Showing 126–150 of 192 documents
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Ponlagrit Kumwichar, Tagoon Prappre, Virasakdi Chongsuvivatwong
… conversion rates in a 60-day cluster randomized controlled trial with patients with pulmonary tuberculosis (VOT: n=63 and DOT: n=65) with positive sputum acid-fast bacilli smears and 38 observers equally randomized into the VOT and DOT groups (19 observers per group and n=1-5 pa…
Esmail A, Randall P, Oelofse S, Tomasicchio M, Pooran A, et al.
…is issue, we performed an open-label, randomized controlled trial in periurban informal settlements of Cape Town, South Africa, where we TB symptom screened 5,274 individuals using a community-based scalable mobile clinic. Some 584 individuals with HIV infection or symptoms of TB…
Saskia Janssen, Thanakorn Vongjarudech, Mats O Karlsson, Caryn M Upton, Anthony J Garcia-Prats, et al.
…upporting broader access to the 3HP regimen. **PAN AFRICAN CLINICAL TRIALS REGISTRY:** PACTR202306775627089, registration date June 15, 2023.
Le Wang, Hongsheng Wang, Liangbin Yan, Meiwen Yu, Jun Yang, et al.
…ing. METHODS: We conducted a cluster-randomized, controlled trial to investigate whether single-dose rifapentine is effective in preventing leprosy in household contacts of patients with leprosy. The clusters (counties or districts in Southwest China) were assigned to one of thre…
Goyal JP, Singh S, Bishnoi R, Bhardwaj P, Kaur RJ, et al.
…osis (TB). However, the evidence from randomized controlled trials (RCTs) is inconsistent. Objectives This systematic review and meta-analysis was performed to synthesize evidence regarding role of vitamin D versus placebo for the management of TB. Materials and methods We search…
Marks GB, Nguyen NV, Nguyen PTB, Nguyen TA, Nguyen HB, et al.
…ress. Methods We performed a cluster-randomized, controlled trial in Ca Mau Province, Vietnam, to evaluate the effectiveness of active community-wide screening, as compared with standard passive case detection alone, for reducing the prevalence of tuberculosis. Persons 15 years o…
Jackson-Morris A, Masyuko S, Morrell L, Kataria I, Kocher EL, et al.
…eb of Science, EMBASE, Global Health Database, and selected clinical trials registries. Eligible studies were published between 2010 and December 2022, available in English, and report health service delivery programs or policies for the selected disease dyads in LMICs. We identi…
Adrienne Katrin M Guiang-Valerio, Ma Theresa M Collante, Christine B Bernal
…re warranted to optimize pediatric treatment strategies. **CLINICAL TRIAL REGISTRY NAME AND REGISTRATION NUMBER:** N/A. **SUPPLEMENTARY INFORMATION:** The online version contains supplementary material available at 10.1186/s41927-026-00630-2.
Singh A, Midha V, Kaur K, Mahajan R, Singh D, et al.
…e for induction of remission at 8 weeks. Trail registration Clinical Trials Registry of India [CTRI/2021/10/037641].
Menghang Wu, Xiaorong Yin, Maojun Chen, Yan Liu, Xia Zhang, et al.
…long-term prognosis.The study was registered in the Chinese Clinical Trial Registry on May 16, 2015 (ChiCTR-IOR-15006441).
Juan Víctor Ariel Franco, Maria-Intí Metzendorf, Agostina Risso, Melanie Boeckmann, Sabrina Schlesinger, et al.
… WHO Global Index Medicus, as well as the WHO International Clinical Trials Registry Platform (ICTRP) on 3 May 2023 (date of last search for all databases). We placed no restrictions on the language of publication. Selection criteria: We included retrospective and prospective coh…
Franco JV, Bongaerts B, Metzendorf MI, Risso A, Guo Y, et al.
… WHO Global Index Medicus, as well as the WHO International Clinical Trials Registry Platform (ICTRP) on 3 May 2023 (date of last search for all databases). We placed no restrictions on the language of publication. Selection criteria We included retrospective and prospective coho…
Marcy O, Wobudeya E, Font H, Vessière A, Chabala C, et al.
…ortality. Methods We did a stepped-wedge cluster-randomised trial in 16 hospitals from six countries (Cambodia, Cameroon, Côte d'Ivoire, Mozambique, Uganda, and Zambia) with high incidence of tuberculosis. Children younger than 5 years with WHO-defined severe pneumonia received e…
Stephanie Bjerrum, Bada Yang, Johanna Åhsberg, Laura Olbrich, Mathias Weis Damkjær, et al.
…used in isolation for the detection of tuberculosis, but in clinical practice the tests may be used in parallel (i.e. LC-aNAAT in combination with LF-LAM). **OBJECTIVES:** To compare the diagnostic accuracy of the parallel use of LC-aNAAT on respiratory samples and LF-LAM on uri…
Saidi SS, Abdul Manaf R
…s and methods A single-blinded, randomized controlled field trial study design was conducted in Melaka from September 2019 until August 2021, involving newly diagnosed PTB patients. The participants were randomized either into the intervention group (FASTEN intervention) or into …
Manon Lounnas, Eden Ngu Masama, Samuel Beneteau, Kunda Kasakwa, Rodney Kaitano, et al.
…d questionnaire at all sites. This study is registered with ClinicalTrials.gov (NCT04203628) and the Pan African Clinical Trial Registry (PACTR202006814433059). **FINDINGS:** Of the 216 children enrolled between Jan 13, 2020, and Dec 31, 2021, 215 were included in the study and …
Anthony Harries, Kudakwashe C Takarinda
…ress.METHODS: We performed a cluster-randomized, controlled trial in Ca Mau Province, Vietnam, to evaluate the effectiveness of active community-wide screening, as compared with standard passive case detection alone, for reducing the prevalence of tuberculosis. Persons 15 years o…
Menghang Wu, Xiaorong Yin, Maojun Chen, Yan Liu, Xia Zhang, et al.
…long-term prognosis.The study was registered in the Chinese Clinical Trial Registry on May 16, 2015 (ChiCTR-IOR-15006441).
Menghang Wu, Xiaorong Yin, Maojun Chen, Yan Liu, Xia Zhang, et al.
…long-term prognosis.The study was registered in the Chinese Clinical Trial Registry on May 16, 2015 (ChiCTR-IOR-15006441).
Camila Massae Sato, Omar Ariel Espinosa, Gutembergue Santos de Sousa, Fabiane Verônica da Silva, Roberta Olmo Pinheiro, et al.
…ntacts of multibacillary leprosy cases. </sec> <sec> <title>CLINICALTRIAL</title> Brazilian Registry of Clinical Trials (ReBEC), RBR-6yg2z9. Retrospectively registered on 3 de Out. de 2019. </sec>
Stefan Fabian Weber, Anne Glaser, Bayodé Roméo Adegbite, Jabar Babatunde Pacome Agbo Achimi Abdul, Guy Arnault Rogue Mfoumbi Ibinda, et al.
…uartile range 28-57). PTB was confirmed in 34 of 103 (33%), clinically diagnosed in 5 of 103 (5%), and not diagnosed in 62 of 103 (62%). In the non-TB group, CXR findings were consistent with bacterial pneumonia (24/62, 39%) or malignancy (12/62, 19%). At follow-up, 81 of 100 (81…
Singh S, Diwakar A, Singh RK
… withdrawal of BCG vaccination mandates from developed industrialized countries while reducing to a single neonatal shot in the rest. Concurrently, a steady increase in early childhood Brain and CNS (BCNS) tumors has occurred. Though immunological causes of pediatric BCNS cancer …
Bogers SJ, Schim van der Loeff MF, Davidovich U, Boyd A, van der Valk M, et al.
…iated with a prevalence of undiagnosed HIV > 0.1%, or whose clinical management would be impeded if an HIV infection were undiagnosed. IC-guided HIV testing is an effective strategy in identifying undiagnosed HIV, but opportunities for earlier HIV diagnosis through IC-guided test…
Story A, Aldridge RW, Smith CM, Garber E, Hall J, et al.
…icentre, analyst-blinded, randomised controlled superiority trial in 22 clinics in England (UK). Eligible participants were patients aged at least 16 years with active pulmonary or non-pulmonary tuberculosis who were eligible for DOT according to local guidance. Exclusion criteri…
Jane E. Gross, Silvia M. Caceres, Katie R. Poch, Nabeeh A. Hasan, Rebecca M. Davidson, et al.
…rol guidelines. This study will systematically characterize clinically-relevant NTM isolates of CF healthcare environmental dust and water biofilms and set the stage to describe the most common environmental sources within the healthcare setting harboring clinically-relevant NTM …