Showing 151–175 of 200 documents
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Wen J, He JQ
Purpose The influence of pregnancy on tuberculosis (TB) has not been well studied. This study aimed to investigate the demographics, clinical characteristics and outcomes of pregnant-related TB compared with the general population with TB. Methods We retrospectively analysed medi…
Ekaterina V Kurbatova, William C Whitworth, Kia E Bryant, Meredith G Dixon, Kelly E Dooley, et al.
…) treatment compared with the standard regimen. We analyzed pregnancy outcomes of women who became pregnant during the study. Among 740 women, 97 (13.1%) became pregnant. Of 102 pregnancies (in 97 participants), 30 (29.4%) participants were exposed to study drugs. Fetal loss…
Hughes JA, Pinilla M, Brooks KM, Eke AC, Stek A, et al.
…quinolones, but data on long-term exposure during and after pregnancy are limited. We examined the pharmacokinetics and safety of levofloxacin in an observational cohort of pregnant and postpartum women receiving treatment for RR-TB. Methods Participants were enrolled in their se…
Pop LG, Bacalbasa N, Suciu ID, Ionescu P, Toader OD
Tuberculosis (TB) in pregnancy is not only a matter of the past; it is also a current problem. These days, TB appears through mass migration and tourism in countries where it was believed that this condition is eradicated. Adequate knowledge about the medical history of patients,…
Sharon Sawe, Lufina Tsirizani, Richard Court, Kamunkhwala Gausi, Asanda Poswa, et al.
…is (RR-TB). There are limited data describing the effect of pregnancy on the pharmacokinetics of levofloxacin. We aimed to characterize the pharmacokinetics of levofloxacin in adults with RR-TB, including the effect of pregnancy. We pooled data from two studies conducted in adult…
M Zhou, X Han, L Jiang
…use of maternal mortality. In vitro fertilization and early pregnancy can reactivate latent TB due to altered cellular immunity. Tuberculosis-related acute respiratory distress syndrome (TB-ARDS) is rare but carries a mortality rate of 60-90%. Extracorporeal membrane oxygenation …
Curcio AM, Shekhawat P, Reynolds AS, Thakur KT
Neurologic infections during pregnancy represent a significant cause of maternal and fetal morbidity and mortality. Immunologic alterations during pregnancy increase the susceptibility of the premature brain to damage. This chapter summarizes the epidemiology, pathophysiology, an…
Shiu JR, Min A, Kiang TKL
…able data on the use of anti-tuberculosis (TB) drugs during pregnancy, with a focus on treatment outcomes, safety, and pharmacokinetics. This qualitative, narrative review was based on literature searches in Medline, Pubmed, Embase, and Google Scholar (from their inception to 13 …
Alene KA, Jegnie A, Adane AA
… to examine the impact of MDR-TB and its medications during pregnancy on maternal and perinatal outcomes. Search strategy PubMed, Scopus and Web of Science databases were searched from earliest to February 2020. Selection criteria Records were screened based on pre-defined select…
Daniela Vinueza, David E Rebellón-Sánchez, Maria Alejandra Recio, Ana Maria Granados, Luis Alberto Escobar, et al.
…sents the case of a 22-year-old woman at 29 weeks of pregnancy, who exhibited recent onset neurologic symptoms including paresthesia of the right side of the face, involuntary myoclonic movements in the ipsilateral hand, 1 week of weakness in the right side of the b…
Mark Mirochnick, MD
… (ARV) and anti-tuberculosis (TB) drugs administered during pregnancy and postpartum. This study will evaluate the pharmacokinetic (PK) properties of antiretroviral (ARV) and anti-tuberculosis (TB) drugs administered during pregnancy and postpartum. IMPAACT 2026 is a Phase IV o…
Nachega JB, Sam-Agudu NA, Budhram S, Taha TE, Vannevel V, et al.
… of data on SARS-CoV-2 infection and associated COVID-19 in pregnancy. Given the endemicity of infections such as malaria, HIV, and tuberculosis (TB) in sub-Saharan Africa (SSA), it is important to evaluate coinfections with SARS-CoV-2 and their impact on maternal/infant outcomes…
Uduak Okomo, Esin Nkereuwem, Hannah Blencowe, Aduragbemi Banke‐Thomas, Toyin Togun
An overlooked burden: Tuberculosis during pregnancy and postpartum continues to be under-recognised worldwide, despite bridging two major global health priorities: tuberculosis control and maternal and newborn survival. Recent estimates suggest that approximately 239,000 women co…
Alison J. Morton, Alexandra Roddy Mitchell, Richard E. Melville, Lisa Hui, Steven Y. C. Tong, et al.
Abstract Pregnancy may be associated with risk of developing tuberculosis (TB) in those infected with Mycobacterium tuberculosis ( Mtb ). The perinatal period could provide opportunities for targeted screening and treatment. This study aims to synthesise published literature on M…
Adriana Weinberg, Lisa Aaron, Grace Montepiedra, Timothy R. Sterling, Nahida Chaktoura, et al.
…, suggesting transient suppression of IFNg responses during pregnancy. Responses to the mitogen-positive QGIT kit control were absent in 60 (7%) women AP, 116 (16%) at L&D, but only 3 (0.4%) PP (P < 0.01), supporting the notion of transient immune suppression during pregna…
Irene Sinta Febriana, Sayugo Atikah, Sri Pudyastuti
…ory and also cardiovascular complication. Its occurrence in pregnancy is uncommon but is highly associated with higher mortality and morbidity for both maternal and fetal.Case Report: We report a case of 24 year old primigravida in National Respiratory Center Hospital, diagnosed …
Irene Sinta Febriana, Sayogo Atikah, Sri Pudyastuti
…ory and also cardiovascular complication. Its occurrence in pregnancy is uncommon but is highly associated with higher mortality and morbidity for both maternal and fetal. Case Report : We report a case of 24 year old primigravida in National Respiratory Center Hospital, diagnose…
Jiane Queliza Felipe Francia, Mariel Salazar Nevado-Gammad
…atogenous spread of Mycobacterium tuberculosis (MTb). Since pregnancy-related TB lacks the typical respiratory symptoms, clinicians might overlook the condition, complicating early diagnosis and treatment. This is a case of a 39-year-old multigravida, who presented with vaginal b…
P Seng, J R E Vintch
…duction Tuberculosis (TB) can be a challenging diagnosis in pregnancy as symptoms often overlap with normal pregnancy changes. Identifying risk factors can aid in timely diagnosis to initiate treatment and reduce mortality. Case summary A 40-year-old G2P0202 female from Mexico wi…
A. Priya, Patil N Ravi
Tuberculosis (TB) in pregnancy is a major health problem which possess a sustainable risk of morbidity to mother and fetus if not diagnosed and treated at correct time. The diagnosis in pregnancy is challenging, especially in the absence of lung involvement. It usually mimics oth…
JM Joshi, Banumathy Srikant, Srikant Balasubramaniam, Trimurti Nadkarni
… deformity and neurological deficits. Its occurrence during pregnancy is uncommon, presenting diagnostic and therapeutic challenges due to the dual imperative of maternal neurological preservation and fetal safety. We report the case of a 25-year-old woman at 30 weeks of gestatio…
Rosie Burton
… immunodeficiency virus (HIV), tuberculosis, and malaria in pregnancy. The global roll-out of antiretroviral therapy has significantly improved survival for people living with HIV and reduced mother-to-child transmission, but HIV infection remains a leading cause of maternal mort…
Alajaji NM, Sallout B, Baradwan S
…nosed with tuberculous spondylitis, or Pott disease, during pregnancy. CASE REPORT A 27-year-old female, in her first pregnancy and at 29 weeks of gestation, presented to the Emergency Department with worsening severe neck and back pain for the past 5 months. Post-gadolinium cont…
Song Y, Wang Z, Hao Z, Li L, Lu J, et al.
… is a rare severe clinical syndrome. HLH manifesting during pregnancy has been paid much attention in recent years. Despite the specificity of pregnancy-related HLH, there has not been any consensus regarding its treatment. According to a previous study, corticosteroid/IVIG is th…
Nalini Bala Pandey
Pregnancy with Tuberculosis (TB) can adversely affect the health of the gravida, foetus, and neonate with a spectrum of short and long-term implications. Prevention, diagnosis, and management with a multi-disciplinary team (MDT) approach of TB in pregnancy can improve maternal an…