Showing 101–125 of 200 documents
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Jain A, Lodha R
Tuberculosis (TB), once widely prevalent throughout the world, experienced falling incidence rates in early twentieth century in developed nations, even before the introduction of anti-TB drugs, attributed to improved hygiene and living conditions. Active TB may develop following…
Hormi M, Guérin-El Khourouj V, Pommelet V, Jeljeli M, Pédron B, et al.
…kground Data regarding the use of QuantiFERON to assist the diagnosis of active tuberculosis (TB) in HIV-infected children are limited, especially in countries with low incidence of TB/HIV coinfection. Methods QuantiFERON results were analyzed in 63 HIV-infected children who pres…
Sheila Alexandra Regina Kort, Jayant Kalpoe, F.A. Gopie
Background: Latent tuberculosis can progress to active TB. To diagnose LTBI the TST is used, which shows cross reactivity with NTM and BCG, giving way to overdiagnosis of LTBI. The sophisticated QFT is also used to diagnose LTBI and hardly has cross reactivity. Based on previous …
Ariadna Guinea Lagunes, Marta Ponce, E Contreras Aviles, G. Prado, Ruy Perez, et al.
…logical therapies, increases the risk of infections such as tuberculosis (TB). QuantiFERON-TB Gold (QFT) is a diagnostic tool used to detect latent tuberculosis (LTBI) in immunosuppressed patients. Evaluating the prevalence of QFT positivity in IBD patients who are eligible for b…
Sailesh Shrestha
…kground Diabetes mellitus (DM) increases the risk of latent tuberculosis infection (LTBI) and its progression to active disease, leading to poorer treatment outcomes and higher relapse rates. Identifying and treating LTBI in people with DM offers a critical opportunity to reduce …
Boskovska K, Naceva-Fustic S, Simonovska L, Dilberovska M, Dacevski D, et al.
…This study aimed to evaluate the importance of IFN-γ in the diagnosis of pediatric TB and LTBI and to compare the IFN-γ levels. Methods We analysed 100 patients examined for possible M. tuberculosis infection or disease at the Institute of Respiratory Diseases in Children, Kozle,…
Yulia Yarovaya, Marina Lozovskaya, Elenа Vasil'eva, Lyudmila Klochkova, Gennadij Stepanov, et al.
…) in children, this study aimed to assess the likelihood of tuberculosis (TB) diagnosis in children with TB infection and positive ESAT-6/CFP-10 test results, alongside signs of vitamin D deficiency (clinical rickets and/or low serum vitamin D levels). **METHOD:** A total of 98 …
I Izanna, S Mohamad Ikhsan, M Mariam, I Siti Hasmah
…ing of healthcare providers and public education to support diagnosis, prevent outbreaks, and avoid complications. Digitalisation of health records, such as the documentation of vaccination history, is needed. CONCLUSION: Measles in Selangor showed age-specific trends and differe…
López-Suárez A, Santos-Sebastián M, Hernanz-Lobo A, Rincón-López E, Aguilera-Alonso D, et al.
Introduction Immune-based diagnostic tests for tuberculosis (TB) have suboptimal sensitivity in children and cannot differentiate between latent infection (LTBI) and active disease. This study evaluated the diagnostic potential of a broad range of biomarkers of tissue damage and …
Tabatneck ME, He W, Lamb GS, Sun M, Goldmann D, et al.
…ys (IGRAs) are approved for children ≥2 years old to aid in diagnosis of Mycobacterium tuberculosis (TB) infection and disease. Tuberculin skin tests (TSTs) continue to be the recommended method for diagnosis of TB infection in children Methods We performed a retrospective cohort…
Universidad Peruana Cayetano Heredia
…mpact of climate change on endemic infectious diseases (eg. Tuberculosis, Dengue Fever, Chagas Disease, and others). ABSTRACTS: 1. Decoding the Language of Tumor–Immune Communication: The Role of Extracellular Vesicles in Melanoma 2. The effect of lead (Pb) on the immune response…
Ribhav Gupta, D.K. Winslow, Ronit Gupta, Sten H. Vermund
…oms Enforcement (ICE) are likely at higher baseline risk of Tuberculosis (TB) and HIV. Per ICE guidelines, TB screening is mandated on intake with no routine HIV testing protocols. This study explores TB and HIV epidemiology across ICE facilities from 2019-2023. Three month slidi…
Surve S, Bhor V, Naukariya K, Begum S, Munne K, et al.
…[interferon gamma (INF-γ) release assays (IGRA)] for latent tuberculosis infection (LTBI) diagnosis among under-five children who are undernourished and/or who have history of contact with active tuberculosis (TB) patients. Methods Children from the age group of 6 months to 5 yea…
I. M. Poiasnyk
…f corticosteroids in therapy cause the activation of latent tuberculosis infection and the rapid development of the disease when infected with mycobacterium tuberculosis.The results of presented clinical case have shown that doctors of different specialties should be tuned to the…
Telefon AH, Cil MK, Sonmez G, Turgut EA, Gulmez TK, et al.
…o investigate the frequency and clinical characteristics of tuberculosis in pediatric patients receiving both anti-TNF-alpha and other biological agents. Materials and methods The data of 270 patients who used biological agents due to rheumatologic diseases and inflammatory bowel…
Turner NA, Ahmed A, Haley CA, Starke JR, Stout JE
…-gamma release assays (IGRAs) are widely used for detecting tuberculosis (TB) infection, tuberculin skin tests (TSTs) remain preferred for children under the age of 2 years. The preference for TST stems from concern over IGRA sensitivity in young children. However, TSTs are susce…
Buonsenso D, Delogu G, Del Carmen Pereyra Boza M, De Maio F, Palucci I, et al.
…QuantiFERON TB-Plus (QFT-Plus), are effective in aiding the diagnosis of tuberculosis (TB) infection but cannot distinguish latent TB subjects from active TB patients. The aim of this study was to prospectively evaluate the performance of an HBHA-based IGRA, combined with commerc…
Lombardi G, Pellegrino MT, Denicolò A, Corsini I, Tadolini M, et al.
…IT) assay, represent an important aid for diagnosing active tuberculosis (TB) and latent TB infections in children, but concerns about their use in children P P P < 0.0001). In summary, this study supports the use of QFT-IT as a complementary test for the diagnosis of pediatric T…
Vilma Lopes, Joana Pinho, Maria Adriana Rangel, Tânia Maria Rocha Guimarães, Isabel Carvalho
…a rare but challenging entity for paediatricians, regarding diagnosis and management. Treatment course is still up for discussion since tuberculomas may persist after treatment. The authors report two paediatric cases, both recently treated for latent tuberculosis infection, admi…
Nazan Dalgıç, Ayşe Şahin, Selda Hançerlı Törün, Özge Kaba, Pınar Önal, et al.
…udy aimed to investigate the frequency of latent and active tuberculosis (TB) in pediatric patients receiving anti-tumor necrosis factor (TNF)-α therapy. Methods Patients younger than 18 years with various inflammatory diseases and treated with anti-TNF-α agents in the past five …
Wang SH, Rajaram MVS, Trollip A, Wu Q, Ayala D, et al.
The diagnosis of latent tuberculosis (TB) infection (LTBI) is critical to improve TB treatment and control, and the T-SPOT. TB test is a commercial enzyme-linked immunosorbent spot assay used for this purpose. The objective of the study was to increase automation and extend the t…
Mellado-Sola I, Rodríguez-Molino P, Armas EA, Nogueira López J, Falces-Romero I, et al.
…screened for imported diseases with a unified protocol at a pediatric reference unit for tropical and infectious diseases in Madrid, Spain. We compared the pre-pandemic (2018-2019) and post-pandemic periods (2020-2021). Results A total of 192 minors were screened during the study…
María Eugenia Castellanos, Leonardo Martínez, Christopher C. Whalen
…rformance of interferon-gamma release assays (IGRAs) in the diagnosis of tuberculous infection in pediatric populations. The tuberculin skin test (TST) and IGRA tests have known limitations for the diagnosis of latent tuberculous infection (LTBI).2 We propose, as suggested by Goe…
Arnela Banićević, Amela Cerić, Zvjezdana Ritan Micic
An estimated 1.7 billion people are infected with the tuberculosis bacillus and are therefore at risk of developing tuberculosis. Globally, until the SarsCo-V2 pandemic, tuberculosis was the most common cause of infectious disease-related death. For women infected with Mycobacter…
Saborni Dey, Siddarath Kumar, Vivek Tyagi, Venkata Sai Charan
Background: Tuberculosis (TB) is a serious illness that mainly affects the lungs. The Mantoux tuberculin skin test (TST) is one method of determining whether a person is infected with Mycobacterium tuberculosis. Reliable administration and reading of the TST requires standardizat…