Showing 1–25 of 200 documents
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Akihiro Ohkado, Seiya Kato
Epidemiology of TB provides important information for clinical diagnosis. The risk of TB infection and disease development depends on exposure to bacilli, i.e., contact with infectious TB patients, host factors such as comorbidities, and socio-economic conditions. TB was called a…
Xiaoyu Lu, Yuan Jiang, Rui Zhang, Yangyi Zhang, Jing Li, et al.
**BACKGROUND:** Long-term transmission of multidrug-resistant tuberculosis (MDR-TB) challenges TB control by generating new cases and enabling the emergence of extensively resistant strains. We investigated its epidemiologic and bacterial drivers in Shanghai, China. **METHODS:**…
Asare P, Asante-Poku A, Osei-Wusu S, Otchere ID, Yeboah-Manu D
…, remains a global health problem. West Africa has a unique epidemiology of TB that is characterized by medium- to high-prevalence. Moreover, the geographical restriction of M. africanum to the sub-region makes West Africa have an extra burden to deal with a two-in-one pathogen. …
Azger Dusthackeer, Mahizhaveni Balasubramanian, Sam Ebenezer Rajadas, Christy Rosaline Nirmal, Padmasini Elango, et al.
**INTRODUCTION:** The rise of drug-resistant tuberculosis poses a significant challenge in patient management. Epidemiological cut-off values define drug resistance in. In our previous study, we reported deviations from the WHO-recommended epidemiological cut-off values and ident…
Dixit A, Ektefaie Y, Kagal A, Freschi L, Karyakarte R, et al.
…orld's burden, are not well studied. We conducted a genomic epidemiology study to compare epidemiological success, host factors, and drug resistance among the 4 major Mycobacterium tuberculosis (Mtb) lineages (L1-L4) circulating in Pune, India. Methods We performed whole-genome s…
Han Z, Li J, Sun G, Gu K, Zhang Y, et al.
Background Multidrug-resistant tuberculosis (MDR-TB) has become a major public health problem in China, with mounting evidence suggesting that recent transmission accounts for the majority of MDR-TB. Here we aimed to reveal the transmission pattern of an MDR-TB outbreak in the Ji…
А. А. Yakovlev, M. S. Kornilov, С. Н. Жданова, N. A. Polyakova, M. А. Yakovlev
Objective. To identify the spectrum of Mycobacterium tuberculosis genotypes circulating in Primorsky Krai and their significance in shaping the epidemiological situation. Materials and methods . The prevalence of multidrug-resistant tuberculosis (MDR-TB) was assessed based on mon…
Irina Kostyukova, О. А. Пасечник, Igor Mokrousov
Background. Tuberculosis (TB) infection remains relevant as one of the leading public health problems in Russia. The aim. To characterize the dynamics and trends of epidemiological manifestations of TB infection in the Omsk region. Materials and methods . An observational descrip…
Bhembe NL, Green E
…al challenge. Making it imperative to examine the molecular epidemiology of drug resistant tuberculosis. Molecular epidemiology methods can evaluate transmission patterns and risk factors, ascertain transmission cases of multidrug-resistant tuberculosis (MDR-TB) and furthermore d…
Starshinova A, Belyaeva E, Doktorova N, Korotkevich I, Kudlay D
Aim Because of the COVID-19 pandemic, many support programs for tuberculosis (TB) patients have been discontinued and TB mass screening activities decreased worldwide, resulting in a decrease in new case detection and an increase in TB deaths (WHO, WHO global lists of high burden…
A. G. Aleshina, М. А. Patyashina
In the Republic of Tatarstan, in the period 2012 to 2021 we observed a twofold decrease in the incidence of tuberculosis: from 48 cases per 100 thousand population to 23.4 cases per 100 thousand population. However, there is an increase in the proportion of patients with respirat…
Dolynska MG, Dolynskyi GA, Duhlii TV, Petrenko VI
Objective The aim: To analyze molecular epidemiology features of M. tuberculosis in Kyiv oblast; and to identify the safest mode of TB treatment, which will allow clinicians to minimize the risk of drug-resistant strains nosocomial transmission. Patients and methods Materials and…
Bainomugisa A, Meumann EM, Rajahram GS, Ong RT, Coin L, et al.
…alth priority in eastern Malaysia. Knowledge of the genomic epidemiology of tuberculosis can help tailor public health interventions. Our aims were to determine tuberculosis genomic epidemiology and characterize resistance mutations in the ethnically diverse city of Kota Kinabalu…
Kalpesh Khutade, Harshada Shah, Dimple Yadav
…rculosis and multidrug resistant tuberculosis in the world. Epidemiology is the study of disease in population. Epidemiology is the study of the frequency, pattern, and distribution of determinants (causes, risks) of health states and conditions (not just disease) in the general …
Yi Liu, Jue Wang, Xiaojie Wan, Wang Peng, Jingwei Guo, et al.
**BACKGROUND:** Drug-resistant tuberculosis (DR-TB) remains a major public health challenge in China, yet long-term epidemiological data from key regions such as Hunan Province in South-Central China are still limited. **OBJECTIVE:** This study aimed to characterize the epidemio…
Jiang H, Zhang G, Yin J, Zhao D, Liu F, et al.
Background In 2005, China established an internet-based Tuberculosis Information Management System (TBIMS) to monitor changes in tuberculosis (TB). Many scholars have conducted epidemiological research using TBIMS; however, few studies assessing control strategies have been perfo…
Yu Y, Xiang Y, Liu H, Yang S, Li M, et al.
Objectives This study aimed to investigate the epidemiological and drug resistance (DR) characteristics of extrapulmonary tuberculosis (EPTB) in South-Central China. Methods EPTB inpatients who were culture-positive for Mycobacterium tuberculosis were retrospectively included in …
Oliveira O, Gaio R, Carvalho C, Correia-Neves M, Duarte R, et al.
Background Increasing multidrug-resistant tuberculosis (MDR-TB) incidence is a major threat against TB eradication worldwide. We aim to conduct a detailed MDR-TB study in Portugal, an European country with endemic TB, combining genetic analysis and epidemiological data, in order …
Almeida SM, Malaspina AC, Leite CQF, Saad MHF
A drug resistance survey involving Mycobacterium tuberculosis isolated from patients of a tertiary Hospital in the Rio de Janeiro city (RJ), Brazil, between the years 1996 and 1998 revealed a high frequency of isoniazid (HR) resistance. These isolates were revisited and genotyped…
Getachew Seid, Andrea Maurizio Cabibbe, Betselot Zerihun, Ayinalem Alemu, Getu Diriba, et al.
**BACKGROUND:** The genotyping of the M. tuberculosis complex has significantly enhanced the comprehension of transmission dynamics and is employed to substantiate transmission dynamics among epidemiologically interconnected cases. This investigation sought to examine genomic div…
Gülnur Tarhan, Salih Cesur, İsmail Ceyhan, Rıza Durmaz
Aim of the study This study was planned to determine the second generation drug resistance and molecular epidemiological profile of multidrug resistant Mycobacterium tuberculosis strains isolated from different geographical regions of Turkey. Methods In our study, 63 MDR M. tuber…
Rıza Durmaz, Salih Cesur, İSMAİL CEYHAN, Günnur Tarhan
<span style="color: rgb(33, 37, 41); font-family: "Noto Sans Display Light", serif; font-size: 17.6px; text-align: justify; background-color: rgba(245, 245, 245, 0.38);">Introduction: This study was planned to determine the second line drug resistance and molecular epid…
Gülnur Tarhan, İsmail Ceyhan, Rıza Durmaz, Salih Cesur
Introduction: This study was planned to determine the second line drug resistance and molecular epidemiological profiles of multidrug resistant Mycobacterium tuberculosis isolates isolated from different geographical regions of Turkey.
 Material and Method: In our study, 63 …
Gülnur Tarhan, İsmail Ceyhan, Rıza Durmaz, Salih Cesur
Introduction: This study was planned to determine the second line drug resistance and molecular epidemiological profiles of multidrug resistant Mycobacterium tuberculosis isolates isolated from different geographical regions of Turkey.Material and Method: In our study, 63 MDR M. …
Nada K. Alharbi, Arwa R. Elmanakhly, Majid Alhomrani, Abdulhakeem S. Alamri, Rasha Mosbah, et al.
There is growing concern regarding biofilm-producing methicillin-resistant Staphylococcus aureus (MRSA) due to the sudden rise in infection rates and associated morbidity and mortality. Therefore, epidemiological studies, including molecular typing and correlation analysis, are e…