Showing 126–150 of 200 documents
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Bilal Aslam, Faiza Farooq, Shafiq Ur Rahman, Fazeela Bibi, Umama Alam, et al.
Spinal tuberculosis, also known as Pott's disease, in children is a rare manifestation of extrapulmonary tuberculosis. The nonspecific clinical features, such as chronic abdominal pain, of extrapulmonary TB or spinal TB in children tend to delay diagnosis. We present the case of …
Kalawadia D, Gandhi D, Dirkhipa TY, Jaiswal A, Shah D, et al.
Aim To determine the bacteriological conversion rate after 6 months of Delamanid (DLM) based treatment in children with drug-resistant tuberculosis (DR-TB) and determine factors associated with bacteriological conversion. Methods This is a descriptive retrospective study done in …
Faverio P, Zanini U, Monzani A, Parati G, Luppi F, et al.
Sleep-disordered breathing (SDB) comprises different diseases characterized by abnormal respiratory patterns during sleep including obstructive sleep apnea. SDB prevalence and impact in patients with chronic respiratory infections have been only marginally studied. The purpose of…
Lee WL, Azmi A, Fadzlishah Johanabas R
Ventriculoperitoneal shunt (VPS) is a common procedure in neurosurgery for Cerebrospinal Fluid (CSF) diversion. It is associated with various complication. One of the rarer complications is migration of the shunt catheter. The incidence is higher in the paediatric population, up …
Bharatkumar Balkrishna Pandya, Andrea Nath Shogan
Abstract Pott’s disease is a form of extrapulmonary tuberculosis (TB) affecting the spine. Approximately 10% of individuals with extrapulmonary TB will have skeletal manifestations with the most common area affected being the spine, followed by the hip and knee. Within the spine,…
Çay Ü, Alabaz D, Gündeşlioglu ÖÖ, Mirioglu A, Pehlivan UA
Background Skeletal tuberculosis is rarely seen among extrapulmonary tuberculosis, especially in childhood because the diagnosis may be delayed for years due to diagnostic difficulties. In this study, it was aimed to evaluate the clinical characteristics, methods used in diagnosi…
Alejandro Rojas Urrea, Daniela Marino, Ana María Rojas-Faura, Mónica Liseth Holguín Barrera, Lorena García Agudelo
Tuberculosis is known as “the great mimicker.” Extrapulmonary tuberculosis accounts for approximately 20% of all cases, with about 10% of these involving the intestines. The ileocecal region is the most common site due to its high density of lymphoid tissue, slowed intestinal tra…
Ranti Dewanti Oktaviani, Pudji Lestari, Daniel Maranatha, Retno Asih Setyoningrum
Highlight: Pediatric tuberculosis patients profile using the medical records was determined.The most pediatric tuberculosis patients under five years have pulmonary tuberculosis.Pediatric tuberculosis patients received BCG immunization had a contact with adult tuberculosis patien…
Shyama S, Ojha VS, Biswas R, Luv L, Kaur G, et al.
…re divided into four categories: PTB adult, EPTB adult, PTB pediatrics, and EPTB pediatrics. Forty-nine patients in each category were selected, resulting in a total of 196 patients. The sample size was met via convenience sampling. A total of 27 parameters were compared. Mann-Wh…
Lucy Jefferson, Harry Petrushkin, Garth Dixon, Seilesh Kadambari
The management of pediatric eye infections can be highly challenging due to a range of clinical (often acute and rapidly deteriorating vision), diagnostic (inability to take appropriate samples from the infected eye) and treatment (limited data to support efficacy and potential t…
Fazal‐e‐Rabi Subhani
…unda, Dublin, Ireland. His main works are into the field of pediatrics and he has published many articles for the same. Speaker Publications: 1. Thwaites GE, Nguyen DB, Nguyen HD, et al. Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N Engl J…
du Preez K, Jenkins HE, Donald PR, Solomons RS, Graham SM, et al.
…et there are currently no estimates of the global burden of pediatric TBM. Due to frequent non-specific clinical presentation and limited and inadequate diagnostic tests, children with TBM are often diagnosed late or die undiagnosed. Even when diagnosed and treated, 20% of childr…
Dong-Mei Wang, Qi An, Qing Yang, Yi Liao
…med to investigate the prevalence of TB/HIV co-infection in pediatric TB patients in southwest China and its associated variables. **METHODS:** Pediatric TB patients were recruited from January 2014 to September 2024 in southwest China, based on etiology or clinical confirmation…
Chiara Tersigni, Luisa Galli
…o identify biomarkers of TB “resistance”, especially in the pediatric age. Basu Roy et al. recently published on EBioMedicine a study on a cohort of Gambian pairs of children (n = 58) exposed to the same index case with different infection status (infected and uninfected). This s…
Md Mayin Uddin Hasan, Mohammad Injamul Hoq, Saifur R Chowdhury
…im to estimate the pooled proportions of PTB and EPTB among pediatric and adult diagnosed tuberculosis cases in Bangladesh, and to summarize the associated factors. **METHODS:** We searched PubMed, Scopus, Cochrane Library, and BanglaJOL to retrieve articles published between Ja…
Dhruv Gandhi, Viren Amesur, Aditi Gupta, Minnie Bodhanwala, Ira Shah
A bstract Background: Conventional first-line regimens for pediatric central nervous system tuberculosis (CNS-TB) have been associated with poor clinical outcomes. In view of their bactericidal effect and high penetration rates into the CNS, ethionamide and ofloxacin may improve …
Christine Basanti, Sonia A. El-Saiedi, Mai Moawad, Azza Abdelmegeid
…ntry. Nevertheless, guidelines and studies for admission of pediatric TB cases are lacking in developing countries. Aim of the Work: To describe the clinical presentations of hospitalized pediatric TB cases. Materials and Methods: A retrospective analytical study of data collecte…
Imman Kalyani Jena, Sunil Kumar Agarwalla
…. Given the diagnostic complexity and potential severity of pediatric extrapulmonary TB, particularly in high-burden regions like India, it is crucial to better understand its clinical presentation and epidemiological profile. Objectives: This study aimed to evaluate the clinical…
Young Seok Seo, Ji‐Man Kang, Dong Soo Kim, Jong Gyun Ahn
…ld children with EPTB. Results: Exclusively on the basis of pediatric studies, 7 studies including 560 samples were selected. The pooled sensitivity and specificity of Xpert for all samples were 67% (95% CI 0.51-0.79) and 94% (95% CI 0.87-0.98), respectively. The area under the s…
Young Seok Seo, Ji‐Man Kang, Dong Soo Kim, Jong Gyun Ahn
…ds for <18-year-old children with EPTB. Results: In only pediatric studies, 8 studies including 652 samples were selected. The pooled sensitivity and specificity of Xpert for all samples were 71% (95% CI 0.63–0.79) and 97% (95% CI 0.95–0.99), respectively. The area under the s…
Seo YS, Kang JM, Kim DS, Ahn JG
…ltures or composite reference standards for Results In only pediatric studies, 8 studies including 652 samples were selected. The pooled sensitivity and specificity of Xpert for all samples were 71% (95% CI 0.63-0.79) and 97% (95% CI 0.95-0.99), respectively. The area under the s…
Haniyeh Esfandiar
…g countries, it is an uncommon cause of disseminated TB. In pediatric populations, particularly in the first and second decades of life, disseminated TB is often secondary to lung infections. However, there have been few reports of disseminated TB complicated by disseminated intr…
Ю. В. Мирончук, О. О. Пушнова, Л. В. Таран, Л. І. Чернишова, О. В. Двізов
…-resistant tuberculous meningitis in a child treated in the Pediatric Unit at the clinical base of the Department of Phthisiology and Pulmonology of Zaporizhzhia State Medical and Pharmaceutical University, located at the Public Non-Profit Enterprise “Zaporizhzhia Regional Clinic…
Dhruv Gandhi, Viren Amesur, Aditi Gupta, Minnie Bodhanwala, Ira Shah
Abstract Background Conventional first-line regimens for pediatric central nervous system tuberculosis (CNS-TB) consisting of isoniazid (H), rifampicin (R), pyrazinamide (Z), and ethambutol (E) have been associated with poor patient outcomes. In view of their bactericidal effect …
Jammula Mounika
…0% of childhood TB mortality. This case report focuses on a pediatric patient with obstructive hydrocephalus secondary to tubercular meningitis, complicated by pyrazinamide-induced hepatitis. The elevated dosages of essential antituberculosis agents for pediatric use, recommended…