Showing 151–175 of 200 documents
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Lichao Fan, Bo Guan, Moxin Cheng, Chang Liu, Yao Tian, et al.
…st; Chang Liu,3 Yao Tian,1 Ran Li,1 Yu Chen1 1Department of Tuberculosis, Shenyang Tenth Peopleâs Hospital, Shenyang Chest Hospital, Shenyang, Liaoning Province, 110044, Peopleâs Republic of China; 2Geriatric Cardiology Department of the Second Medical Center & Nation…
Kalra A, Parija D, Raizada N, Sachdeva KS, Rao R, et al.
Background Diagnosis of TB in pediatric population poses several challenges. A novel initiative was implemented in several major cities of India aimed at providing upfront access to free-of-cost Xpert MTB/RIF to presumptive pediatric TB cases. This paper aims to describe the expe…
Osorio N, Reyes MM
Tuberculosis is one of the most common infectious diseases around the world. With timely diagnosis and treatment, mortality in children is practically zero. It is usually associated with a diverse number of complications that can cause significant morbidity and mortality, such as…
Cristina Liscinscaia, Stela Kulciţkaia, Constantin Iavorschi, Iulia Ghimisli, Igor Ivanes
The problem of diagnostic errors of pediatric TB persists throughout the world and in the Republic of Moldova, the main causes being the peculiarities of evolution and polymorphism of the clinical manifestations of primary TB. The COVID-19 pandemic had a negative impact on the de…
Daniel Capellán-Martín, Juan J Gómez-Valverde, Ramón Sánchez-Jacob, Alicia Hernanz-Lobo, H Simon Schaaf, et al.
Tuberculosis (TB) remains a major global health burden, particularly in low-resource, high-prevalence regions. Pediatric TB diagnosis poses challenges with non-specific symptoms and less distinct radiological manifestations than adult TB. Many affected children remain undiagnosed…
AE Galvis, B Batoczki, IS Pecson, Children’s Lung Specialists, Las Vegas, Nevada, USA, T. F. Sellers, et al.
Tuberculosis (TB) remains the leading cause of death from a single infectious agent. Among children, TB can have a wide range of non-specific clinical and radiological manifestations becoming a challenging diagnosis, particularly in areas with a low prevalence. We present the cas…
Shivanand Prabhunatti, Aravind Karinagannanavar, Jagadish Gaddeppanavar
…Organization (WHO) declared a state of global emergency for tuberculosis (TB), due to the steady increase of the disease worldwide. India is the highest TB burden country accounting for one fifth (21%) of the global incidence. Objectives were to study: 1) average delay in diagnos…
Юлия Анатольевна Яровая, M. E. Lozovskaya, Anna Mosina, E. B. Vasilyeva, Л. В. Клочкова, et al.
…day, generalized forms are rarely found in the structure of tuberculosis in children. A significant risk factor for the development of generalized lesions is prolonged contact with a tuberculosis patient. The diagnosis of a specific etiology is often complicated by the absence of…
О. Е. Русских, N.Yu. Nikolenko
Ocular tuberculosis is a serious disease with a long recurrent course, often leading to a significant decrease in the visual functions and quality of life of patients as well as disability. In recent years, the incidence rate of the ocular tuberculosis in the Russian Federation h…
Daniel Capellán-Martín, Juan J. Gómez-Valverde, Ramon Sanchez, David Bermejo-Peláez, Lara García-Delgado, et al.
Tuberculosis (TB) is still considered a leading cause of death and a substantial threat to global child health. Both TB infection and disease are curable using antibiotics. However, most children who die of TB are never diagnosed or treated. In clinical practice, experienced phys…
Maria Sousa Dias, Joanna Ashworth, Mariana Meneses, Sofia Jordão, Marco Pereira
In pediatric age groups, fever of unknown origin composes a diagnostic challenge due to its multiple possible etiologies. A high percentage of those cases is caused by infections. In this article, we describe the clinical case of an adolescent with atypical pneumonia caused by si…
Orzievna, A. F. (Abdulloeva)
… view of the need to maintain a high index of suspicion for tuberculosis (TB) in elderly patients and in patients with HIV infection, I would like to add to the reservations expressed about the guidelines for the management of adults lower respiratory tract infections.In modern c…
N. Thamilpavai, K. Prabha, Ganesan Sreeprakash
Introduction: Tuberculosis is a disease that affects mostly young individuals in their productive formative years. The risk is 20–37 times greater in HIV co- infected individuals than among those without HIV. Spinal tuberculosis is uncommon in the western world as compared to Asi…
Villar-Hernández R, Latorre I, Noguera-Julian A, Martínez-Planas A, Minguell L, et al.
Background Diagnosis of nontuberculous mycobacteria (NTM) infections remains a challenge. In this study, we describe the evaluation of an immunological NTM-interferon (IFN)-γ release assay (IGRA) that we developed using glycopeptidolipids (GPLs) as NTM-specific antigens. Methods …
Alvaro E. Galvis, Batoczki Beatrice, Iris Pecson, Craig Nakamura
Tuberculosis (TB) remains the leading cause of death from a single infectious agent. Among children, TB can have a wide range of non-specific clinical and radiological manifestations becoming a challenging diagnosis, particularly in areas with a low prevalence. We present the cas…
Vukugah TA, Ntoh VN, Akoku DA, Leonie S, Jacob A
…o meet the specific needs of children is critical to ending pediatric TB epidemic. Systematic reviews are increasingly informing policies in pediatric tuberculosis (TB) care and control. However, there is a paucity of information on pediatric TB research priorities. Methodology .…
LF Niykayo, Raman Mahajan, MJ Sagrado, YBP Ajack, B Tut Chol, et al.
Blinded point-of-care ultrasound to support tuberculosis diagnosis in
Xiaojun Wang, Cuili Yang, Meilan Zhou, Cuiping Xiao, Xiaolu Yu, et al.
**BACKGROUND:** Research on the economic burden of pediatric tuberculosis (TB) remains scarce. This study aims to investigate the hospitalization characteristics, direct medical expenses, and key determinants of hospitalization costs in pediatric TB patients. **METHODS:** We con…
Indumathi CK, Jain S, Krishnamurthy S, Alexander B
…iologically confirmed disease among children diagnosed with tuberculosis using RNTCP guidelines. Materials and methods Retrospective chart review of a cohort of 151 children (aged between 1 month and 18 years) diagnosed with Tuberculosis between December 2016 and June 2020 at a p…
Zhou H, Pei Y, Xie Q, Nie W, Liu X, et al.
… in the lower respiratory tracts of children with pulmonary tuberculosis (PTB). In this study, we assessed the value of mNGS in the pathogen diagnosis and microbiome analysis of PTB patients using bronchoalveolar lavage fluid (BALF) samples. Methods A total of 64 participants, co…
Daniel Capellán-Martín, Juan J. Gómez-Valverde, Ramon Sanchez, David Bermejo-Peláez, Lara García-Delgado, et al.
Tuberculosis (TB) is still considered a leading cause of death and a substantial threat to global child health. Both TB infection and disease are curable using antibiotics. However, most children who die of TB are never diagnosed or treated. In clinical practice, experienced phys…
Silla Varghese Thomas, Priya Rajendran, Sivakumar Shanmugam
This review provides an insight into pediatric tuberculosis (TB) diagnosis in India. Significant challenges still exist in the accurate diagnosis of pediatric TB due to the paucibacillary status of the bacilli and the nonspecific clinical symptoms. Despite advancements in newer d…
Mengyue Tong, Wenrui Ding, Hao Wu, Lijiao Yuan, Xin Ma, et al.
**BACKGROUND:** Abdominal tuberculosis (TB) in pediatric patients is a rare but serious condition that can often be misdiagnosed as malignancy or other abdominal disorders. Intestinal perforation is a rare and life-threatening complication that presents significant diagnostic and…
James Marcomic Maragia, Jepchirchir Kiplagat, Onyango Dickens, Lazarus Odeny, Stephen Olubulyera, et al.
**BACKGROUND:** Tuberculosis (TB) remains a significant global public health challenge, with 10.8 million cases and 1.23 million deaths reported in 2023. Children comprised 11% of these cases and deaths globally. In Kenya, approximately 77,000 TB cases were reporte…
Mariana Quaresma de Souza, Juliana Lemos Dal Pizzol, Ana Bárbara Scholante Silva, Felipe Furtado Gomes Riet Vargas, Denise Silva Brião, et al.
…tives: to understand the impact of the COVID-19 pandemic on tuberculosis (TB) diagnosis in different settings is essential to guide the establishment of appropriate TB control strategies. This study aimed to assess the influence of COVID-19 pandemic in laboratory diagnosis of TB …