Showing 126–150 of 157 documents
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Devesh Bhargude, Anjali M. Rajadhyaksha, Meghna Vaidya
India has the highest estimated burden of tuberculosis infection (TBI) globally caused by Mycobacterium Tuberculosis , with nearly 35-40 crores Indian population having TBI, of which 26 lakhs people (18-36 lakh) are estimated to develop Tuberculosis (TB) disease annually. An inte…
Hutsaya Tantipong, Yupares Payaprom
The low detection rate of multidrug-resistant tuberculosis (MDR-TB) is one of the major obstacles to TB control in Thailand. Thus, this study aimed to assess pre-diagnosis and pre-treatment attrition rates among patients suspected of having MDR-TB, identify factors related to pre…
Kizito Omona, Christopher Ogwang
: Multidrug-resistant tuberculosis (MDR-TB) is a major public health hazard on a global scale. It is a kind of tuberculosis (TB) infection produced by bacteria resistant to at least two of the most effective first-line anti-tuberculosis (anti-TB) drugs: isoniazid and rifampicin. …
Naveed Pervez, Zia Ul Haq, Imtiaz Khan, Muhammad Umar
… the frequency of successful outcome of multidrug-resistant tuberculosis treated as outpatient in a tertiary care center. Subject and methods: This was a descriptive cross-sectional study done from 13 April, 2018 to 13 Oct, 2018. All the patients fulfilling inclusion criteria hav…
Ravi C, Dabadghao P
Treatment of multi-drug resistant (MDR) tuberculosis (TB) includes aminoglycosides and ethionamide. A 16-year-old girl presented with sudden onset of paralysis, dyselectrolytemia mimicking Gitelman syndrome, and ethionamide-induced hypothyroidism. Monitoring electrolytes during M…
Chunawala Z, Shah I
Aim To study clinical profile of children with mediastinal tuberculosis (TB). Methods This retrospective study was undertaken between January 2015 and March 2018 in children diagnosed with mediastinal TB. Clinical history, examination and radioimaging, such as chest X-ray and HRC…
R Kamara, JE Carlos, Foday Sahr, Lynda Foray, MJ Saunders, et al.
<h3>Background</h3> Drug-resistant tuberculosis (DR-TB) is a global public health emergency. In April 2017, the National Tuberculosis Programme (NTP) of Sierra Leone, a high TB burden country, began using WHO-approved second-line drugs in short and long DR-TB treatment regimens. …
Winnie Nakiboneka
Background: Tuberculosis (TB) remains one of the world's leading causes of adult morbidity and mortality resulting in an estimated 8.8 million incident cases and 1.4 million deaths Up to 92% of the TB cases occur in low and middle-income countries with the sub-Saharan Africa regi…
Sherchan JB, Dongol A, Humagain S, Joshi A, Rana Magar S, et al.
…es had multidrug resistant isolates and only 18 (36.73%) of pediatric age group patients had multidrug resistant isolates (p-value<0.05) Conclusion: Drug-resistant bacteria were observed in urine samples. Effective treatment and prevention of urinary tract infection need detailed…
Bhanudeep Singanamalla, Lokesh Saini, Priyanka Madaan, Paramjeet Singh, Pankaj C. Vaidya, et al.
A 12-year-old girl with multidrug-resistant pulmonary tuberculosis presented with a 5-day history of headache and psychosis; at the time, she was taking a complex antitubercular therapy (ATT; kanamycin, levofloxacin, ethionamide, pyrazinamide, cycloserine, ethambutol) and pyridox…
Jyoti S. Mathad, Sylvia M. LaCourse, Amita Gupta
To end the tuberculosis (TB) epidemic, the World Health Organization (WHO) recommends improving access to testing and treatment of latent TB infection (LTBI) [1]. Despite recent epidemiologic studies demonstrating an approximately twofold increased risk of active TB in peripartum…
Ifeanyi Nwafor, Chinyelu Uchenna Ufoaroh, Basil C. Ezeanolue, Evaristus Afiadigwe, G Obasikene, et al.
Background: Tuberculosis (TB) is a contagious and potentially fatal infectious disease with significant global morbidity and mortality. Boththe disease and some anti-TB medications have been linked to hearing loss. The study objective is to determine the Types and severity of hea…
О. М. Raznatovska, M. O. Shalmina, А. В. Федорец, О.S. Shalmin, М. С. Потапенко
…rs with the peculiarities of pulmonary multi-drug resistant tuberculosis (MDRT) in a patient with idiopathic pulmonary fibrosis (IPF) resulted from a long exposure to environmental factors at the workplace.Materials and methods. The article deals with a clinical case of own obser…
Abebaw Y, Abebe M, Tola HH, Mehammed Z, Getahun M, et al.
…Data on the burden of bacteriologically confirmed childhood Tuberculosis (PTB) and drug-resistant TB in Ethiopia is limited due to difficulties related to its diagnosis in this population. Therefore, this study aimed to assess bacteriologically confirmed childhood PTB Case Notifi…
Mane SS, Janardhanan J, Pustake M, Ali MK, Khan GI
Introduction Central Nervous System tuberculosis (CNS-TB) is the most lethal form of extra-pulmonary TB, especially in children. In this study, we have discussed patterns of drug resistance in pediatric CNS-TB. Materials and methods Prospective observational study conducted on 10…
J Wallenfels, M Malý
…f HIV-positive persons in the Czech Republic diagnosed with tuberculosis (TB) in 2000-2020. MATERIAL AND METHODS: Data sources were mainly the national online TB register (RTBC), which is part of the information system of the Public Health Service, and the national electronic reg…
Abdul Massiah Metry, Issa Al Salmi, Seif Al-Abri, Faisal Al Ismaili, Yaqoub Al Mahrouqi, et al.
…States Renal Data System showed 1.2% and 1.6% incidences of tuberculosis (TB) in patients on peritoneal dialysis and hemodialysis (HD), respectively. Kidney transplant (KTX) patients have higher rates. We studied the epidemiology and outcome of TB in patients with kidney dysfunct…
Emmanuel Tachiwenyika
…acilities offered TB testing, 5 had TB guidelines and 5 had pediatric TB job aides. Five out of 7 microscopes and 4/7 GeneXpert machines were functional. About 64.1% of HCWs had childhood TB training, 51% had ever received mentorship on childhood TB management, 53.1% had ever col…
Jorge Roberto Mosqueira Sanchez, M. Moreno, Julio Cesar Layseca Ortiz, Nancy Victoria Mogrovejo Olivera, Alvaro Oyarce Calderón, et al.
Background. Tuberculosis is a public health problem considered to be the world's leading cause of death from an infectious disease among adults. Diagnosis is often challenging and is based on clinical, epidemiological, radiological, bacteriological, histological and biochemical f…
Nana Kiria, Zaza Avaliani, Mamuka Chincharauli, Lali Mikiashvili
…gia. <b>Method:</b> NTP has provided universal access to TB diagnosis and treatment countrywide; introduced WHO-approved modern diagnostic methods; FAST strategy was successfully implemented for early TB-detection in general healthcare facilities; NTP participate in the pilot pro…
Shimaa Anwer Emam
Tuberculosis (TB) is a disease of great antiquity and has almost certainly caused more suffering and death than any other infection. A total of 40 patients were registered with a diagnosis of MDR-TB during 2010–2018 in Minia. The majority of patients were from rural areas (27; 67…
Jennifer Ann Mendoza‐Wi
The Philippines has a high burden of tuberculosis (TB) with around 1 million active cases. In 2019, prior to the coronavirus disease 2019 (COVID-19) pandemic, the Philippines ranked fourth in terms of TB cases, with 554 TB cases per 100,000 population. TB is the second leading ca…
Gareth Dobson, Craig H. Robson, John E. Williams, Nitin Mukerji
… Her medical history included multidrug resistant pulmonary tuberculosis (TB) diagnosed around five years earlier. She underwent successful treatment for this in the form of a two year course of pyrazinamide, moxifloxacin, linezolid, and azithromycin. She had no history of immuno…
Gavin Churchyard, MBBCh MMed FRCP FCP(SA) PhD, Amita Gupta, MD, MHS, Anneke Hesseling, MD, PhD, Susan Swindells, MBBS
…isoniazid (INH) for preventing confirmed or probable active tuberculosis (TB) during 96 weeks of follow-up among high-risk household contacts (HHCs) of adults with multidrug-resistant tuberculosis (MDR-TB) (index cases). High-risk HHCs are those with HIV or non-HIV immunosuppress…
Seddon JA, Johnson S, Palmer M, van der Zalm MM, Lopez-Varela E, et al.
…estimated 30,000 children develop multidrug-resistant (MDR) tuberculosis (TB) each year, with only a small proportion diagnosed and treated. This field has historically been neglected due to the perception that children with MDR-TB are challenging to diagnose and treat. Diagnosti…