Showing 151–175 of 200 documents
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Harsh Patel, Preeti Singh, Abhaya Kumar
…hese steps represent a key aspect of diagnostic strategy in pediatric extrapulmonary TB.
Евгений Петрович Павленко, N. V. Rachina, S. V. Epifanova
…al Antituberculosis Center in Kursk. One of them was in the pediatric department for patients with tuberculosis of respiratory organs and the other in the 1st department for patients with multidrug-resistant tuberculosis. As pathogenetic therapy in the complex treatment of pulmon…
Korzeniewska-Koseła M
…0. In 2016, only 328 extrapulmonary TB cases were reported. Pediatric cases represented 1.6% of the total TB cases in Poland; 103 children with TB were notified. The incidence of tuberculosis has been growing along with the age group from 1.8 per 100 000 among children to 27.8 pe…
Edward SS, Akande JI, Obiajunwa PO
…esistant TB (MDR-TB). Although there are limited reports of pediatric RR/MDR-TB in Nigeria, there had not been similar report in our hospital until now. A 2-year-old girl was admitted with 2-month history of fever, cough with dyspnea, and progressive weight loss. There was no kno…
Buonsenso D, Autore G, Cusenza F, Passadore L, Bonanno F, et al.
…prompt availability in every contest because drug-resistant pediatric TB is a worldwide medical problem.
Chiang SS, Brooks MB, Jenkins HE, Rubenstein D, Seddon JA, et al.
…There were insufficient data to perform a subanalysis among pediatric secondary cases. Conclusions Household contacts of patients with drug-resistant TB should receive treatment for TB infection and disease that assumes that they, too, are infected with a drug-resistant M. tuberc…
Anneke Hesseling, M.D., Ph.D.
P1108 was a Phase I/II, open-label, single-arm, exposure-controlled dose finding study of BDQ in infants, children, and adolescents living with and without HIV, with clinically diagnosed or bacteriologically confirmed rifampin-resistant tuberculosis (RR-TB). The study was designe…
Gavin Churchyard, MBBCh MMed FRCP FCP(SA) PhD, Amita Gupta, MD, MHS, Anneke Hesseling, MD, PhD, Susan Swindells, MBBS
The purpose of this study is to compare the efficacy and safety of 26 weeks of delamanid (DLM) versus 26 weeks of isoniazid (INH) for preventing confirmed or probable active tuberculosis (TB) during 96 weeks of follow-up among high-risk household contacts (HHCs) of adults with mu…
Deniz Aygün, Tarık Yıldırım, Özlem Başoğlu Öner, Sezer Toprak, Aylin Babalık, et al.
Objective: Resistance to at least isoniazid and rifampicin, which are the most important drugs in TB treatment, is called multidrug-resistant tuberculosis (MDR-TB). MDR-TB is a life-threatening condition that affects children as well as adults. Material and Methods: The medical r…
Deniz Aygün, Tarık Yıldırım, Özlem Başoğlu Öner, Sezer Toprak, Aylin Babalık, et al.
Objective: Resistance to at least isoniazid and rifampicin, which are the most important drugs in TB treatment, is called multidrug-resistant tuberculosis (MDR-TB). MDR-TB is a life-threatening condition that affects children as well as adults. Material and Methods: The medical r…
Nisha Kumari, Anuj Khatri
TB remains a leading cause of morbidity and mortality in developing countries. The incidence of congenital TB is underestimated. Current recommendations regarding the management of neonates of mothers with tuberculosis are variable and no tangible guidelines have been advised. Co…
Gita Naidu, Alane Izu, Richard Madimabe, R Wainwright, Stelios Poyiadjis, et al.
Abstract Background Children with cancer are immunocompromised, with increased susceptibility to infections including infections with Mycobacterium tuberculosis. Method This prospective study, enrolled children one-19 years old hospitalized for cancer treatment. Screening for M. …
Aarti Rahangdale
Bone tuberculosis (TB) is relatively uncommon form of extrapulmonary TB in children. It is estimated that 1-6 % children with primary infection may develop bone and joint TB in 1-3 years if left untreated. Though short course chemotherapy has been found to be effective in treatin…
Shagun Walia, Varinder Singh
This case report is about a 13 years old boy who was diagnosed to have sputum negative pulmonary tuberculosis. Anti-tuberculosis treatment (ATT) was continued for it and he initially showed improvement but later transitioned into a slowly progressive persistent pneumonia. In this…
Kyi-Phyu Aye, Sabai Phyu, Thet-Su Mon, Thwe-Zin Soe
Abstract Background Human immunodeficiency virus/ acquired immune deficiency syndrome (HIV/AIDS) constitutes a major global public health concern. There are an estimated 237,000 people living with HIV in Myanmar with prevalence of 0.57%, the fourth highest in South East Asia regi…
Courtney M. Yuen, Moorine Sekadde, Brian Kaiser, Brenda Waning, Stephen M. Graham
Tuberculosis (TB) is a major cause of morbidity and mortality in children and adolescents globally.1 While children generally experience better treatment outcomes with less drug-related toxicity than adults when treated for TB disease or infection, the length of common treatment …
И. С. Долгополов, O. B. Federiakina, O. M. Volzhenina, G. G. Erokhina, K. A. Leonov, et al.
…tes, as well as the lack of alertness of neonatologists and pediatricians. Less than 500 confirmed cases of congenital tuberculosis have been described in the available literature. Mortality ranges from 15 to 33%. Early diagnosis and adequate therapy are essential to improve the …
Preeti Sharma, Alok Raina, Kavita Sharma
Background: Nikshay Poshan Yojana (NPY) was launched in 2018 aiming to provide nutritional incentive of INR 500 per month to all tuberculosis (TB) patients till they complete their treatment. Aim of present study is to determine the number (proportion) of patients being treated f…
Anna Daunt, Alastair McGregor, Cassandra Watson, Denis Keane, Ashley Whittington, et al.
Abstract Background Central nervous system tuberculosis (CNS TB) has high mortality and morbidity and can be further complicated by paradoxical reactions. There is increasing use of infliximab for steroid-resistant inflammation in CNS TB. We reviewed data from patients with CNS T…
Hassaan Ali Ahmad
Abstract Background Bedaquiline, approved in 2012 in the United States as the first new drug for multidrug-resistant tuberculosis in over 40 years, showed increased mortality in clinical trials compared to placebo in addition to other side effects. We analyzed real-world side eff…
Marais BJ
Children suffer a huge and often an unrecognized burden of tuberculosis (TB) in endemic countries like India. Better data have improved the visibility of childhood TB, but the establishment of functional TB prevention and treatment programs for children remains challenging. Barri…
Nirupam Nadella, Prince Saha, Rajeev Bahadursha, Korvi Nitish Kumar, Madhur Anand
A BSTRACT Extrapulmonary tuberculosis (EPTB) is the clinical entity that is gaining more recognition. Still, it may emerge in various ways, making it difficult to diagnose. Even though pulmonary tuberculosis is the most common variety, EPTB may affect many organ systems and often…
Yatin Dholakia
Tuberculosis (TB), along with drug-resistant tuberculosis (DRTB), continues to be a major global public health risk threatening to reverse the efforts to end TB by 2035.[1] An estimated 10.8 million cases were identified in 2023, and 400,000 multidrug-resistant tuberculosis (MDR-…
Mohamad Zacky Amirullah, Sudarto Sudarto, Zen Ahmad, Bryan Arista Hartono
Rifampicin-resistant tuberculosis remains a major global health challenge, particularly when occurring as primary resistance in patients without prior tuberculosis treatment. Tuberculosis drug resistance incidence in Indonesia expected 2.2% primary and 25% with prior anti-tubercu…
Ravi C, Dabadghao P
Treatment of multi-drug resistant (MDR) tuberculosis (TB) includes aminoglycosides and ethionamide. A 16-year-old girl presented with sudden onset of paralysis, dyselectrolytemia mimicking Gitelman syndrome, and ethionamide-induced hypothyroidism. Monitoring electrolytes during M…