Showing 101–125 of 200 documents
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Diriba G, Alemu A, Eshetu K, Yenew B, Gamtesa DF, et al.
…actual burden of bacteriologically confirmed extrapulmonary tuberculosis (EPTB) and risk factors in Ethiopia is not well known due to the lack of a strong surveillance system in Ethiopia. Thus, this study was conducted to estimate the pooled prevalence of bacteriologically confir…
Khannara Kheng, Sophana Sam, Silab Ong, Sikheang Chhiv, Sear Soun, et al.
Tuberculosis is a kind of serious physical disorder which not only affects human organs (pulmonary and extrapulmonary) but also causes psychological disorders. This study investigated the prevalence of anxiety and depression among tuberculosis TB inpatients at the National Tuberc…
He Y, Lyon CJ, Nguyen DT, Liu C, Sha W, et al.
Diagnosis of pediatric tuberculosis (TB) is often complicated by its nonspecific symptoms, paucibacillary nature, and the need for invasive specimen collection techniques. However, a recently reported assay that detects Mycobacterium tuberculosis virulence factors in serum can di…
Tada Ogie Ehondor, Ephraim Ehidiamen Ibadin
There is paucity of data on extrapulmonary tuberculosis (EPTB) subsets in Nigeria despite contributing to the burden of tuberculosis. This study investigated extrapulmonary tuberculosis (EPTB) among tuberculosis (TB) suspects presenting at a tertiary health facility in Benin City…
Faungchat Thammarakcharoen, Autcharaporn Srion, Watchara Chokevivat, Ruedee Hemstapat, Noppawan Phumala Morales, et al.
Bone and joint tuberculosis is one of extrapulmonary tuberculosis that is commonly found globally. Treatment of bone tuberculosis typically involves long term oral medication and frequently causes side effects due to its systemic administration route. In order to mitigate the sid…
Ji‐Won Park, Kyoung Sim Kim, Yong Wook Kim, Eun Young Kim, Young Ju Kim, et al.
Congenital tuberculosis infection is very rare, but fatal. Congenital tuberculosis should always be considered among the many causes of pneumonia, especially if the newborn has pneumonia that does not respond to treatment. We report a case of a premature infant born to a mother w…
Qiang Niu, Runrui Wu, Ke Pan, Xinlan Ge, Wen Chen, et al.
Hepatic tuberculosis (HTB) is rare extrapulmonary tuberculosis that is clinically similar to liver malignancy, making it difficult for correct diagnoses. Pathology is the gold standard for tuberculosis diagnosis. However, there are few reports on the pathological features of HTB.…
Herikurniawan Herikurniawan, Joanna Audrey, Mira Yulianti, N Indira, Cleopas Martin Rumende
Tuberculosis (TB) has become one of the global burdens of disease, with increasing morbidity and mortality every year. Tuberculosis can affect not only the lungs but also the extrapulmonary organs. The prevalence of drug-resistant tuberculosis (DR-TB) is rising and has caused a h…
Shanbag N, Haseeb M, Engade M, Siddiqui MS, Badaam KM, et al.
Background The prevalence of tuberculosis (TB) disease among household contacts of adult TB patients is very high. Contact screening and isoniazid preventive therapy (IPT) are recommended for household contacts, but their uptake by families and implementation by the national TB p…
Addo SO, Abrahams AOD, Mensah GI, Mawuli BA, Mosi L, et al.
…ity of immunohistochemistry (IHC) using anti- Mycobacterium tuberculosis antibody (ab905) for detecting the presence of mycobacterial antigens in archived formalin-fixed paraffin-embedded (FFPE) tissues. Methods FFPE tissues [surgical biopsies (n = 32) and post-mortem tissues (n …
Xichao Ou, Peilei Hu, Xundi Bao, Zhou Liu, Chong Teng, et al.
…ication and testing (AutoSAT) method in suspected pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) by comparing with Xpert MTB/RIF (Xpert) method against the composite reference standard. **METHOD:** Patients with suspected PTB or EPTB were enrolled consecutiv…
Aylin Var, Yusuf Uysal, Mehmet Kuruş, Yağmur Seda Yeşiltaş, Uğur Bozlar, et al.
PURPOSE: Orbital/periorbital tuberculosis (TB) is an uncommon manifestation of extrapulmonary TB, presenting diagnostic challenges due to its varied clinical features that can mimic other diseases. This report aims to present a rare case of periorbital TB in a young man. METHODS:…
International Journal of Medical Science and Advanced Clinical Research (IJMACR)
Abstract Introduction: Accurate and timely tuberculosis diagnosis is the primary step for initiating effective treatment. The colour plate agar-based culture test (TB-CX test) is a low cost, simple to use, detects Mycobacterium tuberculosis faster. The study conducted to compare …
International Journal of Medical Science and Advanced Clinical Research (IJMACR)
Abstract Introduction: Accurate and timely tuberculosis diagnosis is the primary step for initiating effective treatment. The colour plate agar-based culture test (TB-CX test) is a low cost, simple to use, detects Mycobacterium tuberculosis faster. The study conducted to compare …
Doctor Busizwe Sibandze, Beki Themba Magazi, Lesibana Anthony Malinga, Nontuthuko Excellent Maningi, Bong Akee Shey, et al.
… There is a general dearth of information on extrapulmonary tuberculosis (EPTB). We investigated Mycobacterium tuberculosis (Mtb) drug resistance and transmission patterns in EPTB patients treated in the Tshwane metropolitan, South Africa. Methods Consecutive Mtb culture-positive…
Scherer J, Mukasa SL, Wolmarans K, Guler R, Kotze T, et al.
Background Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb) and typically infects the lungs. However, extrapulmonary forms of TB can be found in approximately 20% of cases. It is suggested, that up to 10% of extrapulmonary TB affects the musculoskeletal system, in …
Sharma K, Sharma M, Ayyadurai N, Dogra M, Sharma A, et al.
…IF Ultra (Ultra) was evaluated for the first time on Ocular tuberculosis (OTB) samples and compared with Xpert. Methods Seventy five vitreous fluid samples (3 confirmed OTB, 47 clinically suspected OTB, and 25 controls) were subjected to Ultra, Xpert and Multiplex-PCR and compare…
S Sinha, A Ajayababu, R Titiyal, A Sinha, P R Mohapatra, et al.
Abstract Background Extrapulmonary tuberculosis (EPTB) constituting approximately one-fifth of the overall burden of tuberculosis (TB), is challenge both in terms of diagnosis due to lower rates of microbiological positivity and for treatment in terms of drug penetration, duratio…
Var A, Uysal Y, Kuruş M, Yeşiltaş YS, Bozlar U, et al.
Purpose Orbital/periorbital tuberculosis (TB) is an uncommon manifestation of extrapulmonary TB, presenting diagnostic challenges due to its varied clinical features that can mimic other diseases. This report aims to present a rare case of periorbital TB in a young man. Methods C…
Faksri K, Xia E, Ong RT, Tan JH, Nonghanphithak D, et al.
Tuberculous meningitis (TBM) is a severe form of tuberculosis with a high mortality rate. The factors associated with TBM pathogenesis are still unclear. Using comparative whole-genome sequence analysis we compared Mycobacterium tuberculosis (Mtb) isolates from cerebrospinal flui…
Sibandze DB, Magazi BT, Malinga LA, Maningi NE, Shey BA, et al.
… There is a general dearth of information on extrapulmonary tuberculosis (EPTB). Here, we investigated Mycobacterium tuberculosis (Mtb) drug resistance and transmission patterns in EPTB patients treated in the Tshwane metropolitan area, in South Africa. Methods Consecutive Mtb cu…
Ayu Rizky Widowati, I Wayan Agung Indrawan, Rezki Tantular
Introduction: Female Genital Tuberculosis (FGTB) is a rare but serious form of extrapulmonary tuberculosis that significantly impacts female reproductive health. It accounts for 15–20% of extrapulmonary TB cases and is found in 5–10% of infertile women. Diagnosis is often delayed…
Kim M, Lee JH, Lee HN, Park DJ, Lee EJ
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (MTB), can affect the lungs (pulmonary TB) as well as other sites (extrapulmonary TB). Nasopharyngeal tuberculosis (NPTB) is a rare type of extrapulmonary TB. Since NPTB has nonspecific clinical present…
Kaur K, Sharma S, Abhishek S, Kaur P, Saini UC, et al.
Objectives Bone tuberculosis (TB) is the third most common types of extrapulmonary tuberculosis. It is critical to understand mycobacterial adaptive strategies within bone lesions to identify mycobacterial factors that may have role in disease pathogenesis. Methods Whole genome m…
Human Sciences Research Council
…mmunopathology occurs in human immunodeficiency virus (HIV)/tuberculosis (TB) coinfection, but the underlying molecular mechanisms are not well-defined. Excessive matrix metalloproteinase (MMP) activity is emerging as a key process but has not been systematically studied in HIV-a…