Showing 151–175 of 200 documents
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Rittberg R, Leung B, Al-Hashami Z, Ho C
…atment, and survival data were collected through the Cancer Registry. Retrospective chart review was completed to extract past medical history and missing variables. CASPIAN/IMPower133 excluded patients with autoimmune diseases, active infection, and performance status (PS) ≥2. R…
Yao Qin, Yuanyuan Chen, Qingshan Cai
…s was a single-arm, prospective, monocentric, observational trial. From June 2020 to January 2023, 29 patients meeting the inclusion criteria were selected from Hangzhou Red Cross Hospital. These patients received a treatment regimen that included Dlm. Data were collected on pati…
Xiaorui Ruan, Kebin Chen, Ziye Li, Jianhui Wei, Ye Chen, et al.
…tions should be prioritized by antenatal care providers. **TRIAL REGISTRATION:** The study was retrospectively registered in Chinese Clinical Trial Registry Center on 06/14/2018, registration number: ChiCTR1800016635, available at: https://www.chictr.org.cn/showproj.html?proj=28…
Kartik Kumar, Saira Ghafur
…py increases the risk of treatment failure, leading to poor clinical outcomes and a significant financial burden to healthcare services. Digital health technologies may offer innovative solutions to this, but studies evaluating their utility remain sparse. To address this researc…
Christine Sekaggya-Wiltshire, Eva Agnes Laker Odongpiny, Francis Williams Ojara, Isabella Kyohairwe, Reuben Kiggundu, et al.
…tuberculosis dosing among people living with HIV (PLWH). **CLINICAL REGISTRATION:** The study is registered with Pan African Clinical Trials Registry, registration number PACTR202409710100607, registration date 07 August 2024, pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=31764.
Reza TF, Nalugwa T, Farr K, Nantale M, Oyuku D, et al.
…mance Evaluation for Linkage to Tuberculosis Care (XPEL-TB) trial uses an ultra-pragmatic, hybrid type II effectiveness-implementation design to assess the effectiveness and implementation of a streamlined strategy for delivery of Xpert testing in real-world settings. Twenty heal…
Di Tanna GL, Khaki AR, Theron G, McCarthy K, Cox H, et al.
…ted with Xpert MTB/RIF. Methods We searched PubMed, Embase, ClinicalTrials.gov, and the Pan African Clinical Trials Registry from inception to Feb 1, 2018, for randomised controlled trials (RCTs) comparing the use of Xpert MTB/RIF with sputum smear microscopy as tests for tubercu…
Fumimaro Ito, Hideki Terai, Masahiro Kondo, Ryo Takemura, Ho Namkoong, et al.
…ies could result in individualised treatment of long COVID. TRIAL REGISTRATION NUMBER: The study protocol is registered at UMIN clinical trials registry (UMIN000042299).
Hayoung Choi, Chloe Hughes, Zsofia Eke, Morven Shuttleworth, Michal Shteinberg, et al.
…HODS: Patients from the prospective European Bronchiectasis Registry (European Multicentre Bronchiectasis Audit and Research Collaboration-Bronchiectasis Research Involving Databases, Genomics and Endotyping; ClinicalTrails.gov Identifier: NCT03791086) were enrolled. Patients fro…
Nida Khan, Muhammad Ahmar Khan, Naila Muzaffar, Ahmad Ismail, Abdul Ghafoor, et al.
…S:** This is a stepped wedge, cluster randomized controlled trial with economic evaluation and health related quality of life sub-studies. Modified all-oral 9-month regimen will be sequentially rolled-out compared with the standard all-oral 11-month regimen at 12 sites in Punjab,…
Lisa M Wilson, Ian J. Saldanha, Karen A. Robinson
…f a previously published review. OBJECTIVES: To compare the clinical effectiveness of ACBT with other airway clearance therapies in CF. SEARCH METHODS: We searched the Cochrane Cystic Fibrosis Trials Register, compiled from electronic database searches and handsearching of journa…
Letícia Baltar Sobreira, Paula de Souza Silva Freitas, Luciana de Cássia Nunes Nascimento, Anne Caroline Barbosa Cerqueira Vieira, Carolina Maia Martins Sales, et al.
… for Information Sharing, Embase/Elsevier and International Clinical Trials Registry Platform, with a temporal cut-off from 2011 to 2021, sending a final synthesized sample of 18 articles, which evaluated the methodological content through the level of evidence. Results: the resu…
Charan J, Goyal JP, Reljic T, Emmanuel P, Patel A, et al.
…ention of TB in CLHIV. Methods We searched PubMed, Cochrane Clinical Trial Registry and Google Scholar from inception to December 2016. Any randomized controlled trial assessing the role of isoniazid for the prevention of TB in CLHIV was eligible for inclusion. The primary endpoi…
Ilangovan Ilavarasan, Vidhyanathan Ariharanathan, Chandrasekaran Sabitha Devi
…is were conducted, involving of about 10 Randomised Control Trials (RCTs). Studies published between 2006 and 2023 were included. Online databases such as PubMed, Google Scholar, Clinical Trial Registry India, and grey literature were searched using keywords like Isoniazid, Rifap…
Christie Akwaowo, Idongesit Umoh, Oluseyi Motilewa, Victor Umoh, Eno Usoroh, et al.
…ger multicomponent intervention study, a randomised control trial was conducted with CHWs in 18 primary health care (PHC) clusters in Nigeria. The clusters were allocated to three arms: training and cash incentive (A), training only (B), and control (C) arms. Arms (A) and (B) rec…
Katamba A, Mochizuki T, Nalugwa T, Nantale M, Oyuku D, et al.
… In this planned analysis of a pragmatic cluster-randomized trial in Uganda, we assessed whether a multicomponent strategy, including decentralized Xpert testing, decreased mortality among adults evaluated for TB. Methods Ten community health centers were randomized, using a comp…
Laura Olbrich, Bada Yang, Hayley Poore, Alia Razid, Brittney Sweetser, et al.
…racy of LC-aNAATs and LF-LAM separately in children, but in clinical practice the tests may be used concurrently, i.e. in 'parallel'. **OBJECTIVES:** To compare the diagnostic accuracy of the parallel use of LC-aNAAT on respiratory and stool specimens in children, and with LF-LA…
Christie Akwaowo, Idongesit Umoh, Oluseyi Motilewa, Victor Umoh, Eno Usoroh, et al.
…ger multicomponent intervention study, a randomised control trial was conducted with CHWs in 18 primary health care (PHC) clusters in Nigeria. The clusters were allocated to three arms: training and cash incentive (A), training only (B), and control (C) arms. Arms (A) and (B) rec…
Ggita JM, Katahoire A, Meyer AJ, Nansubuga E, Nalugwa T, et al.
…sehold contacts who participated in a randomized controlled trial evaluating home sputum collection and delivery of TB results via SMS (Pan-African Clinical Trials Registry #201509000877140). We asked about feelings, beliefs, decisions, and behaviors in response to the SMS result…
Andrew Arnott, Robert Hart, Scott McQueen, M. Watson, Malcolm Sim
…h secretion loads, although there are no randomised control trials evaluating its use. Novel vibrating mesh nebulisers generate a fine aerosol resulting in deeper lung penetration, potentially offering a more effective means of nebulisation in comparison to jet nebulisers. The pr…
Yuhan Bao, Chunxiang Wang, Haiping Xu, Yongjie Lai, Yupei Yan, et al.
…revention and control for pulmonary TB. </sec> <sec> <title>CLINICALTRIAL</title> Chinese Clinical Trial Registry ChiCTR2200055557; https://tinyurl.com/4ray3xnw </sec>
Lung T, Marks GB, Nhung NV, Anh NT, Hoa NLP, et al.
… are unclear due to the absence of evidence from randomised trials. We assessed the costs and cost-effectiveness of an active case finding strategy in Vietnam, where there is a high prevalence of tuberculosis. Methods We conducted an economic evaluation alongside the Active Case …
Ponlagrit Kumwichar, Tagoon Prappre, Virasakdi Chongsuvivatwong
… conversion rates in a 60-day cluster randomized controlled trial with patients with pulmonary tuberculosis (VOT: n=63 and DOT: n=65) with positive sputum acid-fast bacilli smears and 38 observers equally randomized into the VOT and DOT groups (19 observers per group and n=1-5 pa…
Jyoti S. Mathad, Sylvia M. LaCourse, Amita Gupta
…bservational studies or secondary analyses of TB prevention trials of women who became pregnant on study [12, 14]. The first randomized control trial of IPT in pregnancy (TB-APPRISE), demonstrates the importance of including pregnant and postpartum women in TB trials [8]. Gupta e…
Esmail A, Randall P, Oelofse S, Tomasicchio M, Pooran A, et al.
…is issue, we performed an open-label, randomized controlled trial in periurban informal settlements of Cape Town, South Africa, where we TB symptom screened 5,274 individuals using a community-based scalable mobile clinic. Some 584 individuals with HIV infection or symptoms of TB…