Showing 76–100 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Anwaierjiang A, Wang Q, Liu H, Yin C, Xu M, et al.
Objective Drug-resistant tuberculosis is a major public health problem, especially in the southern region of Xinjiang, China; however, there is little information regarding drug resistance profiles and mechanism of Mycobacterium tuberculosis in this area. The aim of this study wa…
Iqbal A, Shafique M, Zahoor MA, Muzammil S, Nawaz Z, et al.
Introduction Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) is one of the leading causes of death in the world. The resource constraints make it difficult to diagnose and monitor the cases of MDR-TB. GeneXpert is a recognized tool used to diagnose the patients of pulmona…
Lu N, Yang Y, Liu J, Li J, Ouyang B, et al.
Tuberculosis is a devastating disease responsible for approximately 1.5 million deaths annually especially in developing countries. Although there is recommended and standard treatment for tuberculosis but the non-adherence of the patients to the lengthy treatment, adverse effect…
Mehta V, Ansari R, Shah I
Mixed tuberculosis occurs with multiple clonally distinct mycobacterium tuberculosis strains in an individual. We present a 12-year-old girl with steroid-resistant nephrotic syndrome and drug-sensitive pulmonary tuberculosis (Xpert MTB/Rif) and preextensively drug-resistant tuber…
Singh AV, Singh S, Yadav A, Kushwah S, Yadav R, et al.
…tic variability of drug resistant isolates of Mycobacterium tuberculosis is of paramount importance to understand transmission dynamics of disease and to improve TB control strategies. Despite of largest number of multidrug-resistant (MDR) tuberculosis cases (1, 30,000; 27% of th…
Setyawan MF, Mertaniasih NM, Soedarsono S, Nuha Z, Maladan Y, et al.
…ide and amino acid from rifampicin-resistant (RR) pulmonary tuberculosis (TB) patients, both new and relapse cases treated with Bdq. Methods This is an observational descriptive study performed in the referral hospital Dr Soetomo, Indonesia, at August 2022-November 2022. We perfo…
Soares VM, Almeida IN, Figueredo LJA, Haddad JPA, Oliveira CSF, et al.
…jective To evaluate the risk factors for the development of tuberculosis and multidrug-resistant tuberculosis (MDR-TB) in patients treated at a tertiary referral hospital. Methods This was a cross-sectional study based on data obtained from patients treated at the Júlia Kubitsche…
Choi YJ, Kim Y, Park HJ, Kim D, Lee H, et al.
Background The prevalence of multidrug-resistant tuberculosis (MDR-TB) among Korean tuberculosis patients is about 4.1%, which is higher than the OECD average of 2.6%. Inadequate drug use and poor patient compliance increase MDR-TB prevalence through selective pressure. Therefore…
Fahrur Rozi, Fakhrun Nisa’ Fiddaroini, Prawito Prawito
Background: Resistance of Mycobacterium Tuberculosis is a condition in which Anti-Tuberculosis (OAT) drugs are unable to kill the Mycobacterium Tuberculosis germs. One type of resistance is Multidrug Resistant Tuberculosis. Multidrug Resistant Tuberculosis (MDR-TB) is TB caused b…
Lobie TA, Woldeamanuel Y, Asrat D, Beyene D, Bjørås M, et al.
Introduction Tuberculosis (TB) remains a major global public health problem and is the leading cause of death from a single bacterium, Mycobacterium tuberculosis (MTB) complex. The emergence and spread of drug-resistant strains aggravate the problem, especially in tuberculosis hi…
Jabbar A, Phelan JE, de Sessions PF, Khan TA, Rahman H, et al.
Tuberculosis (TB), caused by Mycobacterium tuberculosis bacteria, is a leading infectious cause of mortality worldwide, including in Pakistan. Drug resistant M. tuberculosis is an emerging threat for TB control, making it important to detect the underlying genetic mutations, and …
Carter BB, Zhang Y, Zou H, Zhang C, Zhang X, et al.
We reviewed the records of 337 confirmed cases of tuberculosis patients in Monrovia, the capital of Liberia, 2015. The risk factors affecting the survival and multidrug-resistance of tuberculosis patients were examined. Kaplan-Meier analysis and the log-rank test were used to ass…
Ketema DB, Muchie KF, Andargie AA
Background Treatment of drug-resistant tuberculosis is often more complex and toxic with longer treatment time and poor treatment outcomes including treatment failure or death. Monitoring drug-resistant tuberculosis therapy including early identification of prognostic factors and…
Zereabruk K, Kahsay T, Teklemichael H, Aberhe W, Hailay A, et al.
Background Multidrug-resistant tuberculosis is a type of tuberculosis that is resistant to at least the first-line antituberculosis drugs namely, rifampicin and isoniazid. However, most of these studies were limited only to a single hospital. Therefore, this study aimed to identi…
T. A. Romanko, Ю. В. Корж, Ya. O. Proskurova
…rugs for the treatment of patients with multiple resistance tuberculosisinUkraine.Materials and methods. The Ministry of Health of Ukraine for the years 2014-2018 on the volume of public purchases of anti-tuberculosis medicines has been used for the study. The total amount of pub…
Dutt R, Singh R, Majhi J, Basu G
Context Tuberculosis (TB) is one of the main causes of death due to infectious diseases worldwide. Multidrug resistance/rifampicin resistance (MDR/RR) TB remains a public health crisis. India has the highest burden of tuberculosis and multidrug resistant TB (MDR TB) in the world.…
Indra Rahmad, Muhtar Muhtar, Maruni Wiwin Diarti, Julhana Julhana, Ahmad Ahmad
Tuberculosis is a chronic, infectious disease caused by the bacterium Mycobacterium tuberculosis and remains a global health problem, including in Indonesia. Worldwide, TB is one of the 10 leading causes of death. Poor adherence to treatment is a major obstacle to efficient TB co…
Montoya JC, Malabad JCM, Ang CF, Reyes LT, Basilio RP, et al.
Tuberculosis, caused by Mycobacterium tuberculosis, remains a high burden disease and leading cause of mortality in the Philippines. Understanding the genetic diversity of M. tuberculosis strains in the population, including those that are multi-drug resistant (MDR), will aid in …
Tatiana Umpeleva, Elena Mazurina, Leonid Lavrenchuk, Sven Gudmund Hinderaker, Einar Heldal, et al.
Background Nearly half of new tuberculosis patients in Sverdlovsk Oblast were diagnosed with multidrug-resistant tuberculosis (MDR-TB) and often exhibited fluoroquinolone resistance (FQ-R). This study aimed to (1) determine the number of MDR-TB patients who had Mycobacterium tube…
Muhammad Raihan Habibi, Arief Bakhtiar, Danti Nur Indiastuti, Resti Yudhawati Meliana
Multidrug-Resistant Tuberculosis (MDR TB) is a condition when Mycobacterium tuberculosis were resistant to Isoniazid and Rifampicin simultaneously, with or without being followed by other first-line Anti-Tuberculosis Drugs. Diabetic patients who also have TB are more susceptible …
Kassa M, Desta K, Ambachew R, Gebreyohannes Z, Gebreyohanns A, et al.
Background Mycobacterium tuberculosis (M. tuberculosis) remains one of the most significant causes of death and a major public health problem in the community. As a result, the aim of this study was to determine magnitude of Mycobacterium tuberculosis, its drug resistance, and as…
Forhad Akhtar Zaman, Vijay Mehta, Shraddha Deokota
BACKGROUND Tuberculosis (TB) is a curable and preventable disease. Emergence of multi drug resistance TB (MDR TB) threatens to undo the progress made towards control of TB. While treatment is available for MDR TB, it is of a long duration and is also more expensive and toxic. Und…
Gunawan, Koraag ME, Syahnuddin M, Nursafingi A, Nurjana MA, et al.
MDR-TB is a tuberculosis disease resistant to the two most effective anti-TB drugs, rifampin and isoniazid. MDR-TB is a threat to TB control. This study aims to identify the Mycobacterium tuberculosis strain in MDR-TB patients at Undata Hospital in Palu, Central Sulawesi. This ty…
Bhattacharjee A, Sarma S, Sen T, Singh AK
Background Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis, has plagued humans since the early middle-ages. More than one million deaths are recorded annually due to TB, even in present times. These deaths are primarily attributed to the constant app…
Behzadifar M, Martini M, Behzadifar M, Bragazzi NL
Tuberculosis is a serious respiratory infectious disease, caused by Mycobacterium tuberculosis bacteria. It has always represented a permanent, serious public health challenge over the course of human history, because of its severe epidemiological, clinical and societal implicati…