Showing 76–100 of 200 documents
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Victoria Male, Christine E Jones
…o the newborn, so an alternative strategy is vaccination in pregnancy. This approach has been successfully used to protect newborns against tetanus and pertussis, and vaccines that are primarily offered to protect the mother during pregnancy, such as influenza and COVID-19 vaccin…
Siddhartha Chatterjee, Bishista Bagchi, Rajib Gon Chowdhury, Abira Dutta
Background: Ectopic tubal pregnancy (ETP) is a dreadful situation for both the patient and the doctor. Prevalence of ETP is increasing because of availability of convenient and modern modalities for the diagnosis of ectopic pregnancy. Patients are aware of the condition and many …
Sotskiy PO, Sotskaya OL, Hayrapetyan HS, Sarkisian TF, Yeghiazaryan AR, et al.
…us, FMF and colchicine may potentially affect fertility and pregnancy in patients with FMF. The aims of the study are to evaluate the causes of infertility and pregnancy outcome in FMF patients and to compare them with 2 groups: non-FMF patients with peritoneal female genital tub…
Nyashadzaishe Mafirakureva, Anna Cartledge, Isobella Bradshaw, Adrie Bekker, Nicole Salazar-Austin, et al.
…, perinatal, and infant health risks of tuberculosis during pregnancy, global estimates of incidence remain scarce. Existing estimates are outdated, and do not include the postpartum period, HIV co-infection, age, or specific changes in risk, limiting our understanding of the tru…
Silvia S Chiang, Jonathon R Campbell, Daniele Maria Pelissari, Márcia C Bellotti de Oliveira, Anna Cristina C Carvalho, et al.
…rculosis (TB) annually. Little is known about the impact of pregnancy on TB outcomes. **METHODS:** This study used surveillance data from Brazil's Ministry of Health. We included women aged 11-49 years newly diagnosed with drug-susceptible TB disease between 2016 and 2022, treat…
Jennifer A Hughes, Flynn McMorrow, Kristina M Brooks, Mauricio Pinilla, Lee Fairlie, et al.
…re no published data on clofazimine pharmacokinetics during pregnancy, and safety data are limited. We present data from pregnant and postpartum women receiving clofazimine for treatment of rifampicin-resistant tuberculosis (RR-TB). **METHODS:** IMPAACT P1026s was an observation…
…berLeninka, the following terms were used: «tuberculosis», «pregnancy», «mycobacterium tuberculosis», «diagnosis», «treatment», «infertility», «postpartum period», «puerperants». 130 ref-erences were found and 50 articles selected. Results. Com-plaints in pregnant women with TB d…
Maulana Muharam, Dewi Wahyu Firina, Dessy Mizarti
…erse effect of drug, make it management become challenging. Pregnancy with physiological changes in it made pregnant woman susceptible to infection, include tuberculosis infection. Data about MDR TB in pregnancy were not much, because TB screening in pregnancy were not often done…
Van Schalkwyk M, Bekker A, Decloedt E, Wang J, Theron GB, et al.
Physiological changes during pregnancy may alter the pharmacokinetics (PK) of antituberculosis drugs. The International Maternal Pediatric Adolescent AIDS Clinical Trials Network P1026s was a multicenter, phase IV, observational, prospective PK and safety study of antiretroviral …
Igor Ivanes, Ecaterina Evstrati, Stela Kulciţkaia, Anastasia Ivanes
Pregnancy, childbirth and the postpartum period in women are factors that contribute to the appearance and exacerbation of tuberculosis. Accumulation in the blood of human chorionic gonadotropin, estrogen, glucocorticoids, aldosterone leading to disrupting hormonal balance and im…
Marije Van Schalkwyk, Adrie Bekker, Eric Decloedt, Jiajia Wang, Gerhard B Theron, et al.
…etics (PK) of antituberculosis drugs may be altered by both pregnancy-induced physiological changes and drug interactions in individuals living with HIV who develop tuberculosis. Within the multicenter International Maternal Pediatric Adolescent AIDS Clinical Trials Network P1026…
Maulana Muharam, Dewi Wahyu Firina, Dessy Mizarti
…erse effect of drug, make it management become challenging. Pregnancy with physiological changes in it made pregnant woman susceptible to infection, include tuberculosis infection. Data about MDR TB in pregnancy were not much, because TB screening in pregnancy were not often done…
Birku M, Desalegn G, Kassa G, Tegbaru B, Howe R, et al.
…infection and this suppression could further be enhanced by pregnancy. However, the effect of pregnancy on Mycobacterium tuberculosis (M. tuberculosis)-specific immune response during HIV/latent TB co-infection is not well understood. Here we investigated the changes in M. tuberc…
Hazenberg P, Navaratnam K, Busuulwa P, Waitt C
…bstantial anatomical and physiological changes occur during pregnancy and labor, which impact on drug absorption, distribution, metabolism, and elimination. Reduced maternal concentrations may have a clinically important impact on the efficacy of anti-infectives for mother, fetus…
О. М. Raznatovska, A.V. Fedorec, M. O. Shalmina, Тетяна Анатоліївна Грекова
…to update the literature data with the clinical features of pregnancy in multidrug-resistant tuberculosis (MRD-TB) and type 1 diabetes mellitus (T1DM) comorbidities based on an example from own clinical experience. A clinical case of pregnancy course in MRD-TB and T1DM comorbidit…
Jones AJ, Mathad JS, Dooley KE, Eke AC
…rcular (anti-TB) agents and antiretroviral therapy (ART) in pregnancy. Recent findings This review discusses the currently available evidence on the use of anti-TB agents in pregnant PLWH on ART. Pharmacokinetic and safety studies of anti-TB agents during pregnancy and postpartum…
О. М. Raznatovska, О.S. Shalmin, V.G. Syusyuka, Yu. V. Mironchuk, A.V. Fedorec, et al.
The own observation of pregnancy and tuberculosis after COVID-19 in a patient who was treated in the pulmonary tuberculosis department N 2 of the Zaporizhia Regional Phthisiopulmonology Clinical Medical Diagnostic Center is presented. According to the presented clinical case, a w…
Nishitha Gandavaram, M Rajalekshmi
Tuberculosis (TB) during pregnancy, especially with central nervous system (CNS) involvement, poses significant risks to maternal and fetal health. This case report explores the diagnostic and therapeutic challenges of managing new-onset seizures in a pregnant patient with CNS-TB…
О. М. Raznatovska, О.S. Shalmin
…ency of diagnosing a specific process in pregnant women and pregnancy in women with tuberculosis is almost the same. Today, against this background, the treatment of chemoresistant tuberculosis (CR-TB) in pregnant women remains controversial.The purpose. To conduct a review of cu…
Garay-Aguilar NV, Reynoso-Rosales LR, Llamo-Vilcherrez AP, Toro-Huamanchumo CJ
…10 causes of death worldwide. The significance of TB during pregnancy lies in its symptoms, which can be mistaken for physiological changes associated with pregnancy. This confusion can lead to maternal-perinatal complications. Objective To evaluate the association between pulmon…
Litao Guo, Xiaoling Wu, Lin Cao
…cribe the clinical characteristics of MPTB after IVF-ET and pregnancy outcomes to provide reference for early diagnosis and treatment. **METHODS:** Clinical data from patients who developed MPTB after IVF-ET from January 2018-December 2021 were retrospectively and statistically …
Chu Y, Chen Y, Yao W, Wang L, Zhang B, et al.
…lity, and whether LTBI would affect the ovarian reserve and pregnancy outcome of infertile women undergoing intrauterine insemination (IUI) is still unknown. A single-center, retrospective, cohort study was designed that included infertile women undergoing IUI at the Department o…
Simpson G, Philip M, Vogel JP, Scoullar MJL, Graham SM, et al.
For women infected with Mycobacterium tuberculosis, pregnancy is associated with an increased risk of developing or worsening TB disease. TB in pregnancy increases the risk of adverse maternal and neonatal outcomes, however the detection of TB in pregnancy is challenging. We aime…
Mendiratta V, Yadav A
Pregnancy with systemic lupus erythematosus (SLE) requires special attention in view of the enhanced risks to the fetus and the aggravation of SLE during pregnancy. Human immunodeficiency virus infection can further complicate the course of pregnancy as well as the outcome. We pr…
Liu K, Zhang X, Ma X, Jia X, Zhao X, et al.
…though female genital tuberculosis may lead to infertility, pregnancy is still possible, especially through in vitro fertilization (IVF). In this eventuality, even latent tuberculosis (TB) infection is prone to reactivate. Because some of the symptoms of TB overlap with those of …