Showing 176–200 of 200 documents
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Rehmadanta Sitepu, Fira Dwijayanti, Chresiani Destianita Yoedistira
The conversion phase in tuberculosis treatment examines patients to ensure the possibility of further advancement. Despite its low specificity, microscopic evaluation is a standard method at public health centers. Moreover, the biased results from this method form a new problem r…
Ahmet Yılmaz, Dursun Erol Afşin
Objective: In the study, 419 Mycobacterium tuberculosis complex strains (MTC), which were isolated from samples sent to the Regional Tuberculosis Laboratory in our city between 2015 and 2019 with suspected tuberculosis from Erzurum and surrounding cities were investigated. Method…
Prommi A, Wongjarit K, Petsong S, Somsukpiroh U, Faksri K, et al.
Isoniazid-resistant tuberculosis (Hr-TB) is an important drug-resistant tuberculosis (TB). In addition to rifampicin, resistance to other medications for Hr-TB can impact the course of treatment; however, there are currently limited data in the literature. In this study, the drug…
Sanjida Bari Ananna, Sohidul Islam, Ishrat Jabeen, Ishtiaque Ahammad, S. M. Mostofa Kamal, et al.
Background: Multi-drug resistant (MDR) Tuberculosis (TB) is one of the most significant concerns in tuberculosis control. Genotyping of Mycobacterium tuberculosis helps study evolutionary relationships, its transmission, and molecular epidemiology. The collaborative data from gen…
Batool R, Khan SW, Imran M, Barry Z, Ali SZ
…e To determine the treatment outcomes of the drug-resistant tuberculosis patients who were previously exposed to second line drugs. Methods The retrospective study was conducted at eight Programmatic Management of Drug Resistant Tuberculosis (PMDT) sites in Sindh and Balochistan.…
World Health Organization
…panies the third edition of the WHO operational handbook on tuberculosis, Module 3: Diagnosis, and provides technical information sheets on selected rapid diagnostic technologies for the detection of tuberculosis (TB) and drug-resistant tuberculosis (DR-TB). The document describe…
Ntandazo Dlatu, Lindiwe Modest Faye, Teke Apalata
…t programs, especially in areas with limited re-sources, as tuberculosis continues to be a major public health issue. The study aimed to evaluate clinical data from TB-infected pa-tients' clinic files in rural areas of the Olivier Reginald Tambo District Municipality, Ea…
Yazısız H, Hırçın Cenger D, Yazısız V, Kılıç L, Altın S
Introduction Tuberculosis (TB) is continuing to be a important public health problem in the undeveloped countries. Drug sensitivity rate should be monitored for the effective treatment and control in the TB. The aim of this study was to determine the rate of resistance to first l…
Susan E Purchase, Joanna Brigden, James A Seddon, Neil A Martinson, Lee Fairlie, et al.
…BACKGROUND:** Young children have a high risk of developing tuberculosis (TB) disease following infection with Mycobacterium tuberculosis in the absence of preventive treatment. Infection prevalence and risk factors for infection impact delivery of prevention strategies. We aimed…
Diah Syafriani, Rouly Pola Pasaribu, Zen Ahmad
MDR TB is a condition of M. tuberculosis that is resistant to isoniazid and rifampicin. This occurs because of certain genomic mutations in certain Mtb specific genes. Some of the genes that play a role in the INH mutation are the katG gene, the inhA gene, the ahpC gene, the ndh …
D Gebretsadik, Naglaa Ahmed, Elias Kebede, Muneer Khan Mohammed, Belete MA
… Daniel Gebretsadik Email gebretsadikd@gmail.comBackground: Tuberculosis is a communicable disease that is a major cause of ill health, one of the top 10 causes of death worldwide, and the leading cause of death from a single infectious agent, even ranking above human immuno-defi…
Alagappan C, Sunil Shivekar S, Brammacharry U, Cuppusamy Kapalamurthy VR, Sakkaravarthy A, et al.
…s associated with INH resistance mutations in Mycobacterium tuberculosis in codon katG315 and in the promoter region of the inhA gene were investigated. Methods Sputum specimens of smear-positive tuberculosis (TB) patients were subjected to GenoType MTBDRplus assay to identify ka…
T. I. Guryeva, Е. И. Никишова, Olga A. Zolotaya, O. M. Sveshnikova, Д. В. Перхин, et al.
…tablish effectiveness and safety of preventive treatment of tuberculosis with fluoroquinolones in children exposed to multidrug-resistant tuberculosis (MDR TB) in their families. Subjects and Methods. A cohort prospective study was conducted in Arkhangelsk Region from January 01,…
Yan L, Niu X, Liang K, Guan F, Yu X, et al.
Background: Tuberculosis (TB) is the second largest infectious disease killer in China, and the increasing prevalence of drug-resistant TB patients complicates treatment efforts and raises associated costs. Research on the mechanisms and characteristics of drug-resistant TB contr…
Ahmad Alikhani, Elnaz Amini, Mohsen Arabi, Hamid Reza Goli
Abstract Background: Due to the significant prevalence of tuberculosis (TB) in Mazandaran and Golestan provinces in northern Iran, we aimed to investigate the gene mutations in resistant Mycobacterium tuberculosis isolated from pulmonary TB patients in these provinces of Iran. Me…
Mesfin EA, Beyene D, Tesfaye A, Admasu A, Addise D, et al.
Background Multidrug drug-resistant tuberculosis (MDR-TB) is a major health problem and seriously threatens TB control and prevention efforts globally. Ethiopia is among the 30th highest TB burden countries for MDR-TB with 14% prevalence among previously treated cases. The focus …
Olutayo Israel Falodun, Idowu Simeon Cadmus, O. E. Fagade
The success of the global tuberculosis (TB) control program has been threatened with drug resistant strains emergence; especially the Multidrug Resistant Tuberculosis (MDR-TB). Despite that Nigeria is one of the countries with high tuberculosis burden, little is known on the magn…
Ahamed, Nisha, Yurasova, Yelena, Zaleskis, Richard, Grzemska, Malgorzata, Reichman, Lee B, et al.
Tuberculosis is an increasingly serious problem in the WHO European region, particularly in the countries of eastern Europe, the Baltic States, and the Commonwealth of Independent States (CIS).Primary health care providers can play an important role in tuberculosis control throug…
Preeti Sharma, Alok Raina, Kavita Sharma
…o provide nutritional incentive of INR 500 per month to all tuberculosis (TB) patients till they complete their treatment. Aim of present study is to determine the number (proportion) of patients being treated for tuberculosis who received the benefits of NPY and to explore the wa…
Shi W, Jing Wu, Tan Q, Hu Cm, Xiang Zhang, et al.
… Province, People’s Republic of China; 2Department of Tuberculosis, The Second Hospital of Nanjing, Nanjing, Jiangsu Province, People’s Republic of China; 3Department of Tuberculosis, The Third Hospital of Zhenjiang City, Zhenjiang, Jiangsu Province, People’s Re…
Anubha Singh
Many people believe that tuberculosis (TB), like smallpox, is a disease of the past, and they are surprised to learn that tuberculosis still exists in the United States. On a global basis, TB continues to be the leading cause of death for adults from an infectious disease. Despit…
Arshad Javaid, Mazhar Ali Khan, Mukhtiar Zaman Afridi, Abdur Rab Khan, Abdul Ghafoor
…kground: Resistance to first-line drugs is a major issue in tuberculosis (TB) control. Globally 20% of previously treated TB cases have been reported to have multi-drug resistant tuberculosis (MDR-TB). Pakistan is among the top high TB burden countries with an annual incidence of…
Muhammad Bilal Ibrahim, Reyan Hussain Shaikh, Arshia Jahangir, Ali Husnain Khan, Hiba Noor
Tuberculosis is more frequently found among high-risk populations in the United States. It has a challenging diagnosis since it can present with diverse organ involvement that may delay the diagnosis. This is especially true regarding hepatic tuberculosis, with prevalence varying…
N H, P SR, Sura M, Daddam JR
Tuberculosis is the most dangerous disease causing maximum deaths than any other, caused by single infectious agent. Due to multidrug resistant of Mycobacterium tuberculosis strains, there is a need of new drugs and drug targets. In this work, we have selected RmlD (α-dTDP-6-deox…
Khalid Mokti, Zaleha Md Isa, Mohd Rizal Abdul Manaf, Firdaus Hayati, Syed Sharizman SYED ABD RAHIM
Undernutrition and tuberculosis (TB) are a vital issue in most developing countries of the world. Both of these medical problems tend to have interacted with each other and bidirectional. The undernutrition creates a more significant problem in patients with active TB rather than…