Showing 126–132 of 132 documents
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David Chisompola, Christabel Mulenga, Kingsley Tembo, Nswana Mukuma, Elijah Chinyante
… analysis was carried out using the Statistical Package for Social Sciences (SPSS) version 22. Results: The study found an overall TB prevalence of 12% (95% CI: 11.15%–12.86%) among 5,590 participants, with RR-TB detected in 2.98% of cases. RR-TB prevalence was highest among male…
Horter S, Achar J, Gray N, Parpieva N, Tigay Z, et al.
Introduction Standard multidrug-resistant tuberculosis (MDR-TB) treatment is lengthy, toxic, and insufficiently effective. New drugs and a shorter treatment regimen (SCR) are now recommended. However, patient and health-care worker (HCW) perspectives regarding the SCR are unknown…
Gustavo E Velásquez, MD, MPH
PRISM-TB is an international, seamless, multicenter, open-label, randomized, controlled, pragmatic, stratified medicine, treatment shortening, multi-arm multi-stage (MAMS), noninferiority Phase 2/3 clinical trial for fluoroquinolone-susceptible multidrug-resistant/rifampin-resist…
Э.Б. Цыбикова, Д.А. Мидоренко, И. С. Лапшина, Mikhail Kotlovsky
Significance. In Russia, from 2001 to the beginning of the Covid-19 pandemic, the incidence of tuberculosis was decreasing on an annual basis, equaling to 41.2 per 100,000 population in 2019 (87.1 per 100,000 population in 2001). At the same time, the Covid-19 pandemic, which las…
Taipei Medical University WanFang Hospital
To assess outcome of treatment and safety among patients with rifampicin-resistant isoniazid-susceptible pulmonary tuberculosis treated with a novel regimen consisting of isoniazid, bedaquiline, and moxifloxacin throughout for 6 months, supplemented by pyrazinamide for the initia…
Muhammad Jauhar Fu'adi, Bagoes Widjanarko, Martini Martini
MDR TB disease occurs due to treatment failure, non-compliance in maintaining treatment so as to cause treatment interruption, improper treatment resulting in primary resistance. MDR TB treatment requires a longer treatment time, so the treatment time will cause various kinds of …
Widya Lita Fitrianur, Wiwik Widiyawati, Ervi Suminar
… appearance so that it has an impact on the patient's psychosocial condition, including the emergence of anxiety and depression. Anxiety and depression in MDR-TB patients have an impact on the patient's rejection of the diagnosis and they choose to stop the treatment process. The…