Showing 126–150 of 200 documents
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Carnazzo S, Cerruto C, Comisi FF
… a significant global health challenge, particularly within pediatric populations. This article reports the case of a 7-year-old female patient admitted with massive fibrinous pleural effusion secondary to TB, highlighting the key role of ultrasound in disease monitoring and ther…
A J Cabrera Goncalves, B C Adkinson, D Ashkin
Abstract Introduction Interventional bronchoscopy in pediatrics is challenging due to small airway caliber, limited pulmonary reserve, and scarce appropriately sized instrumentation. Expertise is often concentrated in high-volume centers, making complex airway interventions diffi…
Jun Komukai, Kaori Yamamoto, Osamu Tokunaga, Hiharu Inoue, Takayuki Wada
This study examined pediatric tuberculosis (TB) cases in Osaka City from 2008-2023, focusing on diagnostic methods and molecular epidemiology using variable number of tandem repeats (VNTR) analysis and whole-genome sequencing (WGS). Among 29 children aged 0-14 years (notification…
Herdea A, Marie H, Negrila IA, Abdel Hamid Ahmed AD, Ulici A
Background Pediatric osteoarticular tuberculosis (TB) remains a significant global health challenge, particularly in resource-limited settings, where delayed diagnosis and treatment frequently lead to severe long-term complications. Despite advancements in TB control, skeletal TB…
Christine Anterasian, Kim Dill-McFarland, Josh Ivie, Humphrey Mulenga, Justin Shenje, et al.
…host genetic variation is associated with susceptibility to pediatric tuberculosis disease and blood biomarker expression. Methods We used a case-control study with a 12–36-mo prospective observation period to examine susceptibility to tuberculosis in children aged 2 mo to 5 yr w…
Zhao A, Butala N, Luc CM, Feinn R, Murray TS
Pediatric patients with untreated tuberculosis infection (TBI), also called latent TBI, are at risk of progression to active TB disease. The primary aim of this study was to identify factors associated with higher rates of missed appointments and failure to complete therapy for p…
Deswita Deswita, Arif Rohman Mansur, Mutia Farlina
…ublic health concern, particularly in developing countries. Pediatric TB poses a unique challenge due to the difficulty in diagnosing the disease in young children. Early detection and treatment of TB are crucial to prevent transmission and improve outcomes. Parent involvement in…
Matúš Dohál, Peter Kunč, Jaroslav Fábry, Igor Porvazník, Ivan Solovič, et al.
…ulous mycobacteria (NTM) are rare but emerging pathogens in pediatric populations, particularly in countries where BCG vaccination has been discontinued. Their diagnosis is often delayed due to nonspecific symptoms and limited microbiological sensitivity. **METHODS:** We conduct…
Kamble B, Malhotra S
…a, all ages have assumed importance including the burden of pediatric TB. The current study was carried out to study the profile of pediatric TB patients and factors associated with treatment outcome of these patients registered in Faridabad district of Haryana, India. Methods Th…
Betül Okuyan, Fatih Tok, Sevgi Karakuş, KAYMAKÇIOĞLU, BEDİA, Mesut Sancar
…soniazid (INH), rifampicin (RIF), and pyrazinamide (PZA) in pediatric tuberculosis patients. The study was carried out in 3 different training-research hospitals in Istanbul, Türkiye between 2011 and 2012. The pediatric patients (aged ≤14 years) who initiated the standard primary…
Aole Li, Yuhang Wu, Xinxin Zeng, Xi Zhang, Jiong Li, et al.
**OBJECTIVE:** Pediatric tuberculosis (TB) remains an important part of the global TB burden; however progress in this population has been slower and less consistent than that in adults. The influence of recent epidemiological shifts, including those following the COVID-19 pandem…
Vega Pangaribuan, Muhammad Arifin Parenrengi, Wihasto Suryaningtyas
…e literature on the clinical presentation and management of pediatric cervical spine tuberculosis (CST) and evaluate the outcomes of conservative or surgical treatment based on anatomical location (craniovertebral junction [CVJ], subaxial, and cervicothoracic junction). **METHOD…
Mejia- Mertel J, Rojas -Hernandez J
…nical manifestations in HTLV-1, still studies are needed in pediatric population to improve diagnosis and treatment of infected patients. Methods Descriptive, retrospective cohort study, conducted in our referral pediatric hospital in Cali, Colombia. Included pediatric patients (…
Dong-Hyun Lee, Young‐Jin Choi, Jieun Kim, Eunhee Han, Mi Hyun Bae
…bution of bacterial species in NPS specimens collected from pediatric and adult patients by employing RT-PCR (Allplex respiratory panel 4, RP4, Seegene) to estimate its applicability in a panel-based assay for detecting respiratory viruses. Methods: We used 271 and 173 NPS specim…
Kumar NP, Hissar S, Thiruvengadam K, Banurekha VV, Suresh N, et al.
Pediatric TB poses challenge in diagnosis due to the paucibacillary nature of the disease. We conducted a prospective diagnostic study to identify immune biomarkers of pediatric TB and controls (discovery cohort) and obtained a separate "validation" cohort of confirmed cases of p…
Jayagandan S, Singh J, Mudliar SR, Shankar P, Maurya AK, et al.
…ective Microbiological confirmation of tuberculosis (TB) in pediatric cases is challenging due to its paucibacillary nature and difficulty in specimen collection. This study aimed to validate stool as an alternative sample for the diagnosis of pediatric pulmonary TB via Xpert MTB…
Lina Souan, Rawad Rihani, Maher A. Sughayer
…nfection can lead to significant morbidity and mortality in pediatric hematopoietic stem cell transplant recipients. Early detection of CMV infection is crucial for managing its impact. Aim: (QFM) tests in predicting CMV infection and graft-versus-host disease (GvHD) in pediatric…
Nissa Prima Sari Nissa Prima
…s (SES), healthcare support, and medication adherence among pediatric TB patients in Solok, West Sumatera, Indonesia. </p> <p style="font-weight: 400;"><strong>Methods:</strong> A cross-sectional study was conducted involving 57 pediatric TB patients. Data…
Olivia F. Hunter, Furaha Kyesi, Amrit Ahluwalia, Zeinabou Niamé Daffé, Patricia Munseri, et al.
…in whom diagnostic confirmation is challenging. We assessed pediatric IPT implementation and adherence at a pediatric HIV clinic in Tanzania. Methods: Eligible HIV-infected children aged 1-15 years receiving care at the DarDar Pediatric Program in Dar es Salaam who screened negat…
Qian M, Li F, Zhang Y, Qiao Z, Shi Y, et al.
Diagnosis of pediatric paragonimiasis is difficult because of its non-specific clinical manifestations. We retrospectively reviewed the records of pediatric paragonimiasis in Children's Hospital of Fudan University from January 2011 to May 2019. The confirmed diagnosis of paragon…
Luciana Cotignola, Aixa Reusmann, Martín Rubio, Enrique Paz, Víctor Ayarzabal, et al.
…ulosis (ATB) is a rare presentation of tuberculosis (TB) in pediatric patients, and its diagnosis can be challenging. This study aimed to analyze the role of surgery in patients with ATB presenting with acute abdomen. We conducted a retrospective analysis of pediatric patients un…
Awewura Kwara, MD
Lack of quality-assured pediatric formulations of the first-line antituberculosis (anti-TB) drugs is barrier to optimized tuberculosis (TB) treatment outcome in children. In 2010 and subsequently modified in 2014, the World Health Organization (WHO) recommended increased dosages …
Robert Dennis Garcia
…gic diagnoses of clinically- and radiographically-confirmed pediatric pneumonia cases admitted in a private hospital. Secondarily, a discussion of specific etiologies is made. Methodology: Each consecutive, inpatient, pneumonia referral/admission in either one of two private, urb…
Jinyu Chen, Zhengxiao Wei, Qi An, Yan Wang, Maoying Li, et al.
…omarkers, such as the neutrophil-to-albumin ratio (NAR), in pediatric populations has not been extensively investigated. This study sought to assess the association between NAR and pulmonary cavitation in children and adolescents with active pulmonary tuberculosis (PTB), as well …
Kexin Yang, Yang Zhang, Menghui Duan, Qiuju Liang, Jianfei Zhang, et al.
…y of suction tubes with markings in mechanically ventilated pediatric patients. Materials and Methods: A randomized assignment was carried out on a cohort of 52 pediatric patients who underwent mechanical ventilation in the Pediatric Intensive Care Unit at the Third Affiliated Ho…