Showing 126–150 of 200 documents
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Salindri AD, Kipiani M, Lomtadze N, Tukvadze N, Avaliani Z, et al.
…e relationship between common comorbidities in persons with tuberculosis (TB) (including human immunodeficiency virus [HIV], diabetes, and hepatitis C virus [HCV]) and post-TB mortality. We conducted a retrospective cohort study among persons who initiated treatment for rifampici…
Kuchukhidze G, Baliashvili D, Adamashvili N, Kasradze A, Kempker RR, et al.
…mong patients with multidrug and extensively drug-resistant tuberculosis (M/XDR TB). We aimed to identify long-term clinical outcomes of patients who were LFU during second-line TB treatment. Methods We conducted a follow-up study among adults who received second-line TB treatmen…
Maïssala Zoutené, Akouvi Mawussé Edjodjinam Ako, Koffi Atsu Aziagbe, Narcisse Viani Gateu Tadjom, Tété Amento Stéphane Adambounou, et al.
…IVES:** The increasing burden of extensively drug-resistant tuberculosis (XDR-TB) undermines global TB control efforts. **METHODS:** This was a case series study conducted from January 1, 2007, to December 31, 2024, in the Department of Pulmonology at Sylvanus Olympio University…
Matúš Dohál, Olha Konstantynovska, Michaela Hromádková, Marek Štrba, Karolína Doležalová, et al.
…d migration into Central Europe, raising concerns regarding tuberculosis (TB) spread. **METHODS:** We conducted a molecular-epidemiological study including all Ukrainian migrants with culture-confirmed TB in Slovakia and the Czech Republic between September 2021 and December 202…
Francesca Saluzzo, Andrea Maurizio Cabibbe, Richard Anthony, Alexandra Aubry, Francis Drobniewski, et al.
…rted poor treatment outcomes for extensively drug-resistant tuberculosis (TB) in the European region highlight the urgent need for effective and context-appropriate diagnostic strategies. While the World Health Organisation (WHO) provides model algorithms, these require adaptatio…
Prasitpuriprecha C, Jantama SS, Preeprem T, Pitakaso R, Srichok T, et al.
…rm for determining if a patient is positive or negative for tuberculosis and classifying several types of drug resistance. The constructed model is evaluated and compared to current methods described in the literature. The proposed model was assessed using two datasets of chest X…
Zhao LL, Huang MX, Xiao TY, Liu HC, Li MC, et al.
…valence, risk and genetic characteristics of drug-resistant tuberculosis (TB) from a tertiary care TB hospital in China. Patients and methods We carried out a retrospective study including isolates from 189 patients with pulmonary TB at Fuzhou Pulmonary Hospital. All isolates fro…
Desai U, Joshi JM
Background Drug-resistant tuberculosis (DR-TB) is a global problem with only 52% reported cure rate. Extrapulmonary (EP) DR-TB poses a formidable diagnostic, therapeutic challenge. We aimed to study their clinical profile and treatment outcomes under the programmatic setting. Mat…
Zubeida Salaam-Dreyer, Elizabeth M. Streicher, Frederick A. Sirgel, Fabrizio Menardo, Sònia Borrell, et al.
Abstract Rifampicin mono-resistant TB (RMR-TB) constitutes 38% of all rifampicin-resistant TB (RR-TB) in South Africa and is increasing. We aimed to compare RMR-TB with multidrug-resistant TB (MDR-TB) within a high TB, RR-TB and HIV burden setting. Patient-level clinical data and…
Zumla, Alimuddin, Wallis, Robert, Klein, Nigel, Oleson, Ole, Lang, Hannu, et al.
Xiaowei Dai, Chung‐Yi Li, N H Wang, S S Chen, Li Tian, et al.
The prevalence of fluoroquinolones (LFX and MFX) resistance in rifampicin-resistant MTB is very serious. LFX and MFX show incomplete bidirectional cross-resistance. BDQ and LZD have the most promising future in the treatment of MDR-TB. Improve drug-resistance testing will help to…
H J Chen, Xubin Zheng, Y Wang, Jinze Li, Biao Xu
Number of patients under drug resistance surveillance and the detection of MDR/XDR-TB trended to increase in Guizhou province from 2012 to 2019. The detection rate of MDR/XDR-TB in high-risk groups was higher than low-risk groups.
Pavithra GB, R. Prassanna Adithiyan, B Charumathi, Timsi Jain
Background: Non- adherence is one of the major risk factors for the emergence of MDR and XDR TB. It is also one of the key factors responsible for treatment failure, disease relapse, prolonged infection and death. This study was conducted to explore the various factors contributi…
World Health Organization. Regional Office for the Eastern Mediterranean
World Health Organization
Keikha M, Majidzadeh M
We found that the frequency of Beijing genotype among XDR-TB strains was high. The data in this study would help guide the TB control program, and we however need further investigation to confirm the reliability of the present findings.
Elwira Sieniawska
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Despite the successes in the development of diagnosis and treatment of this disease, it still poses a significant threat to humanity, especially in countries with an average and low level of healthcare de…
Hamidah Hussain, Amyn A. Malik
Preventing tuberculosis infection from progressing to tuberculosis disease is a crucial component of the goal to eliminate tuberculosis. When deciding on the use of tuberculosis preventive therapy among household contacts, policy makers regularly ask questions, such as whether tu…
Christoph Lange, Anca Vasiliù, Anna M. Mandalakas
Tuberculosis is the leading cause of death attributed to a single infectious pathogen worldwide. Despite the availability of anti-tuberculosis therapies for more than half a century, the number of people affected by tuberculosis reached a historical peak in 2021.1WHOGlobal tuberc…
Yue Wang, Weibing Wang
Given that existing tuberculosis interventions and strategies are not going to enable achievement of WHO's goal to eliminate tuberculosis by 2050,1Xu K Ding C Mangan CJ et al.Tuberculosis in China: A longitudinal predictive model of the general population and recommendations for …
Beijing Hospital
Background: Drug resistant tuberculosis is a serious public health problem that threatens the health of human life and the development of society and economy. At present, the diagnosis of drug-resistant tuberculosis mainly depends on traditional drug susceptibility test. But it …
Michael Reid, Eric Goosby, Sebastian Kevany
…r High-Level Meeting of all UN member states made defeating tuberculosis a global political priority.1Stop TB PartnershipUN high-level meeting on TB–key targets and commitments.http://www.stoptb.org/global/advocacy/unhlm_targets.aspDate: 2018Date accessed: December 12, 2018Google…
Pradeep M Muragundi
Introduction: Extensively Drug-Resistant Tuberculosis (XDR-TB) is a recent challenge for tuberculosis control program. The absence of the functional drugs and high rate of the failure in treatment and mortality rate also high jeopardize for epidemiology. Its prevalence is unknown…
Gunar Günther, Lorenzo Guglielmetti, Claude Leu, Christoph Lange, Frank van Leth, et al.
…ckground Access to comprehensive diagnostics and novel anti-tuberculosis medicines is crucial to improve tuberculosis control at times of emerging Mycobacterium tuberculosis drug resistance. Methods We investigated access to genotypic and phenotypic M tuberculosis drug susceptibi…
Victor Næstholt Dahl, Simon Tiberi, Delia Goletti, Christian Wejse
… countries healthcare systems will be strained. Even though tuberculosis (TB) incidence rates had been gradually decreasing over the years in Ukraine and Russia with rates of 73 and 46 per 100,000 individuals in 2020 (WHO 2021WHOGlobal tuberculosis report 2021. World Health Organ…