Showing 176–200 of 200 documents
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Neha Gupta, Bineeta Kashyap, Pooja Dewan, Puneeta Hyanki
…s. We aimed to study the serum levels of IL-12 and IFN-γ in pediatric tuberculosis and their correlation with clinical and microbiological features. Material and Methods: A case-control study was conducted on 60 microbiologically confirmed (smear and/or culture and/or cartridge-b…
Mejia- Mertel J, Rojas -Hernandez J
…nical manifestations in HTLV-1, still studies are needed in pediatric population to improve diagnosis and treatment of infected patients. Methods Descriptive, retrospective cohort study, conducted in our referral pediatric hospital in Cali, Colombia. Included pediatric patients (…
Jayagandan S, Singh J, Mudliar SR, Shankar P, Maurya AK, et al.
…ective Microbiological confirmation of tuberculosis (TB) in pediatric cases is challenging due to its paucibacillary nature and difficulty in specimen collection. This study aimed to validate stool as an alternative sample for the diagnosis of pediatric pulmonary TB via Xpert MTB…
Aole Li, Yuhang Wu, Xinxin Zeng, Xi Zhang, Jiong Li, et al.
**OBJECTIVE:** Pediatric tuberculosis (TB) remains an important part of the global TB burden; however progress in this population has been slower and less consistent than that in adults. The influence of recent epidemiological shifts, including those following the COVID-19 pandem…
Jakhar S, Bitzer AA, Stromberg LR, Mukundan H
…l ages. However, the disease presents a larger challenge in pediatric populations, partially owing to the lack of reliable diagnostic standards for the early identification of infection. Currently, there are no biomarkers that have been clinically validated for use in pediatric T…
Gaensbauer J, Broadhurst R
…ests and broader application in non-sputum samples for both pediatric pulmonary and extrapulmonary tuberculosis. Finally, recent studies have provided solid evidence in support of shorter treatment courses for pediatric latent tuberculosis infection, such as 12 weeks of weekly is…
Kumar NP, Hissar S, Thiruvengadam K, Banurekha VV, Suresh N, et al.
Pediatric TB poses challenge in diagnosis due to the paucibacillary nature of the disease. We conducted a prospective diagnostic study to identify immune biomarkers of pediatric TB and controls (discovery cohort) and obtained a separate "validation" cohort of confirmed cases of p…
Chu P, Chang Y, Zhang X, Han S, Jin Y, et al.
ABSTRACT Pediatric tuberculosis (TB) is a serious infectious disease that affects many children worldwide and is more likely to be extrapulmonary than adult TB. However, the clinical and epidemiological profile, and cost burden of pediatric extrapulmonary TB (EPTB) in China remai…
DesJardin CP, Chirenda J, Ye W, Mujuru HA, Yang Z
Background Historical neglect of pediatric tuberculosis (TB), compounding the absence of a universally effective vaccine, highlights the importance of successful treatment in combating the global epidemic. Furthermore, compliance with international standards of pediatric TB treat…
Gebremichael B, Abebaw TA, Moges T, Abaerei AA, Worede N
…limited. Therefore this study aimed to assess predictors of pediatric Tuberculosis in Public Health Facilities. Methods Unmatched case control study among a total samples of 432 (144 cases and 288 controls) were done from August to December 2016 in Bale zone, South East Ethiopia.…
Gehang Ju, Xin Liu, Yeheng Peng, Wenyu Yang, Nuo Xu, et al.
… optimize the sampling strategy for isoniazid in East Asian pediatric populations. We employed a model-informed optimization approach based on INH population pharmacokinetic (PopPK) models. Methods: We selected PopPK models for children and East Asian adults and optimized the sam…
Saleem Ahmed, Qazi Mumtaz Ahmad, Tazeem Akhtar, Muhammad Usman, Sobia Al Rehman, et al.
…amycin prevalence which create resistant in newly diagnosed pediatric patients having pulmonary infections. Objectives: This scientific research was conducted to evaluate the prevalence of antibiotics resistivity in pediatric children specifically under age. The primary antibioti…
Letícia Baltar Sobreira, Paula de Souza Silva Freitas, Luciana de Cássia Nunes Nascimento, Anne Caroline Barbosa Cerqueira Vieira, Carolina Maia Martins Sales, et al.
…cessively resistant and multidrug resistant tuberculosis in pediatric patients. Methods: this is a scope review of the literature, with a guiding question: “What is the scientific evidence on multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis in…
М. С. Опанасенко, O.V. Tereshkovich, S. М. Shalahai, L. І. Levanda, T.V. Kirillova
Pediatric surgeons often to have different indications for the diagnosis and treatment of pathology of the thoracic cavity. Often, only invasive techniques, such as a biopsy, can help diagnose and determine further treatment. One of the reasons for performing thoracic operations …
Olivia F. Hunter, Furaha Kyesi, Amrit Ahluwalia, Zeinabou Niamé Daffé, Patricia Munseri, et al.
…in whom diagnostic confirmation is challenging. We assessed pediatric IPT implementation and adherence at a pediatric HIV clinic in Tanzania. Methods: Eligible HIV-infected children aged 1-15 years receiving care at the DarDar Pediatric Program in Dar es Salaam who screened negat…
Eugenia Legan, J.L. Bessich, Alexander M. El‐Ali, Eleanor D. Muise
… the use of bronchial airway stents has been limited within pediatrics. In adults, airway stents serve to maintain airway patency in both intrinsic and extrinsic disease, with most stents placed for malignant disease. In adults with tracheobronchomalacia, a trial of silicone sten…
Kamble B, Malhotra S
…a, all ages have assumed importance including the burden of pediatric TB. The current study was carried out to study the profile of pediatric TB patients and factors associated with treatment outcome of these patients registered in Faridabad district of Haryana, India. Methods Th…
Herdea A, Marie H, Negrila IA, Abdel Hamid Ahmed AD, Ulici A
Background Pediatric osteoarticular tuberculosis (TB) remains a significant global health challenge, particularly in resource-limited settings, where delayed diagnosis and treatment frequently lead to severe long-term complications. Despite advancements in TB control, skeletal TB…
A J Cabrera Goncalves, B C Adkinson, D Ashkin
Abstract Introduction Interventional bronchoscopy in pediatrics is challenging due to small airway caliber, limited pulmonary reserve, and scarce appropriately sized instrumentation. Expertise is often concentrated in high-volume centers, making complex airway interventions diffi…
Dong-Hyun Lee, Young‐Jin Choi, Jieun Kim, Eunhee Han, Mi Hyun Bae
…bution of bacterial species in NPS specimens collected from pediatric and adult patients by employing RT-PCR (Allplex respiratory panel 4, RP4, Seegene) to estimate its applicability in a panel-based assay for detecting respiratory viruses. Methods: We used 271 and 173 NPS specim…
Jeffrey Hafkin, MD
The purpose of this trial is to determine the pediatric dose of delamanid that is equivalent to the adult dose already shown to be effective against multidrug-resistant tuberculosis. This trial will investigate the pharmacokinetics (PK) and safety of delamanid administered for 1…
Ahmed R. Rezk, Somaia Abdelhammed Bawady, Nashwa Naguib Omar
…orldwide threat in intensive care units particularly in the pediatric intensive care units with a major cause of morbidity and mortality among this age group. The aim of the study is to determine the prevalence and risk factors predisposing to multidrug-resistant organisms (MDROs…
Awewura Kwara, MD
Lack of quality-assured pediatric formulations of the first-line antituberculosis (anti-TB) drugs is barrier to optimized tuberculosis (TB) treatment outcome in children. In 2010 and subsequently modified in 2014, the World Health Organization (WHO) recommended increased dosages …
Luciana Cotignola, Aixa Reusmann, Martín Rubio, Enrique Paz, Víctor Ayarzabal, et al.
…ulosis (ATB) is a rare presentation of tuberculosis (TB) in pediatric patients, and its diagnosis can be challenging. This study aimed to analyze the role of surgery in patients with ATB presenting with acute abdomen. We conducted a retrospective analysis of pediatric patients un…
Piastra M, Picconi E, Morena TC, Valentini P, Buonsenso D, et al.
…TB) in the adult setting, and it is even less common in the pediatric population. The presence of comorbidities and the possibility of a delayed diagnosis may further impair the clinical prognosis of critically ill patients with disseminated TB and acute respiratory failure. In t…