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Liang Y, Li X, Yang Y, Xiao L, Liang Y, et al.
…round About a quarter of the world's population with latent tuberculosis infection (LTBI) are the main source of active tuberculosis. Bacillus Calmette Guerin (BCG) cannot effectively control LTBI individuals from developing diseases. Latency-related antigens can induce T lymphoc…
Chin-Chung Shu, MD
To follow-up the latent tuberculosis infection and the risk of developing active tuberculosis in patients receiving long-term dialysis Tuberculosis (TB) remains an important infectious disease worldwide. Taiwan is still an edemic area. In 2008, there is an incidence of 62 person…
Bwarenaba B Kautu
Tuberculosis (TB) is a deadly infectious disease caused by Mycobacterium tuberculosis (M. tuberculosis). Currently, it is the leading infectious disease killer in the world ranking above HIV/AIDS. Furthermore, the continued emergence and spread of drug-resistant forms of TB are i…
Wang S, Wu J, Chen J, Gao Y, Zhang S, et al.
…n tests offer several advantages for the rapid diagnosis of tuberculosis (TB). The Mycobacterium tuberculosis-specific antibody responses associated with different stages of TB infection remain to be investigated. Methods The Pathozyme-Myco IgG (Myco G), Pathozyme TB Complex Plus…
Winglee K, Hill AN, Belknap R, Stout JE, Ayers TL
…ERON Gold In-Tube (QFT), are important diagnostic tools for tuberculosis infection, but little work has been done to study the performance of these tests in populations prioritized for tuberculosis testing in the United States, especially those other than health care personnel. M…
Kase AM, Libertin CR, Roy A
…anti-TNF pharmaceuticals increases the risk of reactivating tuberculosis making screening for latent tuberculosis infection (LTBI) a requirement prior to initiating therapy. Case A middle-aged male from China with a past medical history of LTBI and Crohn's disease, previously on …
Carlos Brito, Rita Moraes de Brito
…he article "Brazilian Recommendations for the Management of Tuberculosis Infection in Immune-Mediated Inflammatory Diseases" by Viviane de Souza et al. presents important discussions on the subject; however, the recommendation for annual repetition of the TST/IGRA test for three …
Charutha Retnakumar, Komala Ezhumalai, Ruben Raj, Prakash Babu Narasimhan, Subitha Lakshminarayanan, et al.
Introduction: Tuberculosis control remains an ongoing challenge for low and middle-income countries with lack of understanding of the factors determining transmission of infection. This study aimed to investigate the impact of alcohol use among pulmonary tuberculosis patients on …
He J, Fan Y, Shen D, Yu M, Shi L, et al.
Background Tuberculosis (TB) is an infectious disease and its mortality rate ranks first. Latent tuberculosis infection (LTBI) means that a patient is infected with Mycobacterium tuberculosis, but has no relative clinical symptoms. It has been estimated that approximately 10% of …
Stockbridge EL, Miller TL, Carlson EK, Ho C
…Targeted identification and treatment of people with latent tuberculosis infection (LTBI) are key components of the US tuberculosis elimination strategy. Because of recent policy changes, some LTBI treatment may shift from public health departments to the private sector. Objectiv…
Chin-Chung Shu, MD
To follow-up the latent tuberculosis infection and evaluate the risk of developing active tuberculosis in patients with severe chronic kidney disease or receiving long-term dialysis Tuberculosis (TB) remains an important infectious disease worldwide. Taiwan is still an edemic ar…
Herrera M, Keynan Y, López L, Marín D, Arroyave L, et al.
…f liberty (PDL) are at high risk of acquiring Mycobacterium tuberculosis infection (latent tuberculosis infection [LTBI]) and progressing to active tuberculosis (TB). We sought to determine the incidence rates and factors associated with LTBI and active TB in Colombian prisons. U…
Gaensbauer J, Aiona K, Haas M, Reves R, Young J, et al.
…ve the highest age-specific rate of progression from latent tuberculosis infection (LTBI) to active disease. Therefore, regimens for treatment of pediatric LTBI must be not only efficacious but practical enough to overcome the unique childhood barriers to regimen adherence. Since…
Araujo Z, de Waard JH, Camargo M, Lopez-Ramos JE, de Larrea CF, et al.
Diagnosis and treatment of active tuberculosis (ATB) as well as latent tuberculosis infection (LTBI) are required for effective tuberculosis (TB) control, especially in TB endemic area. The usefulness of conventional tests to distinguish between ATB and LTBI has remained challeng…
Alebouyeh S, Weinrick B, Achkar JM, García MJ, Prados-Rosales R
Tuberculosis (TB) is a global disease caused by Mycobacterium tuberculosis ( Mtb ) and is manifested as a continuum spectrum of infectious states. Both, the most common and clinically asymptomatic latent tuberculosis infection (LTBI), and the symptomatic disease, active tuberculo…
Xiao Xiao, Zhipeng Li, Jing Chen, Xin Shen
**BACKGROUND:** Students represent a key demographic for tuberculosis (TB) control in China. This study utilizes a dynamic Markov model to forecast the epidemiological trends of active tuberculosis (ATB) among students in Shanghai through 2035 and evaluate the effectiveness of di…
Khayat M, Fan H, Vali Y
…this culminated in a microbiological diagnosis of pulmonary tuberculosis. The patient's daughter had been treated for tuberculosis two years earlier and unfortunately family screening for latent TB was not undertaken. This case appears to confirm the concerns that the CD4 + T-cel…
Liu J, Li Y, Liu T, Shi Y, Wang Y, et al.
Background Mycobacterium tuberculosis (Mtb) survives inside a human host for a long time in the form of latent tuberculosis infection (LTBI). Latent infection of tuberculosis has the opportunity of developing into active tuberculosis (ATB), which has greatly endangered human heal…
Bintang Yinke Magdalena Sinaga, Jelita Siregar, Delores Elisabeth Sormin, Rina Sundari, Yoseph Leonardo Samodra
…TIVE:** The WHO advises the detection of cases of pulmonary tuberculosis (TB) in household contacts (HHCs). This activity allows for testing family members of TB patients for latent tuberculosis infection (LTBI) and detecting factors associated with LTBI. The purpose of this stud…
Saadiq Garba, Heidi Fischer, Lei Qian, Zhuoxin Li, Katia Bruxvoort, et al.
…ract Background California has the largest number of active tuberculosis (TB) cases in the US; more than 2 million Californians are estimated to have latent tuberculosis infection (LTBI), and 87% of TB cases in 2021 were attributed to LTBI reactivation. This study in a large Cali…
Namuganga AR, Nsereko M, Bagaya BS, Mayanja-Kizza H, Chegou NN
…ckground There is a need for new tools for the diagnosis of tuberculosis (TB) amongst patients who present at primary health care centers with symptoms suggestive of TB. Objectives To assess the abilities of selected blood-based host biomarkers to discriminate between patients wh…
Thomaz Felipe Soares Arnizant, Filipe Andrade Bernardi, Tiago Lara Michelin Sanches, Nathalia Yukie Crepaldi, Thiago Nascimento do Prado, et al.
According to the World Health Organization (WHO), latent tuberculosis occurs through latent infection by Mycobacterium tuberculosis without evidence of active tuberculosis (TB) symptoms. As patients don’t develop the same symptoms as active TB, the treatment is abandoned before t…
Yu Q, Yan J, Tian S, Weng W, Luo H, et al.
…n clinical metrics to discriminate between active pulmonary tuberculosis (APTB) and inactive pulmonary tuberculosis (IPTB). Patients and methods A total of 1096 patients with pulmonary tuberculosis (PTB) admitted to Wuhan Jinyintan Hospital between January 2017 and December 2019 …
Ebru Yalçın, Nagehan Emiralioğlu, Gökçen Dilşa Tuğcu, Sanem Eryılmaz, Mina Hızal, et al.
… there is strong evidence of its role in the development of tuberculosis(Tb) disease. Our aim is to determine the levels of vitamin D, cathelicidin B(LL-37) in patients with Tb disease, latent Tb infection(LTBI) and healthy children. Our second aim of this study is to determine t…
VanValkenburg A, Kaipilyawar V, Sarkar S, Lakshminarayanan S, Cintron C, et al.
Background Most individuals exposed to Mycobacterium tuberculosis (Mtb) develop latent tuberculosis infection (LTBI) and remain at risk for progressing to active tuberculosis disease (TB). Malnutrition is an important risk factor driving progression from LTBI to TB. However, the …