Showing 151–175 of 200 documents
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Afshan Ali Shaik, Uday C. Kakodkar, Cigy Borges
Introduction: Diagnosis of sputum negative pulmonary tuberculosis can be challenging and time consuming, with many patients being put on empirical anti-tuberculosis treatment. Bronchoscopy helps in early diagnosis in such patients. Aims and Objectives: To assess the diagnostic ut…
…help in discrimination of two closely related Mycobacterium tuberculosis and M.bovis. Here, we analyzed 24 M. bovis, 39 M. tuberculosis, 21 fresh acid-fast positive sputum samples and standardmycobacterial strains with pncA, 12.7 Kb and IS6100 based PCR assays. DNA from cultures …
Richard G White, Gavin J Churchyard, Katherine C Horton, Andrew Fiore-Gartland, Marcel A Behr, et al.
Current licensure trials of new vaccines to prevent tuberculosis disease use bacteriologically confirmed symptomatic tuberculosis disease as the primary endpoint. Globally, the incidence of symptomatic tuberculosis disease is low, making licensure trials large, long, and expensiv…
Li QH, Zhang Y, Zhao MM, Gu Y, Hu Y, et al.
…eous application and testing method to detect Mycobacterium tuberculosis rRNA (SAT-TB) with the endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) biopsy specimens to differentiate sputum-negative tuberculosis from sarcoidosis. In the first part, we vali…
Larissa Gorbach
Children from families with pulmonary tuberculosis have the highest risk for tuberculosis. The objective of this study was to research of 230 cases of tuberculosis in children from contact with relatives affected by tuberculosis. <b>Patients:</b> The analyzed group included 153 c…
Sari NIP, Mertaniasih NM, Soedarsono, Maruyama F
…nd accurate diagnosis are very important in managing active tuberculosis because they provide an advantage in preventing further disease transmission. In accordance with the recommendation of the World Health Organization, the Indonesian Tuberculosis Control Program uses the acid…
Rajamanickam A, Ann Daniel E, Dasan B, Thiruvengadam K, Chandrasekaran P, et al.
Background The progression from Mycobacterium tuberculosis infection to active tuberculosis disease varies among individuals, and identifying biomarkers to predict progression is crucial for guiding interventions. In this study, we aimed to determine plasma immune biomarker profi…
Farimah Yarmohammadi, Ali Farhadi, Narges Hassanaghaei, Gholamreza Rafiei Dehbidi, Farzaneh Zarghampoor, et al.
Background: Pulmonary tuberculosis is currently diagnosed using traditional techniques, such as smear production from sputum samples, to detect acid-fast bacilli (AFB) and bacteriological culture. The detection of Mycobacterium tuberculosis DNA in peripheral blood samples could p…
О. Е. Русских, E. V. Savintseva, D.А. Kudlаy, N. P. Doktorovа, P. G. Sysoev
…eople in the world are infected with the causative agent of tuberculosis. A priority task in the diagnosis of tuberculosis infection is the use of accurate, accessible and scalable tools. The tuberculin skin test (TST), or Mantoux test, and the interferon gamma release assay (IGR…
E. I. Afanasyev, A. Mymrina, Z. R. Nabiullina, T. V. Buzanakova
Introduction. Infiltrative pulmonary tuberculosis is a localized form of tuberculosis, in some cases preceding more common and prognostically unfavorable forms of tuberculosis. With this disease, there are no absolute specific signs in the clinical and radiological picture, which…
Seifert M, Vargas E, Ruiz-Valdepeñas Montiel V, Wang J, Rodwell TC, et al.
Outside of the ongoing COVID-19 pandemic, tuberculosis is the leading cause of infectious disease mortality globally. Currently, there is no commercially available point-of-care diagnostic that is rapid, inexpensive, and highly sensitive for the diagnosis of active tuberculosis d…
Jenti Sitorus
Pulmonary tuberculosis is an infectious disease that attacks the lungs which is typically characterized by the formation of granulomas causing tissue neocrosis. Pulmonary tuberculosis is caused by "mycrobacterium tuberculosis" a type of rod-shaped germ with a length of 1-4 / mm a…
Ehlers LP, Bianchi MV, Argenta FF, Lopes BC, Taunde PA, et al.
Tuberculosis is a common zooanthroponosis in humans with a high incidence in Brazil, but it may also affect non-human primates (NHPs), of which Old World primates are most commonly involved. Nonetheless, its occurrence in New World primates is unknown, and therefore, this study a…
Poudyal IP, Khanal P, Mishra SR, Malla M, Poudel P, et al.
…e co-morbidity of cardiometabolic diseases in patients with Tuberculosis adds a significant burden in current health systems in developing countries including Nepal. The main objective of this study was to explore cardiometabolic risk factors among patients with Tuberculosis. Met…
Kanabalan RD, Lee LJ, Lee TY, Chong PP, Hassan L, et al.
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria encompassing nine members of closely related species that causes tuberculosis in animals and humans. Among the nine members, Mycobacterium tuberculosis (M. tuberculosis) remains the main causative agent f…
Rachmad Bayu Kuncara, Dewina Zumrotin Najiah
Pulmonary tuberculosis is an infectious disease caused by infection with the bacteria Mycobacterium tuberculosis. Patients diagnosed with pulmonary tuberculosis will receive Anti-Tuberculosis Drug (OAT) therapy for six months. In the first two months or what is called the intensi…
М. С. Опанасенко, I. V. Liskina, V. I. Lysenko, Л. М. Загаба, O. V. Tereshkovich, et al.
…S WITH DETERMINATION OF DEGREE OF MORPHOLOGICAL ACTIVITY OF TUBERCULOSIS AND CLINICAL PRESENTATION OF TUBERCULOSIS PATIENTS AFTER VATS RESECTION AND VATS PLEUROECTOMY WITH DECORTICATION OF LUNG M. S. Opanasenko, I. V. Liskina, V. I. Lysenko, L. M. Zagaba, O. V. Tereshkovich, B. M…
Burke RM, Nliwasa M, Dodd PJ, Feasey HRA, Khundi M, et al.
Background Tuberculosis case-finding interventions are critical to meeting World Health Organization End TB strategy goals. We investigated the impact of community-wide tuberculosis active case finding (ACF) alongside scale-up of human immunodeficiency virus (HIV) testing and car…
Dyah Aryani Perwitasari, Muh. Deni Kurniawan, Lalu Muhammad Irham, Imaniar Noor Faridah, Triantoro Safaria, et al.
Until presently, tuberculosis has been a burden to Indonesia, placing the country third among countries with the heaviest tuberculosis burden in the world. Tuberculosis treatment takes a long period and may cause side effects. Therefore, it requires sufficient tuberculosis knowle…
Tornheim JA, Madugundu AK, Paradkar M, Fukutani KF, Queiroz ATL, et al.
…kground Gene expression profiling is emerging as a tool for tuberculosis diagnosis and treatment response monitoring, but limited data specific to Indian children and incident tuberculosis infection (TBI) exist. Methods Sixteen pediatric Indian tuberculosis cases were age- and se…
Noubiap JJ, Nansseu JR, Nyaga UF, Nkeck JR, Endomba FT, et al.
…d poor glycaemic control significantly increase the risk of tuberculosis and adversely affect tuberculosis treatment outcomes, the global burden of diabetes in the context of tuberculosis remains unknown. We did a systematic review and meta-analysis to estimate the prevalence of …
Gezahegn LK, Argaw E, Assefa B, Geberesilassie A, Hagazi M
…amide has proved to be highly effective in the treatment of tuberculosis (TB). However, the most common adverse effect of this regimen leading to interruption of therapy is hepatotoxicity. There is a paucity of evidence in Tigray region on anti-tuberculosis drug-induced hepatitis…
Abebaw Getachew, Tadesse Guadu, Araya Mengistu, Mebrat Ejo, Abebe Belete, et al.
Abstract Introduction: Tuberculosis is among infectious diseases that disproportionally affect low-income populations of the world. Intimacy of cattle and humans may play a role in the transmission of tuberculosis between man and animals. There is scarce information on risk facto…
Angella Musiimenta, Wilson Tumuhimbise, Esther C. Atukunda, Aaron Mugaba, Sebastian Linnemayr, et al.
…ies (DATs), such as real-time monitors and SMS reminders in tuberculosis medication adherence, suboptimal patient engagement with various DATs has been reported. Additionally, financial constraints can limit DAT’s utility. The perceived usefulness and the design mechanisms of DAT…
Berihun YA, Nguse TM, Gebretekle GB
Background Prevalence of tuberculosis in vulnerable groups such as prisoners is usually high, and the problem is worsened by poor treatment outcomes. In spite of this, there is limited information regarding tuberculosis in prisons of Ethiopia. Hence, this study was aimed to asses…