola…
L.D. Todoriko, O.Ya. Pidverbetskyi, О.С. Шевченко, О.V. Pidverbetska
Military conflicts have a negative impact on the epidemiology of various diseases, among which tuberculosis is in the lead. The increased risk of TB morbidity and mortality associated with war has been observed since World Wars I and II, and several civil wars, among others. Sepa…
Goscé L, Tadesse AW, Foster N, van Kalmthout K, Rest JV, et al.
Background Digital adherence technologies (DATs) with associated differentiated care are potential tools to improve tuberculosis (TB) treatment outcomes and reduce associated costs for both patients and healthcare providers. However, the balance between epidemiological and econom…
П. А. Хромова, V. V. Sinkov, Е. Д. Савилов, О. Б. Огарков
Relevance . The article presents an example of using the method of integral assessment of the epidemiological situation of tuberculosis, which is applied to the main statistical criteria as a more accurate approach in assessing the manifestation of the epidemic process and identi…
Buenestado-Serrano S, Martínez-Lirola M, Dippenaar A, Sanz-Pérez A, Garrido-Cárdenas JA, et al.
The transition from MIRU-VNTR-based epidemiology studies in tuberculosis (TB) to genomic epidemiology has transformed how we track transmission. However, short-read sequencing is poor at analyzing repetitive regions such as the MIRU-VNTR loci. This causes a gap between the new ge…
Jiomekong A, Camara G
Epidemiological surveillance systems enable collection, analysis and dissemination of information on the monitored disease to different stakeholders. It may be done manually or using a software. Given the poor performances of manual systems, the software approach is generally ado…
Sadovska D, Ozere I, Pole I, Ķimsis J, Vaivode A, et al.
Background Tuberculosis remains a global health threat, and the World Health Organization reports a limited reduction in disease incidence rates, including both new and relapse cases. Therefore, studies targeting tuberculosis transmission chains and recurrent episodes are crucial…
Jajou R, Kohl TA, Walker T, Norman A, Cirillo DM, et al.
BackgroundWhole genome sequencing (WGS) is a reliable tool for studying tuberculosis (TB) transmission. WGS data are usually processed by custom-built analysis pipelines with little standardisation between them.AimTo compare the impact of variability of several WGS analysis pipel…
Eric Q. Mooring
…a range of considerations, including the underlying spatial epidemiology of the disease. This dissertation investigates the spatial epidemiology of yaws and tuberculosis. It also explores the implications of spatial epidemiology on the relative merits of a spatially targeted appr…
Chan, King-pui Florence, 陳璟珮
…e the possible effects of changes in human behaviour on the epidemiology of respiratory diseases and infections in Hong Kong during the COVID-19 pandemic. The first two chapters of the thesis focus on the effect of universal masking and social distancing on hospitalisations due t…
Carlos Cifuentes-González, Germán Mejía-Salgado, William Rojas-Carabali, Josué Tovar-Tirado, Luis Alejandro Diez-Bahamón, et al.
… its clinical importance, the global incidence and detailed epidemiology of scleritis are poorly understood due to its heterogeneity and rarity. This systematic review and meta-analysis aim to elucidate the worldwide incidence and epidemiological trends of scleritis, examining va…
Rina de Zwaan, Gerard de Vries, Ella Ubbelohde, Arnout Mulder, Miranda Kamst-van Agterveld, et al.
Whole genome sequencing (WGS) is able to identify epidemiological links between Mycobacterium tuberculosis isolates. Recent clustering can be ruled out using a pre-defined single nucleotide polymorphism (SNP) threshold. If WGS clusters grow significantly over time limited genetic…
Zheng MQ, Li XX, Xu R, Liu S, Rui ZY, et al.
… literature study. In this study, publications on molecular epidemiology were analyzed using bibliometric analysis. The statistical analysis of influential publications, journals, countries and authors was first conducted. Methods The Web of Science database was searched for publ…
Menean M, Scandale P, Apuzzo A, Barresi C, Checchin L, et al.
…-threatening inflammatory conditions. Understanding uveitis epidemiology, etiology, and clinical findings is fundamental for a prompt diagnosis and optimal patient management. The aim of the study is to report the epidemiology of uveitis in a national referral center in Northern …
Christian Gortázar
Article Figures and data Abstract eLife digest Introduction Results Discussion Materials and methods Appendix 1 Appendix 2 Data availability References Decision letter Author response Article and author information Metrics Abstract Quantifying pathogen transmission in multi-host …
Nicola Harvey, Guy McGrath, James O'Shaughnessy, Jamie A Tratalos, Brian Byrne, et al.
… health, biosecurity and the economy. The complexity of bTB epidemiology, driven by multiple host species, undetected transmission and incomplete diagnostic sensitivity, makes surveillance and control challenging. Pathogen whole-genome sequencing (WGS) can clarify transmission dy…
Joseph Crispell, Clare H. Benton, Daniel Balaz, Nicola De Maio, Assel Ahkmetova, et al.
Article Figures and data Abstract eLife digest Introduction Results Discussion Materials and methods Appendix 1 Appendix 2 Data availability References Decision letter Author response Article and author information Metrics Abstract Quantifying pathogen transmission in multi-host …
E. M. Belilovsky, Borisov Se
Ensuring effective epidemiological surveillance of tuberculosis is essential and one of the paramount tasks for any national tuberculosis control program. The article analyzes the organization of the tuberculosis epidemiological monitoring system at the level of the subject, base…
Jane E. Gross, Jason Fullmer, Gregory McCleland, Silvia M. Caceres, Katie R. Poch, et al.
BACKGROUND: Cystic Fibrosis (CF) Centers worldwide have reported healthcare-associated outbreaks of nontuberculous mycobacteria (NTM). We report a retrospective investigation of shared Mycobacterium abscessus strains among people with cystic fibrosis (pwCF) receiving care at Dell…
Natal’ya A. Bobotina, Ol’ga N. Men'shova
INTRODUCTION: Tuberculosis is an infectious disease that affects, among other things, the lungs, and is a serious public health problem worldwide. It is the leading cause of death among infectious diseases. AIM: Epidemiological analysis of morbidity with tuberculosis in the Russi…
Wei Zhang, Qing Wang, Liru Zhang, Jiangxiong Wu, Jinlu Liu, et al.
…, bacterial genotyping has made a great contribution to the epidemiology of drug-resistant bacteria, and it should gradually become the mainstream monitoring method to be implemented.