Showing 176–200 of 200 documents
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Siqueira Santos LF, Vilarino Carneiro PH, Alves de Oliveira Serra MA, Hunaldo Dos Santos L, Pinto de Andrade HL, et al.
Introduction The objective was to analyze the prevalence trend, spatial distribution, and TB-HIV co-infection-associated factors in an endemic scenario for TB in Northeastern Brazil. Methods An ecological and temporal series study was conducted based on secondary data obtained fr…
Tulane University
Pediatric tuberculosis (TB) continues to pose diagnostic challenges in low- and middle-income countries with high rates of TB disease, due to the well-described impact of paucibacillary disease in children, and current TB culture and polymerase-chain reaction tests are of limited…
PENTA Foundation
…ohorts within the same region are often similar in terms of epidemiology and treatment approaches), and region is then included as a covariate in the analysis. REGULATORY \& ETHICAL ISSUES COMPLIANCE EPPICC is an observational study with no study-specific interventions beyond th…
Mama M, Manilal A, Tesfa H, Mohammed H, Erbo E
…rome) pandemic. The AIDS virus has considerably reshape the epidemiology of TB by widening the risk of reactivating latent TB, increasing the possibility of TB infection once contracted to tubercle bacilli (re-infection) and by elevating the risk of rapid progression instantly af…
Gaensbauer J, Broadhurst R
Purpose of review Tuberculosis is leading cause of global morbidity and mortality and a significant proportion of the burden of disease occurs in children. In the past 5 years, a number of innovations have improved the diagnosis and treatment for children with both latent tubercu…
Parriott A, Kahn JG, Ashki H, Readhead A, Barry PM, et al.
Objective Targeted testing and treatment of persons with latent tuberculosis infection (LTBI) is a critical component of the US tuberculosis (TB) elimination strategy. In January 2016, the California Department of Public Health issued a tool and user guide for TB risk assessment …
Holtgrewe LML, Johnson A, Nyhan K, Boffa J, Shenoi SV, et al.
…al. More research is needed to explore the heterogeneous TB epidemiology in South Africa.
Gonzalez-Reyes R, Katz D, Lambert L, Sorri Y, Narita M, et al.
Background Latent tuberculosis infection (LTBI) screening and treatment interventions that are tailored to optimize acceptance among the non-U.S.-born population are essential for U.S. tuberculosis elimination. We investigated the impact of medical interpreter use on LTBI treatme…
Bergeron A, Mikulska M, De Greef J, Bondeelle L, Franquet T, et al.
…then conducted a meticulous review of the literature on the epidemiology, diagnosis, and management of LTBI, tuberculosis, and nontuberculous mycobacterial infections among patients in haematology, and we formulated clinical guidelines according to standardised European Conferenc…
Chauhan A, Parmar M, Dash GC, Solanki H, Chauhan S, et al.
Background & objectives The National Prevalence Survey of India (2019-2021) estimated 31 per cent tuberculosis infection (TBI) burden among individuals above 15 years of age. However, so far little is known about the TBI burden among the different risk groups in India. Thus, this…
Koeken VACM, Verrall AJ, Netea MG, Hill PC, van Crevel R
Background Some individuals, even when heavily exposed to an infectious tuberculosis patient, develop neither active nor latent tuberculosis infection (LTBI). This 'early clearance' of Mycobacterium tuberculosis is associated with a history of bacillus Calmette-Guérin (BCG) vacci…
Guo HY, Zhong QH, Zhou J, Zhao ZM, Zhang XL, et al.
Background China is one of the countries sharing the major burden of tuberculosis (TB) in the world. Health care workers (HCWs) are subject to a high risk of occupational latent tuberculosis infection (LTBI)-an asymptomatic state of TB disease. However, the heterogenic compositio…
Ferdosnejad K, Zamani MS, Soroush E, Fateh A, Siadat SD, et al.
Despite the fact that some cases of tuberculosis (TB) are undiagnosed and untreated, it remains a serious global public health issue. In the diagnosis, treatment, and control of latent and active TB, there may be a lack of effectiveness. An understanding of metabolic pathways can…
Assistance Publique - Hôpitaux de Paris
…more, thorough knowledge of a specific country's TB disease epidemiology is essential to map out a comprehensive national strategic plan for TB and could help identify determinants for unfavorable treatment outcome or loss to follow-up. The healthcare pathway of patients with tub…
McLean MR, Lu LL, Kent SJ, Chung AW
Mycobacterium tuberculosis ( Mtb ) resides in a quarter of the world's population and is the causative agent for tuberculosis (TB), the most common infectious reason of death in humans today. Although cellular immunity has been firmly established in the control of Mtb , there is …
Holzman SB, Perry A, Saleeb P, Pyan A, Keh C, et al.
Background Tuberculosis (TB) elimination within the United States will require scaling up TB preventive services. Many public health departments offer care for latent tuberculosis infection (LTBI), although gaps in the LTBI care cascade are not well quantified. An understanding o…
Ayelign B, Negash M, Genetu M, Wondmagegn T, Shibabaw T
… association between diabetes and tuberculosis, focusing on epidemiology, pathogenesis, and immune dysfunction in diabetes mellitus, and its association with susceptibility, severity, and treatment outcome failure to tuberculosis.
Lee YW, Chung H, Kim SH, Sung H, Ha SM, et al.
Purpose Liver transplant (LT) recipients have an increased risk of tuberculosis (TB), which is associated with higher mortality rates. This retrospective cohort study assessed the outcome and tolerability of screening and treatment of latent tuberculosis infection (LTBI) in LT re…
Antony BS, Nagarajan C, Thomas KE, Stephen SB, Yasam SK, et al.
Background The purpose of this meta-analysis is to verify that rs1861494 and rs2069718, two polymorphisms in the IFN-gene, are associated with tuberculosis (TB) infection in Asian populations. Methods To find appropriate case-control studies, a search was done from the databases,…
Gomes CMF, Terreri MT, Moraes-Pinto MI, Pinheiro MM
Background The reactivation rate of tuberculosis in patients with chronic inflammatory arthritis (CIA) on TNFα inhibitors (TNFi) and baseline negative screening for latent tuberculosis infection (LTBI) is higher than in the general population. Aim To compare the performance of tu…
Soriano-Arandes A, Caylà JA, Gonçalves AQ, Orcau À, Noguera-Julian A, et al.
Introduction Tuberculosis (TB) is a global infectious disease. In low-incidence countries, paediatric TB affects mostly immigrant children and children of immigrants. We hypothesize that these children are at risk of exposure to Mycobacterium tuberculosis when they travel to the …
Lu P, Xu J, Wang R, Gong X, Liu Q, et al.
Background The ESAT6-CFP10 (EC) skin test is recommended by the World Health Organization for latent tuberculosis infection (LTBI). However, it is still unknown how the EC skin test performs in students during a school tuberculosis outbreak. Methods We conducted an epidemiologica…
Reynolds G, Haeusler G, Slavin MA, Teh B, Thursky K
Purpose Contention surrounds how best to screen patients for latent and undiagnosed infection prior to cancer treatment. Early treatment and prophylaxis against reactivation may improve infection-associated morbidity. This study sought to examine rates of screening and prevalence…
Kwan PKW, Periaswamy B, De Sessions PF, Lin W, Molton JS, et al.
Background Current tools for diagnosing latent TB infection (LTBI) detect immunological memory of past exposure but are unable to determine whether exposure is recent. We sought to identify a whole-blood transcriptome signature of recent TB exposure. Methods We studied household …
Narsana N, Alejandra Pérez M, Subramanian A
This review describes the epidemiology and risk factors of tuberculosis (TB) in solid organ transplant recipients. We discuss the pre-transplant screening for risk of TB and management of latent TB in this population. We also discuss the challenges of management of TB and other d…