Showing 101–125 of 200 documents
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UNAIDS, PEPFAR, World Health Organization, World Health Organization
Anthony D. Harries, PhD, Huy Dung Nguyen, MD
The overall aim of the project is to evaluate rifabutin (RBT) as a replacement for rifampicin (RMP), for the combined treatment of tuberculosis and HIV infection. RBT represents an alternative to RMP for HIV infected patients as its half-life is longer and the enzymatic induction…
World Health Organization, UNAIDS, Global Fund to Fight AIDS, Tuberculosis and Malaria, United Nations Children's Fund (UNICEF)
World Health Organization
Anthony D Harries, MD, PhD, Alexander PYM, MD
The overall aim of the project is to evaluate rifabutin (RBT) as a replacement for rifampicin (RMP), for the combined treatment of tuberculosis and HIV infection. RBT represents an alternative to RMP for HIV infected patients as its half-life is longer and the enzymatic induction…
World Health Organization
Tapiwa Kumwenda, Veronica Phiri, Kelvin Rambik, Bianca Sossen, Tamiwe Tomoka, et al.
**BACKGROUND:** Enlarged lymph nodes (LN) pose diagnostic challenges for people with HIV (PWH). While tuberculosis (TB) is a common cause in low-income settings, lymphomas and Kaposi's sarcoma must also be considered. Ultrasound and symptoms cannot distinguish between these condi…
Lisa Puchalski Ritchie
Despite increased emphasis on evidence based practice in recent years a gap remains between evidence and practice, particularly in resource poor countries. Few studies to date have examined the use of knowledge translation strategies to improve health care outcomes in low income …
Mchunu NN, Mwambi HG, Rizopoulos D, Reddy T, Yende-Zuma N
Background The association structure linking the longitudinal and survival sub-models is of fundamental importance in the joint modeling framework and the choice of this structure should be made based on the clinical background of the study. However, this information may not alwa…
Lwin N, Boyle M, Davis JS
Corticosteroids are the mainstay of therapy for immune reconstitution inflammatory syndrome (IRIS). However, little is known about how to treat IRIS unresponsive to steroids. We report a patient with HIV-TB coinfection who was unresponsive to first prednisolone and then inflixima…
UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Stop TB Partnership
Saskia Janssen, Zul Izhar Mohd Ismail, Thomas Lovelock, Sarah Hugo, Marije Van Schalkwyk, et al.
Contains fulltext : 322446.pdf (Publisher’s version ) (Open Access)
Lungu P, Mushota K, Njelesani E, Sukwa T, Lakhi S, et al.
Background Mycobacterium tuberculosis (TB) remains a disease of global health concern and a leading cause of mortality arising from an infectious agent. Protective immunity to TB remains unclear. Suppressor of cytokine signaling-3 (SOCS3) and signal transduction and activator of …
Zeleke A, Misiker B, Yesuf TA
Objectives Anti-tuberculosis drug-induced hepatotoxicity is a common serious adverse drug reaction. This study intended to determine the prevalence and associated factors of drug-induced hepatotoxicity among tuberculosis and human immunodeficiency virus co-infected patients in De…
López, Rafael Alberto, Migliori, Giovanni Battista, Bergström, Karin, Norval, Pierre-Yves, World Health Organization, et al.
World Health Organization
World Health Organization
Belén Saavedra, Mariana G. López, Álvaro Chiner‐Oms, Ana María García García, Irving Cancino‐Muñoz, et al.
Abstract Genomic studies of Mycobacterium tuberculosis complex (MTBC) might shed light on the dynamics of its transmission, especially in high-burden settings, where recent outbreaks are embedded in the complex natural history of the disease. We applied Whole-genome sequencing (W…
World Health Organization. Regional Office for the Western Pacific
World Health Organization
World Health Organization, UNAIDS, International Labour Organization
Gengiah S, Connolly C, Yende-Zuma N, Barker PM, Nunn AJ, et al.
Background A quality improvement (QI) collaborative approach to enhancing integrated HIV-Tuberculosis (TB) services may be effective in scaling up and improving the quality of service delivery. Little is known of the role of organizational contextual factors (OCFs) in influencing…
Maji D, Agarwal U, Kumar L, V V, Sharma A
The risk of death in HIV-TB coinfected individuals is far greater than in HIV-only patients. It is critical to provide timely and appropriate therapy in HIV-TB coinfected patients in order to reduce morbidity and mortality. The purpose of this study was to evaluate the clinical p…
Tesfaye B, Alebel A, Gebrie A, Zegeye A, Tesema C, et al.
Background Tuberculosis and HIV/AIDS are the major public health problems in many parts of the world particularly in resource limited countries like Ethiopia. Although studies have been conducted on the prevalence and associated factors of TB / HIV co-infection in Ethiopia, there…
Endeshaw Habtamu Wolelaw, Endalk Getasew Hiruy, Asiya Mohammed Abdu, Kebadnew Mulatu Mihretie
**BACKGROUND:** In patients who have tuberculosis and the human immunodeficiency virus, Tuberculosis is the most prevalent opportunistic illness and the main cause of death. However, little is currently, the time to death and its predictors are known, particularly among individua…