Showing 1–16 of 16 documents
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Misra UK, Kalita J, Kumar M
…articipants This is a single-center, open-label, randomized clinical trial conducted from October 2015 to April 2017 in India. Patients were randomized in a 1:1 ratio to arms receiving saline only or saline plus fludrocortisone, in addition to a standard treatment of 4 antituberc…
Mritunjai Kumar, Anu Singh, Rajni Singh, Nikita Dhar, Jagbir Singh, et al.
…s with tuberculous meningitis (TBM) remains uncertain. This trial compared the effectiveness and safety of ethambutol (ETM) versus streptomycin (STM) during the intensive phase. **METHODS:** This is an investigator-initiated, single-center, open-label, randomized controlled tria…
Manal Arshad Malik, Aleena Kamran, Dua Ahsan, Aafia Amjad, Sara Moatter, et al.
…d across major databases, including PubMed, Google Scholar, ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform, and the ISRCTN Registry. The search strategy used terms like ("tubercular meningitis" OR "TBM" OR "TB meningitis") AND ("diagnosis" OR "treatme…
Inbaraj LR, Manesh A, Ponnuraja C, Bhaskar A, Srinivasalu VA, et al.
… in the field of TBM over the last two decades and only few trials have evaluated a composite of these strategies in the overall outcomes of TBM. Methods An open label, parallel arms, randomized controlled superiority trial will be conducted among 372 participants across 6 sites …
Bjerrum S, Schiller I, Dendukuri N, Kohli M, Nathavitharana RR, et al.
…d symptoms).The proposed role for LF-LAM is as an add on to clinical judgement and with other tests to assist in diagnosing tuberculosis. Search methods We searched the Cochrane Infectious Diseases Group Specialized Register; MEDLINE, Embase, Science Citation Index, Web of Scienc…
Mikashmi Kohli, Leeberk Raja Inbaraj, Angela Salomon, Katie Scandrett, Alexei Korobitsyn, et al.
…:** We searched the Cochrane Central Register of Controlled Trials, MEDLINE, Embase, Science Citation Index, Latin American Caribbean Health Sciences Literature, Scopus, ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform, the International Standard Random…
Kohli M, Schiller I, Dendukuri N, Dheda K, Denkinger CM, et al.
…ican Caribbean Health Sciences Literature (LILACS), Scopus, ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform, the International Standard Randomized Controlled Trial Number (ISRCTN) Registry, and ProQuest up to 7 August 2017 without language restriction.…
Misra UK, Kumar M, Kalita J
…le-centre, open-label, parallel group randomized controlled trial was conducted from May 2017 to June 2019 in India. Treatment-naïve patients with TBM fulfilling the inclusion criteria were randomized to four drug ATT regimens (rifampicin, isoniazid, ethambutol and pyrazinamide) …
Xing XW, Zhang JT, Ma YB, He MW, Yao GE, et al.
…d in conjunction with conventional microbiological testing. Trial Registration: Chinese Clinical Trial Registry, ChiCTR1800020442.
Van Hoving DJ, Griesel R, Meintjes G, Takwoingi Y, Maartens G, et al.
…ential sources of heterogeneity in test accuracy, including clinical setting, ultrasound training level, and type of reference standard. Search methods We searched for publications in any language up to 4 April 2019 in the following databases: MEDLINE, Embase, BIOSIS, Science Cit…
Di Tanna GL, Khaki AR, Theron G, McCarthy K, Cox H, et al.
…ted with Xpert MTB/RIF. Methods We searched PubMed, Embase, ClinicalTrials.gov, and the Pan African Clinical Trials Registry from inception to Feb 1, 2018, for randomised controlled trials (RCTs) comparing the use of Xpert MTB/RIF with sputum smear microscopy as tests for tubercu…
Leeberk Raja Inbaraj, Vignes Anand Srinivasalu, Mukesh Kumar Sathya Narayanan, Adhin Bhaskar, Jefferson Daniel, et al.
…is, we searched the Cochrane Central Register of Controlled Trials, MEDLINE, Embase, the Science Citation Index and BIOSIS previews, WHO Global Index Medicus, and Scopus databases, for articles published from Jan 1, 1946, to Oct 2, 2023, using specific search terms such as "Tuber…
Ndege R, Ngome O, Vanobberghen F, Bani F, Temba Y, et al.
…ts with suspected extrapulmonary tuberculosis. Methods This trial in adults with suspected extrapulmonary tuberculosis was performed in a rural and an urban hospital in Tanzania. Participants were randomized 1:1 to intervention or routine care, stratified by site and HIV status. …
Loan JJM, Poon MTC, Tominey S, Mankahla N, Meintjes G, et al.
…ify prognostic indicators, we aimed to compare survival and clinical outcome following VPS placement between all studied causes of hydrocephalus in HIV infected patients. Methods The following electronic databases were searched: The Cochrane Central Register of Controlled Trials,…
David B Meya, Fiona V Cresswell, Biyue Dai, Nicole Engen, Kogieleum Naidoo, et al.
…We performed a double-blind, randomized, placebo-controlled clinical trial involving adults with tuberculous meningitis in Indonesia, South Africa, and Uganda. We assigned persons with and those without human immunodeficiency virus (HIV) coinfection to receive standard daily ison…
Rakshit Kumar Singh, Chehak Bewtra, Praveena Kher
…ven the most effective treatment can cause vision loss, and clinical recovery is not always permanent. Ocular tuberculosis frequently results in permanent impairment, lowering patients' quality of life.
 Objective: This article reports the various known presentations of ocul…