Showing 176–200 of 200 documents
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Pérez-López LM, Subirá-Álvarez T, Martínez-Ruíz A, Noguera-Julian A, Moreno-Romo D, et al.
…proximately 10% of the total extrapulmonary tuberculosis in pediatric patients. Its low prevalence and nonspecific clinical presentation lead to a late diagnosis and elevated risk of sequelae. Patients and methods This retrospective study included seven pediatric patients with no…
Shah JA, Warr AJ, Graustein AD, Saha A, Dunstan SJ, et al.
…hages, BCG-specific T cell responses, and susceptibility to pediatric and adult TB in human populations. BHLHE40 single-nucleotide polymorphism (SNP) rs4496464 was associated with increased BHLHE40 expression in monocyte-derived macrophages and increased IL-10 from peripheral blo…
Dhruv Gandhi, Meenakshi Dey, Sonal Patil, Dhruv Mamtora, Ira Shah
Abstract Background The diagnosis of pediatric tuberculosis (TB) remains challenging due to difficulties in specimen collection and the paucibacillary nature of the disease. While Mycobacteria Growth Indicator Tube (MGIT) culture is the gold standard, its long turnaround time lim…
Stuti Sharma, Anurag Agarwal, Ashwani Khanna
…is one of the deadliest forms of tuberculosis especially in pediatric population. **AIM:** To study the clinico-epidemiological profile of 75 cases of pediatric TB meningitis and its co-relation with CBNAAT/TRUENAT positivity. **STUDY DESIGN:** Prospective study in children and…
Kim JH, Lee JS, Choi BY, Cheon YH, Yoo SJ, et al.
…n the systematic review, we identified 58 ITBM, including 9 pediatric, cases in the literature published from 1981 to 2021 25 (43.1%) immunocompromised and 33 (56.9%) non-immunocompromised patients. Immunocompromised cases had a significant shorter symptom duration (median 30.0 v…
Javeed A. Shah, Alex J. Warr, Andrew D. Graustein, Aparajita Saha, Sarah J. Dunstan, et al.
…(MDM), BCG-specific T cell responses, and susceptibility to pediatric and adult TB. Results SNP BHLHE40 rs4496464 was associated with increased BHLHE40 expression in MDMs and increased IL-10 from both peripheral blood dendritic cells and MDMs after LPS and TB whole cell lysate st…
Newtonraj A, Venables E, Selvaraj K, Kundu D, Purty AJ, et al.
… in 2016 as the initial diagnostic test for extrapulmonary, pediatric, and human immunodeficiency virus-associated tuberculosis (TB) and as an add-on test for sputum microscopy-negative patients under Revised National TB Control Programme, Puducherry, India. We intended to study …
Khadija Kamal, Aneela Shaheen
…ed to compare the biochemical and hematological profiles of pediatric patients diagnosed with PTB and EPTB at Gulab Devi Teaching Hospital. Methodology: This descriptive case series included 120 pediatric patients under 14 years of age diagnosed with TB over a three-month period.…
Ewelina Truszkowska, Sandra Rutkowska, Katarzyna Derwich, Katarzyna Smalisz, Jolanta Goździk, et al.
…, clinical characteristics, treatment, and outcome of TB in pediatric patients with malignancy and hematopoietic stem cell transplant (HSCT) recipients in Poland. **METHODS:** Five cases of TB were reported from all Polish pediatric hematology, oncology, and transplant centers a…
Ritu Singhal, Resmi Ravindran, Sanket Poniya, Lokender Kumar, Vithal P Myneedu, et al.
…ding clinically diagnosed cases), extrapulmonary TB (EPTB), pediatric TB (PEDTB), and TB in HIV-positive individuals. Control groups included healthy individuals and lung disease patients, where TB was ruled out by liquid culture (disease controls). The results demonstrated the u…
Sharawat IK, Ramachandran A, Panda PK, Kumar V, Sherwani P, et al.
…s (12 died, 13%). In multivariate analysis, a high baseline Pediatric Cerebral Performance Category (PCPC) score, brain infarction in neuroimaging, tonic motor posturing, younger age, and stage III TBM were independent predictors of poor functional outcomes. The final model showe…
Kim J, Spears I, Erice C, Kim HH, Porter NA, et al.
…egin to understand the alterations to the brain lipidome in pediatric TB meningitis, we utilized our previously published young rabbit model of TB meningitis and applied mass spectrometry (MS) techniques to elucidate spatial differences. We used matrix assisted laser desorption/i…
Pradhan NN, Paradkar MS, Kagal A, Valvi C, Kinikar A, et al.
…and Xpert ® MTB/RIF Ultra (Ultra) performance in diagnosing pediatric tuberculous meningitis (TBM). METHODS: We conducted a study among children with suspected meningoencephalitis in Pune, India. Clinical, radiological, laboratory, and treatment data were analyzed to classify dis…
Mohd Jaish Siddiqui, Yang Liu, Yu Zhu, Qin Guo, Chaomin Wan, et al.
…udies, particularly among the older age groups,5 but in the pediatric series, we found a female predominance accounting for 56% while the male 40%, 1 patient was not included due to missing gender. A total of 36% (9/22) cases were diagnosed with PTB, 12% (3/22) with miliary TB an…
A J, Ratageri VH, Illalu S, Fattepur SR, Wari PK
…spective observational study was conducted at Department of Pediatrics, Karnataka Institute of Medical Sciences (KIMS), Hubli from December 2015 through November 2016. All children with clinically suspected tuberculous meningitis (TBM) were included in the study. These children u…
Kardelen Türközü Kanter, Nihal Olgaç Dündar, Fatma Kuşgöz, Ayşegül Elvan Tüz, Eda Karadağ Öncel, et al.
… Here, we presented a 12-year-old girl who presented to our pediatric emergency department with paraparesis.
Zarra F, Shahid AH, Gandhi DN, Salazar LRM, Chaurasia B
…ost classic and widely used treatments for hydrocephalus in pediatric patients. Migration and externalization of the distal end of the catheter through the rectum are extremely rare complications of intestinal perforation with devastating consequences such as meningitis or perito…
Shamaeel, Farzana Shiakh, Ghulam Shabbir Laghari, Yasmeen Memon
…: Cross sectional descriptive study. Setting: Department of Pediatrics, Liaquat University Hospital, Jamshoro / Hyderabad. Period: Six months from 20-08-2016 to 20-02-2017. Material and Methods: A total of 189 children with history of fever (axillary temperature >37.2°C) for ≥…
Y. Bouktib, Abidine Abidine, D. Basraoui, H. Jalals
…neuromeningeal tuberculosis, collected in the Department of Pediatrics A and Radiology of the Mother and Child Hospital of the Mohammed VI University Hospital Center of Marrakech over a period of 7 years (2012-2017). Brain CT was performed in all patients and brain MRI in 5 patie…
VaishaliR Ghane, Preeti Shanbag, Ashish Meshram
Pediatric neurotuberculosis manifests commonly as tuberculous meningitis and intracranial tuberculomas. The ratio of occurrence of intracranial to intraspinal tuberculoma reported is 42:1. Intramedullary tuberculomas (IMTs) are rare, and the coexistence of intramedullary and intr…
Soriano-Arandes A, Brugueras S, Rodríguez Chitiva A, Noguera-Julian A, Orcau À, et al.
…children under 2 years old. Extrapulmonary TB forms in this pediatric age remain a challenge and require prompt diagnosis and treatment in order to prevent them. The presence of tachypnea at the time of TB diagnosis is an independent associated factor to the development of TB com…
Gui-Xiang Jian, Yanfeng Huang
…ren with tuberculosis, which can rapidly assist to diagnose pediatric tuberculosis.
Chinchu Rajan, Santanu Deb, Palash Ranjan Gogoi, Prasenjit Paul, Sabrina Yesmin, et al.
…). Design: Prospective observational Setting: Department of Pediatrics & Neonatology, Nazareth Hospital, Shillong, Meghalaya. Participants:All children below 18 completed years of age diagnosed with any form of tuberculosis. Main outcome measures: Various demographic details,…
Isaac H Y Chan, Scott C. Roberts, Patrick G T Cudahy
…ith positive PCR. 115 (67%) were male. 7 cases (4%) were in pediatric patients. 140 (82%) patients were foreign born. There were 137 cases (80%) of pulmonary TB, 61 cases (36%) of extrapulmonary TB, and 27 (16%) cases with both pulmonary and extrapulmonary TB. The most common chi…
van Toorn R, Solomons R
…S IN CHILDREN: Ronald van Toorn, Regan Solomons Seminars in Pediatric Neurology Volume 21, Issue 1, March 2014, Pages 12-18 Tuberculous meningitis (TBM), the most devastating manifestation of tuberculosis, is often missed or overlooked because of nonspecific symptoms and difficul…