Showing 101–125 of 200 documents
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Jiayun Liu, Fengjuan Wang, Xiaoyan Hao
…atic diseases is a contributing factor to the occurrence of tuberculosis (TB) infection. The primary objectives of this investigation were to examine the risk factors associated with the advancement of rheumatic diseases in conjunction with latent tuberculosis infection (LTBI) le…
Yong Li, Linlin Song, Ying Zhang, Zhenzhou Feng, Feng Sun, et al.
…or distinguishing healthy individuals and those with latent tuberculosis infection from patients with active tuberculosis, but their changes during the treatment process have been rarely studied, especially in the context of drug-resistant tuberculosis treatment. Methods: This st…
Tsolaki AG, Varghese PM, Kishore U
Innate immunity against Mycobacterium tuberculosis is a critical early response to prevent the establishment of the infection. Despite recent advances in understanding the host-pathogen dialogue in the early stages of tuberculosis (TB), much has yet to be learnt. The nature and c…
Miyazaki S, Fujita K, Ozaki S, Ichiyama S, Ito M, et al.
…is generally effective in preventing reactivation of latent tuberculosis infection (LTBI), prophylactic measures do not fully protect against development of active tuberculosis. We report a rare case of active tuberculosis despite chemoprophylaxis for LTBI in a patient receiving …
Stidham RA, Tyler RG
Tuberculosis (TB) remains a force health protection threat to the U.S. military, particularly in crucial populations at increased risk of exposure or re-activation. This analysis examined TB testing trends and the prevalence of latent tuberculosis infection (LTBI) among U.S. Army…
Ralph A Stidham, Rachel G Tyler
Tuberculosis (TB) remains a force health protection threat to the U.S. military, particularly in crucial populations at increased risk of exposure or re-activation. This analysis examined TB testing trends and the prevalence of latent tuberculosis infection (LTBI) among U.S. Army…
Iba A, Tomio J, Yamana H, Sugiyama T, Yoshiyama T, et al.
Background and aim Screening for tuberculosis before treating with biologic agents is recommended in patients with immune-mediated inflammatory diseases (IMIDs). We conducted this study to identify adherence to the recommended practice in a real-world setting in Japan. Methods We…
Mufradul Islam Rafi, Fahmida Rahman, Sraboni Mazumder, Maksurat Zereen Khan, Avizit Sarker, et al.
Abstract Individuals with latent tuberculosis infection (LTBI) are possible reservoirs for active tuberculosis. Currently, TST and IGRA are used to diagnose LTBI, but neither can distinguish between active TB and LTBI. The purpose of this study was to assess serum miRNA-144-3p's …
Haerana BT, Prihartono NA, Riono P, Djuwita R, Syarif S, et al.
Background Children who inhabit the same house with tuberculosis (TB) patients are at high risk for infection and illness with TB. Nutritional status (stunting) in children is related to the child's ability to withstand MTB (Mycobacterium Tuberculosis). This study aims to estimat…
Achkar JM, Prados-Rosales R
A more effective vaccine to control tuberculosis (TB), a major global public health problem, is urgently needed. Current vaccine candidates focus predominantly on eliciting cell-mediated immunity but other arms of the immune system also contribute to protection against TB. We rev…
Mustafa As
The worldwide control of tuberculosis (TB) requires affordable and easy to apply test(s), which could diagnose active/latent TB and differentiate from vaccination with Mycobacterium bovis Bacillus Calmette Guerin (BCG), and exposure to environmental mycobacteria. The currently us…
Sharma S, Bhat R, Singh R, Sharma S, Wazir P, et al.
One of the significant challenges to treat tuberculosis is the phenotypic resistance adapted by the latent or dormant Mycobacterium tuberculosis (M. tuberculosis) cells against most of the available drugs. Different in-vitro assay such as oxygen depletion model and nutrient starv…
Çavuşoğlu C, Çoğulu Ö, Durmaz A, Cengisiz Z, Yılmaz FF, et al.
… of the miRNA and cytokine expression levels, the course of tuberculosis infection, clinical forms and response to treatment, and (ii) the effects of genotypic features of bacteria on the course of tuberculosis and the relationship between miRNA and cytokine expressions and bacte…
López-Ramos JE, Macías-Segura N, Cuevas-Cordoba B, Araujo-Garcia Z, Bastián Y, et al.
Background Pulmonary tuberculosis (PTB) is a public health problem with 10.4 million new cases reported in 2017 (1). According to the World Health Organization (WHO), accurate diagnostic tests based in serum biomarkers to detect new cases of tuberculosis are necessary. Aim of the…
Gong W, Liang Y, Wang J, Liu Y, Xue Y, et al.
Latent tuberculosis infection (LTBI) is the primary source of tuberculosis (TB) but there is no suitable detection method to distinguish LTBI from active tuberculosis (ATB). In this study, five antigens of Mycobacterium tuberculosis belonging to LTBI and regions of difference (RD…
Юлия Анатольевна Яровая, M. E. Lozovskaya, S. A. Krylova, O. P. Gurina, A. E. Blinov, et al.
Introduction. Vitamin D plays an important role in anti-tuberculosis immunity, and the reduction level of this vitamin in the body is critical. Aim . To estimate the probability of diagnosis of active tuberculosis in children with positive ATR-test and/or IGRA test results and di…
Kuscu F, Yildirim F, Erturk D, Cabalak M, Komur S, et al.
Background About 10% of individuals with latent tuberculosis infection (LTBI) develop tuberculosis (TB) disease during their lifetime. People living with HIV (PLWH) have a significantly higher risk of developing tuberculosis disease from latent tuberculosis infection (LTBI) compa…
Л. Н. Мотанова, M. N. Kudrya
…: to estimate the occurrence of clinical forms of childhood tuberculosis (TB) depending on BCG vaccination in regions with a high prevalence of TB. Materials and Methods . The research design is a retrospective continuous comparative study. We analyzed the data of registration fo…
Adankwah E, Lundtoft C, Güler A, Franken KLMC, Ottenhoff THM, et al.
…FERON (QFT)] are widely used for diagnosis of Mycobacterium tuberculosis ( Mtb ) infection. T-cell responses against QFT antigens ESAT6 and CFP10 are highly Mtb specific but previous studies indicated suboptimal assay sensitivity. Especially for potentially infected healthy conta…
Reece ST, Vogelzang A, Tornack J, Bauer W, Zedler U, et al.
Persistence of Mycobacterium tuberculosis within human bone marrow stem cells has been identified as a potential bacterial niche during latent tuberculosis. Using a murine model of tuberculosis, we show here that bone marrow stem and progenitor cells containing M. tuberculosis pr…
Thomas B Nutman, M.D.
Background: Tuberculosis (TB) is a severe disease and a major cause of death in many people worldwide. It is caused by a bacteria that enters through the lungs and can spread elsewhere in the body. People with latent TB have the bacteria that lie dormant but can become active an…
Feng PI, Horne DJ, Wortham JM, Katz DJ
Objective Little is known about regimen choice for latent tuberculosis infection in the United States. Since 2011, the Centers for Disease Control and Prevention has recommended shorter regimens-12 weeks of isoniazid and rifapentine or 4 months of rifampin-because they have simil…
Digambar Behera
…. However, the association and effect of COVID-19 vis-a-vis tuberculosis (TB) on each other is not clearly understood and experience on COVID-19 in TB patients is limited. There are many similarities and differences between the two diseases. Some limited and preliminary observati…
Juste RA, Fernández-Veiga L, Fuertes M, Fernández-Ortiz de Murua I, Cardona G, et al.
Tuberculosis (TB) is a disease caused by members of the M. tuberculosis complex (MTC) that affects numerous species. M. caprae, a member of the complex which is close to M. bovis, is emerging and affects several different hosts that include goats, cattle, sheep, pigs, rabbits, wi…
Florence Mutua, Ruey-Chyi Su, Terry Blake Ball, Sandra Kiazyk
…ype I interferon-induced transcriptomic signature in active tuberculosis suggests a potential role for these interferons in the pathogenesis of tuberculosis. Comorbidities such as human immunodeficiency virus, diabetes, systemic lupus erythematosus, end-stage renal disease, and c…