Showing 176–200 of 200 documents
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Bhaskar Shenoy, Harshini T Reddy
C-Tb is a novel diagnostic test for latent tuberculosis (TB) infection. It is a skin test based on the principle of tuberculin skin test containing early secreted antigenic target 6 (ESAT-6) and culture filtrate protein 10 (CFP-10). It is important to understand newer diagnostics…
Rasmus Laub, Christian Niels Meyer
<b>Background:</b> Denmark has a low and declining tuberculosis (TB) incidence rate of 5.0/10<sup>5</sup>. Close contacts of newly diagnosed contagious TB patient are offered contact tracing with chest X-ray, interferon gamma release assay, clinical examination, and if relevant s…
Shereen Katrak, Janice Westenhouse, Pennan M. Barry, Jennifer Flood
Abstract Background Tuberculosis (TB) disease in persons who have received organ transplantation causes high morbidity, but the epidemiology and clinical features of this problem remain poorly described. Methods Using California TB registry data from 2010–2017, we describe clinic…
Cecilia F Peña-Puga, Oscar Morado‐Aramburo, Darwin Lambraño-Castillo, Jennifer Cuellar‐Rodríguez
Abstract Background Tuberculosis is an important opportunistic infection that affects transplant recipients; the risk of active infection increases significantly when compared with the general population. Most disease results from reactivation of latent infection, being extrapulm…
Diogo Canhoto, Barbara Nascimento, António Jorge Ferreira, Paulo Cravo Roxo
… hypothesised to lead to difficult-to-predict variations in tuberculosis (TB) incidence, as domestic contacts are prolonged and occupational and social exposures become rarer and shorter. <bold>Objective:</bold> To compare latent tuberculosis (LT) incidence before and following t…
Felix Ehret, Fatma Ben Abid, Victor Teatini Ribeiro, Roddy Bodden, Feres Camargo Maluf, et al.
Introduction Tuberculosis (TB) is a global infectious disease that has plagued human beings for centuries. It currently ranks as one of the primary causes of death by a single agent. Treatment of latent TB (LTBI) is one of the cornerstones used to prevent the activation of TB. Th…
Jung JH, Choi S, Kang Y, Cho DC, Lee SM, et al.
Introduction Tuberculosis (TB) spondylitis, also known as Pott's disease, is a severe form of extrapulmonary TB. Infliximab treatment for Crohn's disease (CD) patients increases the risk of TB, and is likely to increase the risk of TB spondylitis as well. Case presentation We rep…
Kim D, Lee S, Kang SH, Park MS, Yoo SY, et al.
Purpose Tuberculosis (TB) is one of the most important diseases that cause significant mortality and morbidity in young children. Data on TB transmission from an infected child are limited. Herein, we report a case of disseminated TB in a child and conducted a contact investigati…
David L Fuller, Paul Holden
…und Silicosis is a known risk factor for the development of tuberculosis (TB) disease, occurring commonly among miners. “Silico-tuberculosis” (silico-TB) describes individuals affected by both silicosis and TB. Here we characterize an outbreak of silico-TB among stone countertop …
Y. Nakano, Kenta Yamada, Koji Suzuki, Motoko Yasutomi, Motohiro Takeuchi, et al.
Pancreatic tuberculosis (TB) is a rare form of extrapulmonary TB.1 We present a case of pancreatic TB requiring differentiation from pancreatic neoplasms. A 13-year-old boy born in the Philippines presented with fever and back pain lasting 6 days. While living in the Philippines,…
Nyein Thu, Diane O’meara, Gerrit Woltmann, Aye Aye Thi
…treatment has been associated with 5-fold increased risk of tuberculosis (TB). Latent TB infection (LTBI) screening should be performed on all inflammatory bowel disease (IBD) patients prior to initiating biologic treatment. We analysed cases of active TB after receiving biologic…
Jody Boffa, Dina A. Fisher, Maria Mayan, Reginald S. Sauve, Tyler Williamson
To the Editors: INTRODUCTION Although curable, tuberculosis (TB) is the leading cause of AIDS-related morbidity and mortality globally.1 South Africa has the world's highest burden of HIV (7 million people)2 and reports 23% of the global TB-HIV burden.3Mycobacterium tuberculosis …
Son M, Park YS, Jung MH, Kang JH, Choi UY
Objectives In South Korea, latent tuberculosis infection (LTBI) screening is a critical strategy associated with efforts to reduce the incidence of tuberculosis (TB). Currently, only children with a known history of TB contact are considered as pediatric high-risk groups for LTBI…
Clare Bristow, Uli Schwab
…nodeficiency Virus (HIV) are at an increased risk of latent Tuberculosis (TB) reactivation. HIV TB concurrent infection increases mortality and reduces patient quality of life. Screening for latent TB allows treatment to commence, preventing reactivation. In accordance with Briti…
Meher Sasmita, Meher Bhanjan, Rathore Rajkumari, P. G Dhone, Rai Neeta
HIV is the most important cause of death amoung tuberculosis patient. About 25 % of all causes of death. HIV promote progression of latent TB infection, which become difficult to diagnose initially later on comorbidity and mortality leads to late diagnosis and death of patients. …
David Landsman, Ahmed Abdelbasit, Christine Wang, Michael Guerzhoy, Ujash Joshi, et al.
Abstract Background Tuberculosis (TB) is a major cause of death worldwide. TB research draws heavily on clinical cohorts which can be generated using electronic health records (EHR), but granular information extracted from unstructured EHR data is limited. The St. Michael’s Hospi…
Samantha Cheryl Kumar, George Ipe Vettiyal, Winsley Rose, Joy Michael, J Visalakshi, et al.
**OBJECTIVES:** The mainstay of treatment for pediatric rheumatological disease is disease-modifying anti-rheumatic agents which are immunosuppressive in nature and increase the susceptibility to tuberculosis. The aims and objectives were to evaluate the performance of the Quanti…
Jee Whang Kim, Rahul Patel, Gerrit Woltmann, Raman Verma, Pranabashis Haldar
…t impact on healthcare delivery for other disease including tuberculosis (TB). Leicester has faced a particularly prolonged period of disruption after imposition of local lockdown measures within 7 weeks of the national lockdown. <h3>Objectives</h3> To evaluate the impact of the …
Rim Masri, Mayssoun Koubaissi, Zeinab El Mawla, Abdallah Abd AlSater, Mohammad Yassin, et al.
The coexistence of tuberculosis (TB) and diabetes mellitus (DM) represents a threatening health challenge, creating a dangerous double burden, particularly in low- and middle-income countries. DM not only increases susceptibility to TB but also worsens clinical outcomes. To asses…
Modi AR, Miranda CC, Procop GW, Foster CB, Harrington S, et al.
Tuberculosis (TB) in the health care worker demands orchestrated efforts from health care institutions to promptly identify cases and address community risk. We describe a pediatric intensive care unit nurse with latent TB infection who developed hemoptysis and a lung infiltrate …
Surve S, Naukariya K, Shah I
…ticle is to review various studies conducted in relation to diagnosis, treatment and management of Latent TB Infection (LTBI) in under-five children, thus highlighting research gaps and further scope of improvements with respect to Indian context. The methodology involved literat…
Wang Z, Posey DL, Brostrom RJ, Morris SB, Marano N, et al.
…gee children aged 2-14 years who were diagnosed with latent tuberculosis infection (LTBI) during a required overseas medical examination. Study design We compared overseas and US interferon-γ release assay (IGRA)/tuberculin skin test (TST) results and LTBI diagnosis; assessed pos…
Della Bella C, Motisi MA, Venturini E, D'Elios S, Asvestopoulou E, et al.
… High-accuracy diagnostic screening tests for Mycobacterium tuberculosis (MTB) infection are required, primarily to detect patients with latent infections (LTBIs) in order to avoid their progression to active tuberculosis disease. The performance of the novel IGRA LIOFeron®TB/LTB…
Camila Lima, Karoline Soares Garcia, Bianca Pocopetz Facas, Matheus Freitas Cardoso de Azevedo, Natália Sousa Freitas Queiroz, et al.
BACKGROUND: Despite the decline in the incidence of Tuberculosis (TB) worldwide, this disease still causes high rates of morbimortality. It is estimated that TB caused 1.3 million deaths worldwide in 2017. Brazil is an endemic country and it counts nearly 70,000 new cases of TB p…
Yahya Almodallal, Daniel Whitehurst, Sing Sing Way, Jane Koo, Ashish Kumar
…he Editor: We describe the first reported case of pulmonary tuberculosis (TB) complicated by fulminant drug reaction with eosinophilia and systemic symptoms (DRESS) in the context of markedly elevated C-X-C motif chemokine ligand 9 (CXCL9) levels. Management required multidiscipl…