Showing 126–150 of 200 documents
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Brilliant Deva Aspada, Komang Agung Irianto Suryaningrat, Pudji Lestari, Primadenny Ariesa Airlangga
Spinal Tuberculosis is a secondary tuberculosis due to hematogenous spread from the primary infection site (lungs) caused by the bacteria Mycobacterium tuberculosis and is chronic-destructive in nature which attacks the spine. Manifestations in the form of deformity can also be c…
Ngadaya E, Kimaro G, Sandi E, Mnyambwa NP, Wilfred A, et al.
Background Diagnosis of pulmonary tuberculosis remains grim, especially in resource-limited settings. Low quality of sputum, particularly among seriously ill, HIV/AIDS, and pediatric patients might result in missing the diagnosis. This study evaluated the performance of GeneXpert…
Nicol MP, Wood RC, Workman L, Prins M, Whitman C, et al.
Microbiological diagnosis of pediatric pulmonary tuberculosis (TB) is challenging due to the difficulty of collecting and testing sputum from children. We investigated whether easily-obtained oral swab samples are useful alternatives or supplements to sputum. Oral swabs and induc…
Khondker Qamruzzaman, Syed Ahsan Tauhid, Dr. Md. Ashiqur Rahman, Sk Sadek Ali, Dr. Md. Nahidul Islam, et al.
Background: Pulmonary tuberculosis (PTB) remains a significant health issue in children. Early and accurate diagnosis is critical but challenging, The GeneXpert test, a rapid and accurate molecular diagnostic tool, has improved TB detection by identifying Mycobacterium tuberculos…
Made Winatra Satya Putra, Made Agus Maharjana, I Ketut Siki Kawiyana
Background: Tuberculosis of the bone is a serious problem in developing countries, extra-pulmonary tuberculosis is more common among children. The characteristics of tuberculosis osteomyelitis in children are different. Therefore, the disease is often neglected or diagnosis is de…
Claudia Ozela El- Husny, Ângela Maria Rodrigues Ferreira, Jamilie Suelen dos Prazeres Campos, Kamila Nancy Gonçalves da Gama, Iací Proença Palmeira, et al.
Introduction: Tuberculosis control tools are a challenge to primary health care, due to the delay of people from the appearance of the first symptoms to the search for the first health-care service, and health-care services leading to difficulties and delay in establishing the di…
Deepmala Pandey, Ankur Yadav
Background: Body fluids are commonly used for diagnosis as sputum is not reliable in children. Hence it is essential to study efficacy of body fluids in comparison to GeneXpert which is a new diagnostic modality. Objectives of this study was to incidence of rifampicin resistance,…
Muhammad Ali Shodikin, Desie Dwi Wisudanti, Annisa Nadhifa Witanto
Background: Tuberculosis (TB) remains a major public health problem globally. TB in children is an important component in TB control. The diagnosis of TB in children until now is still challenging, underdiagnosis often occurs in primary health facilities in Indonesia. This study …
Singhal R, Dayal R, Bhatnagar S, Nayak M, Yadav N, et al.
…d as compared to CBNAAT in gastric aspirate (GA) samples in pediatric tuberculosis (TB). Methods This cross-sectional study was performed at Department of Pediatrics of a tertiary care hospital. Children aged 0-18 y diagnosed as presumptive tuberculosis were consecutively enrolle…
Xiaoxia Wang, Shaomei Huang, Hua Chen
… clinical and Imaging characteristics between children with pediatric pulmonary tuberculosis (PTB) and children with pneumonia who were initially suspected of PTB, and to explore valuable indicators for differential diagnosis. Methods This retrospective study enrolled pediatric i…
Farina E, D'Amore C, Lancella L, Boccuzzi E, Ciofi Degli Atti ML, et al.
Background Intercepting earlier suspected TB (Tuberculosis) cases clinically is necessary to reduce TB incidence, so we described signs and symptoms of retrospective cases of pulmonary TB and tried to evaluate which could be early warning signs. Methods We conducted a retrospecti…
Maphalle LNF, Michniak-Kohn BB, Ogunrombi MO, Adeleke OA
Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill health and death in children as well as adolescents universally. Minors are particularly susceptible to this severe illness t…
Joana Vieira, Andreia Fiúza Ribeiro, Paula Correia, Helena Loureiro
Background: Tuberculosis disease under six years is an indicator of recent transmission within the community. We aim to characterize tuberculosis disease in children under six years in a pediatric department of a level II hospital in the Lisbon metropolitan area, which serves a h…
Raizada N, McDowell A, Parija D, Sachdeva KS, Khaparde SD, et al.
Background A significant proportion of pediatric tuberculosis (TB) patients go unnotified due to the challenges in diagnosis of TB among children. The experiences of this vulnerable group while going through the TB care cascade remain largely undocumented. The aim of this study w…
Caroline Lacroix, Philippe Martin, Sebastien Turcotte, Steven DeRoche, Vanessa Magluilo, et al.
…TION: Despite being more prevalent in developing countries, tuberculosis (TB) remains an important health problem in Canada. Long diagnosis delays of respiratory tuberculosis are associated with adverse consequences for the patient but also for the community. From a public health…
Bárbara Maitee Carmenates-Álvarez, Ana Dianelis Reyes-Escobar, Yosvany Rojas-Peláez, Yamilka Joamis Peña-Borroto, Yon Luis Trujillo-Pérez
Background: tuberculosis is a public health problem to a world scale. It is a systemic illness that can rarely affect the gastrointestinal tract and it is not very frequent in pediatrics. Its diagnosis constitutes a great challenge. Objective: to present the case of an adolescent…
Saldaña N, Parra M, La Garza E, Trujillo D, Ayala S, et al.
…to WHO data, in 2016 10.4 million people were infected with tuberculosis (TB), from which one million were patients ≤18 years, and 250,000 deaths. The diagnosis of TB in pediatric patients is a challenge given the clinical behavior. Methods This is a retrospective, descriptive, a…
Halisyah Hasyim Lubis
Introduction: Drug-resistant tuberculosis (DR TB) is a condition where Mycobacterium tuberculosis is resistant to isoniazid, rifampicin or resistant to isoniazid and rifampin as well as other first-line anti-tuberculosis drugs (OAT). Tuberculosis (TB) is a contagious infectious d…
Venkatesh Karthik S., Jigisha Patadiya
Background: The diagnosis of tuberculosis (TB) by microbiological tests is a major challenge particularly in children. The use of Xpert analysis, a rapid genetic testing modality is not widely reported in our locality. The aim of the study to evaluate the diagnostic accuracy of G…
Ayesha Tariq, Muhammad Naeem
Background: The prevalence of rifampicin resistance in pediatric patients with Mycobacterium tuberculosis is a growing concern, particularly in regions with high TB burden. Early and accurate detection of drug resistance is crucial for effective treatment and management, especial…
Putu Ardy Hartadi, Putu Siska Suryaningsih
Tuberculosis (TB) in children is often difficult to diagnose due to nonspecific symptoms and limited microbiological testing. Severe anemia in children is usually evaluated for nutritional deficiencies or hematological disorders, but can also be an indicator of chronic infections…
Khurana AK, Dhingra B
Tuberculosis continues to haunt mankind since its discovery more than a century ago. Although commendable advancements have been made in the diagnosis as well as treatment, especially in the last couple of decades, the healthcare burden of this disease worldwide is immense. Conti…
Santos ACEZ, Sztajnbok J, Duarte-Neto AN, Sousa AFT, Lopes AGD, et al.
Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to dis…
Kin-Sun Wong, Yen-Chun Huang, Han-Chung Hu, Yhu-Chering Huang, Chang-Hui Wen, et al.
…he tuberculin skin test (TST) in Taiwanese children for the diagnosis of active tuberculosis (TB). **METHODS:** A retrospective chart analysis of pediatric patients (<18 years of age) who underwent QFG-IT tests and TST for the confirmation of active TB between January 2008 and J…
Fan Lü, Bochao Guan, Michael Cheng, Liu C, Y Tian, et al.
…st; Chang Liu,3 Yao Tian,1 Ran Li,1 Yu Chen1 1Department of Tuberculosis, Shenyang Tenth People’s Hospital, Shenyang Chest Hospital, Shenyang, Liaoning Province, 110044, People’s Republic of China; 2Geriatric Cardiology Department of the Second Medical Center & National Clinical …