Showing 76–100 of 200 documents
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Tian Y, Chen Y
Background Stroke is a lethal complication of polyarteritis in children. Takayasu arteritis is a rare disease with an unknown etiology and is known to mainly affect young women. In this report, we present the case of a Chinese boy diagnosed with TA results in stroke, originally p…
Sayyahfar S, Davoodzadeh F, Hoseini R, Rahimzadeh N, Otukesh H
IGRA has been approved as an alternative in vitro test to diagnose Mycobacterium TB infection. This study aimed to assess the diagnostic value of TST in comparison with QFT assay to detect LTBI among Iranian children candidate for renal transplantation. This cross-sectional study…
Phaisal W, Jantarabenjakul W, Wacharachaisurapol N, Tawan M, Puthanakit T, et al.
Objectives This study investigated the steady-state pharmacokinetic profiles of 3-month weekly rifapentine plus isoniazid (3HP) in children with latent tuberculosisinfection (LTBI). We also assessed other factors, including tablet integrity, food, and pharmacogenetics. Methods Du…
Carvalho ACC, da Silva Martins P, Cardoso CAA, Miceli AL, Martire T, et al.
Aim To evaluate the clinical characteristics, diagnostic approach, and treatment outcomes of tuberculosis (TB) in children living in a high-burden metropolitan area. Methods This was a retrospective study, based on a medical chart review, involving children under 15 years old tre…
İlteriş Türk, Mehmet Çetin, Nesrin Gürçay, Neriman Sarı, Şeref Özkara
In childhood sarcomas, the lung is one of the most common organs where metastasis occurs. Immunosuppression caused by antineoplastic treatments for primary cancer may facilitate the reactivation of latent tuberculosis (TB) infection, which can mimic cancer metastasis. The thought…
İlteriş Türk, Mehmet Çetin, Nesrin Gürçay, Neriman Sarı, Şeref Özkara, et al.
In childhood sarcomas, the lung is one of the most common organs where metastasis occurs. Immunosuppression caused by antineoplastic treatments for primary cancer may facilitate the reactivation of latent tuberculosis (TB) infection, which can mimic cancer metastasis. The thought…
Unki P, Kondekar S, Morkhade K, Rathi SP, Rathi PM
Tuberculosis (TB) is one of the main contributors to global mortality and morbidity. Prevalence of TB is more in developing countries. It is one of the airborne diseases that has always been a major health problem. It is caused by organisms of the Mycobacterium tuberculosis (MTB)…
Magdalena D, Michal S, Marta S, Magdalena KP, Anna P, et al.
Profound tuberculosis (TB)-induced metabolic changes reflected in the blood metabolomic profile may provide an opportunity to identify specific markers of Mycobacterium tuberculosis infection. Using targeted liquid chromatography tandem mass spectrometry, we compared the levels o…
Francesca Montagnani, PhD, MD
…in the diagnosis of tuberculosis (TB - active or latent) in pediatric subjects (0 and 17 year)s recently exposed to infection (indicated as "contacts") or with clinical suspicion of active TB, and to compare the results obtained with those of the TuberculinSkin Test (TST; gold st…
Prasanta Kumar Das, Somtirtha B Ganguly, Bodhisatya Mandal
…of an effective control. India accounts for 6% incidence of pediatric TB cases in a population that has 40% as estimated latent TB cases. Gastric Lavage /aspirates were taken under study for pediatric patients as key population. Collection of sputum samples from the pediatric pat…
Ollier V, Antoun F, Thouvenin G, Faye A, Kone-Paut I, et al.
…evaluate the percentage of potentially preventable cases of pediatric TB stemming from inadequate screening. The data gathered on children aged 0 to 10 years, who were evaluated by the Paris Center for TB Control (CLAT75) between January 2009 and December 2013, were extracted and…
Chen L, Hua J, He X
… subtypes as biomarkers for distinguishing ATB from LTBI in pediatric patients. Method The expression profiles of cuproptosis regulators and immune characteristics in pediatric patients with ATB and LTBI were analyzed based on GSE39939 downloaded from the Gene Expression Omnibus.…
Universidad Peruana Cayetano Heredia
… in paraguayan patients infected with Chikungunya virus 11. Pediatric STAT3 Hyper-IgE Syndrome: A case series 12. Activated PI3K Delta Syndrome in a Pediatric Patient: A Case Report on Diagnosis and Management 13. Temporal study of inflammation and its relation to the progression…
T. A. Sevostyanova, L. F. Shamuratova, O. V. Zubova, L. V. Slogotskaya, M. P. Korchagin
…f a mass screening study for tuberculosis prevalence in the pediatric population of a metropolis city were analyzed. The study was conducted during 2019–2021 in Moscow using the Mantoux skin test with 2 TE PPD-L and a skin test with a recombinant tuberculosis allergen (RTA), as w…
Yalçın Kara, Mahmut Can Kızıl, Merve İşeri Nepesov, Aslı Kavaz Tufan, Nuran Çetin, et al.
…imed to investigate the risk of tuberculosis development in pediatric patients using anti-TNF drugs. Method: One hundred and fifteen pediatric cases who were followed up in Eskişehir Osmangazi University Faculty of Medicine, Department of Pediatrics between January 2011 and Decem…
Eva Maria Guix-Comellas, Professor
…in the outpatient tuberculosis (TB) Unit of a tertiary-care pediatric center in Catalonia (Northeast Spain), which is a referral center for pediatric TB (Hospital Sant Joan de Déu) in the Southern Barcelona Health Care Region (Regió Sanitària Barcelona Sud) (1,346,000 inhabitants…
Amanda de O E Moreira, Lêda Maria S Azevedo Neta, Márcia Pietroluongo, Ana Paula Dos S Matos, Beatriz B Correa, et al.
: Pediatric drug administration is hindered by difficulties in swallowing conventional medications and the unpalatable taste of many drugs. Among diseases highlighting the need for improved pediatric delivery, tuberculosis (TB) stands out. One form of the disease is latent TB inf…
Per Bjorkman, MD, PhD
… informed about symptoms and signs that may indicate active pediatric TB. Study infant caretakers are instructed to contact the study site EPI clinic directly if the infants develop such symptoms for unscheduled study visits (in order to assess incident active TB during follow-up…
Ariadna Guinea Lagunes, Marta Ponce, E Contreras Aviles, G. Prado, Ruy Perez, et al.
…osa-Morros MT, Fortuny C, Noguera-Julian A. Tuberculosis in pediatric patients treated with anti-TNFα drugs: a cohort study. Pediatr Rheumatol Online J. 2015 Dec 3;13:54. doi: 10.1186/s12969-015-0054-4. PMID: 26635208; PMCID: PMC4669612. Calzada-Hernández J, Anton J, Martín de Ca…
Christopher Schmitt, Jocelyn Castro, Jessica Frelinger, Larry Yin
… >90% of patients, headache in 80.9% and rash in 47.5%.4 In pediatric patients, abdominal pain, diarrhea and sore throat are common manifestations. Myalgias, cough, conjunctivitis and back pain were less common. Other common symptoms include malaise, chills, myalgia, anorexia, ba…
Olga Bilogortseva, Ya. I. Dotsenko, Oksana Sivachenko, L. V. Arefyeva, V. V. Gorbenko, et al.
…mination, preventive treatment and dynamic observation by a pediatric phthisiatrician in order to prevent the progression of LTBI into active tuberculosis. In conditions of quarantine and limited access of patients to medical services, the proposed model for predicting the risk o…
A A Amaral Ibiapina Parente, L De Melo Lima, R Baroni Aurílio, A Rodrigues Fonseca, F Sztajnbok, et al.
… are few studies about TB and latent tuberculosis (LTBI) in pediatric subjects with those diseases. Objectives:Describe subjects with rheumatic diseases and diagnosis of TB or LTBI in a pediatric pulmonology service. Methods:Descriptive, observational and sectional study wit…
Jeffrey I. Campbell, Mary Tabatneck, Grete E. Wilt, Grete E. Wilt, Mingwei Sun, et al.
Abstract Background Location and type of clinic where pediatric latent TB infection (LTBI) care is provided are associated with treatment completion and retention in care. Prior research has not evaluated joint clinical management occurring between care settings. Understanding ca…
Holly Rawizza, MD, MPH
…g two-way PK of short-course LTBI treatment in a vulnerable pediatric population. This study is a prospective, single-arm, open-label, intensive and sparse pharmacokinetic (PK) and safety study to evaluate steady-state dolutegravir (DTG) and rifapentine (RPT) concentrations amon…
Saborni Dey, Siddarath Kumar, Vivek Tyagi, Venkata Sai Charan
…etermine the sensitivity and specificity of Mantoux test in pediatric patients for the diagnosis of TB. It also assists to study various presentations of TB in Mantoux test-positive patients. Materials and Methods: From August 2022 to January 2023, a single tertiary care facility…