Showing 151–175 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Fairuz Fairuz, Hasna Dewi
Extrapulmonary tuberculosis (EPTB), which accounts for 10%–40% of the global burden of TB, is strongly associated with human immunodeficiency virus infection. Diagnosing EPTB is challenging, and recently, there has been a concerted effort to evaluate the latest molecular diagnost…
Araújo RM, Montenegro RA, Peixoto ADS, Silva LLS, da Costa RMPJ, et al.
Background The diagnosis of extrapulmonary tuberculosis (EPTB) shows numerous difficulties because of non-specific symptomatology and low sensitivity of conventional methods. Loop-mediated isothermal amplification (LAMP) is a fast and low-cost technique, which can amplify under i…
Chekesa B, Singh H, Gonzalez-Juarbe N, Vashee S, Wiscovitch-Russo R, et al.
Background The lineage 4 (L4) of Mycobacterium tuberculosis (MTB) is not only globally prevalent but also locally dominant, surpassing other lineages, with lineage 2 (L2) following in prevalence. Despite its widespread occurrence, factors influencing the expansion of L4 and its s…
Niu T, Li Y, Ru C, Chen A, Shi Y, et al.
…risk factors, and complication characteristics of pulmonary tuberculosis (PTB) combined with extrapulmonary tuberculosis (EPTB) in elderly patients (aged > 60 years). Clinical data were collected from pathogen positive elderly patients with PTB hospitalized in a teaching hospital…
Sevilla-Fuentes S, Mendoza-Vargas LÁ, Araiza-Rodríguez JF, Berthaúd-González B, Falfán-Valencia R, et al.
…l cavity was requested, confirming the diagnosis of lingual tuberculosis, an extremely rare disease, occurring in less than 1% of extrapulmonary cases. MRI of the cervical spine showed a crush fracture of the C6 and C7 bodies associated with spondylitis of probably infectious eti…
Lan Y, Chen L, Zhang H
Extrapulmonary tuberculosis (EPTB) accounted for 14% of 6.4 million cases of TB that were reported to WHO in 2017, and genitourinary TB (GUTB) is the second most common type of EPTB. The most common site of GUTB is the kidneys and testicular TB is relatively rare. The case of one…
Noor AM, Ghazali SM, Bakar ZA, Ruzan IN
…ostic tools are critically needed to diagnose Mycobacterium tuberculosis and rifampicin resistance in AFB smear-negative samples. In this study, we evaluated the diagnostic performance of Xpert MTB/RIF Ultra (Ultra) as a rapid test to diagnose tuberculosis in smear-negative cases…
Shrinivasa B. Marinaik, Sriram Selvaraju, R. Srinivasan, Krishnamoorthy, Sunil Kumar Raina, et al.
…o roughly over half a million cases. Meanwhile the National tuberculosis elimination programme has made coordinated efforts to involve public and private health providers in accelerating TB notification. Government medical colleges which are tertiary care centres act as important…
Atherton RR, Cresswell FV, Ellis J, Skipper C, Tadeo KK, et al.
…ion recommended the Xpert ® MTB/RIF Ultra assay (Ultra) for tuberculosis (TB) diagnosis. Ultra offers improved analytical sensitivity when compared with the initial Xpert ® MTB/RIF (Xpert) assay for the detection of Mycobacterium tuberculosis. Ultra is therefore likely to be of p…
İlkay Bahçeci
Aim: Despite the developments every passing year, tuberculosis is still a major public health problem in Turkey and in the world. Early and correct diagnosis is important for the control of the disease. The aim of this study is to investigate the diagnostic efficiency of the cult…
Varghese B, Enani M, Alrajhi A, Al Johani S, Albarak A, et al.
…ckground Growing evidences suggested that the Mycobacterium tuberculosis complex (MTBC) lineages can determine the clinical outcome of pulmonary and extra-pulmonary tuberculosis. However, limited data only available revealing such association of bacterial genotypes and clinical p…
Fang Y, Zhou Q, Li L, Zhou Y, Sha W
…udy aimed to investigate the epidemiology of extrapulmonary tuberculosis (EPTB) and analyse the epidemiological characteristics of EPTB patients with or without pulmonary tuberculosis (PTB). EPTB cases admitted in our hospital from January 2015 to December 2020 were included. Uni…
Venus Marie R Rojas, Michaela Zwyer, Selim Bouaouina, Daniela Brites, Sonia Borrell, et al.
The Mycobacterium tuberculosis complex (MTBC) phylogenetic lineages 1-4 (L1-L4) are the main causes of human tuberculosis (TB). Until now, most of the focus in the TB field has been on MTBC L2 and L4, as these two lineages are geographically widespread and have been repeatedly as…
Anil Kumar Gupta, Amit Singh, Saumya Srivastava, Arti Shrivas, Anvita Gupta Malhotra, et al.
Objectives: Tuberculosis (TB) is curable if diagnosed correctly and promptly. However, the lack of effective and accessible point-of-care tests hindered the systematic screening of TB. The current TB diagnostic methods, including molecular tests, have failed to deliver the capaci…
Wenting J, Yuyan M, Qingfeng S, Yao Z, Yumeng Y, et al.
Background and purpose abdominal tuberculosis (TB) is a common form of extrapulmonary TB but it is still a diagnostic dilemma in clinical practice. This study aimed to highlight the clinical features and diagnostic approaches for abdominal TB. Methods seventy cases of diagnosed a…
Santhanam Naguthevar, Deepak Kumar, Akshatha Ravindra, Subhashree Samantaray, Sarika Kombade, et al.
Abstract Background Extrapulmonary tuberculosis (EPTB) is quite prevalent in India, ranging from 8.3% and 13.1%. Diagnosis of EPTB is often challenging as it resembles other granulomatous conditions pathologically. TB culture remains the gold standard for definitive diagnosis, bu…
van Heerden JK, van Zyl A, Schaaf HS, Frigati LJ, Goussard P, et al.
Background Tuberculosis (TB) and childhood cancers have overlapping presentations and malignancies may be misdiagnosed as TB in high TB-burden settings. Methods This retrospective study investigated the diagnosis of TB in children with cancer registered in the Tygerberg Hospital …
Badr Aljarallah
Objective: Intestinal tuberculosis (ITB) is an important form of extrapulmonary TB that often mimics other gastrointestinal diseases, making early diagnosis and management challenging. This study aimed to assess the clinical features, diagnostic approaches and treatment response …
Ule Belotti NC, Madela NK, Tonelli Nardi SM, Mariano DC, de Souza NG, et al.
Background The Xpert Mycobacterium tuberculosis Rifampicin (MTB-RIF) is a technological innovation that presents precision and speed in the diagnosis of tuberculosis (TB). The study aimed to evaluate the performance of Xpert MTB/RIF in the TB diagnosis and compare its results wit…
Niu T, He F, Yang J, Ma C, Xu J, et al.
Background Pulmonary tuberculosis (PTB) complicated with extrapulmonary tuberculosis (EPTB) infection can aggravate the disease, but there have been few reports. Methods Retrospective analysis was used to collect the clinical data of PTB patients with pathogen positive in a teach…
Rashmi M. Karigoudar, Mahesh H. Karigoudar, Sanjay M. Wavare, Lakshmi Kakhandki, Smitha Bagali
Objective: Tuberculosis is an airborne infection caused by Mycobacterium tuberculosis. Timely diagnosis and treatment are important to prevent the spread of infection. Cartridge-based nucleic acid amplification test (CBNAAT) provides a valuable tool in the early detection of TB. …
Nikita Birhman, Nikhil Payal, Manisha Khandait, Mohit Bhardwaj
Abstract Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis , primarily affecting the lungs. While pulmonary TB (PTB) is the most prevalent form, comprising the majority of cases, extrapulmonary TB (EPTB) presents unique diagnostic and the…
Hoel IM, Syre H, Skarstein I, Mustafa T
The diagnosis of extrapulmonary tuberculosis (EPTB) is often challenging due to paucibacillary nature of the disease. Xpert MTB/RIF Ultra (Ultra) has been developed to improve detection of Mycobacterium tuberculosis complex (MTC) in paucibacillary specimens. The objective of the …
Rakhee Khanduri, Amita Mason, Varuna Jethani, Ankit Aggarwal, Sushant Khanduri, et al.
Tuberculosis (TB) is a major health concern. It is a contagious disease caused by Mycobacterium tuberculosis. The disease can present in almost all sites-pulmonary and extrapulmonary. We always consider TB in our differentials. The commoner presentations are picked up early and t…
Shivanand Gundalli, Surekha U Arakeri
A BSTRACT Background: Extrapulmonary tuberculosis (EPTB) was underdiagnosed due to its varying and nonspecific symptoms and limited diagnostic tools. Recent data suggest that there is an increase in the incidence of EPTB due to the availability of the newer diagnostic tools. Obje…