Showing 76–100 of 200 documents
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Thinley Dorji, Karchung Tshering, Lila Adhikari, Thinley Jamtsho, Pavitra Bhujel, et al.
Abstract Despite decreasing overall tuberculosis notifications, the proportion of multidrug-resistant tuberculosis (MDR-TB) cases are increasing in Bhutan. While most MDR-TB cases are diagnosed among patients in the bordering districts and the capital, current diagnostic tests ar…
Verza M, Scheffer MC, Salvato RS, Schorner MA, Barazzetti FH, et al.
Mycobacterium tuberculosis (M.tb), the pathogen responsible for tuberculosis (TB) poses as the major cause of death among infectious diseases. The knowledge about the molecular diversity of M.tb enables the implementation of more effective surveillance and control measures and, n…
Z. Koné, Thomas Daix, L. Yéo, K. Samaké, P Kouassi, et al.
Objectives: Multidrug-resistant tuberculosis (MDR-TB) remains a public health problem in developing countries. In children and adolescents, very few data are available in the literature on this pathology. This study aims to describe the epidemiological and clinical characteristic…
K. Gzhesik, K. Korominas, A. Nemchyk, L. A. Hryshchuk, Yu. Valetskiy
The problem of detection and treatment of tuberculosis, especially multidrug-resistant, remains relevant in the world. This article analyzes the situation with tuberculosis in Poland and Ukraine in modern conditions. The joint work of Polish and Ukrainian specialists is presented…
И. Т. Русев, А. А. Кузин, E. Malíková, К. В. Козлов, К. В. Жданов, et al.
More than 1,7 million people, 770 thousand people from HIV infection, died from tuberculosis worldwide in 2018. In accordance with the United Nations Sustainable Development Goals and the World Health Organization’s strategy to fight tuberculosis, all countries need to reduce the…
O.B. Pikas, M.A. Semeniuk
The analysis of professional publications regarding the clinical and epidemiological features of tuberculosis in contemporary conditions was conducted. Literature review indicates that tuberculosis remains a pressing issue in Ukraine, particularly amidst the conditions of militar…
Abdul Massiah Metry, Issa Al Salmi, Seif Al-Abri, Faisal Al Ismaili, Yaqoub Al Mahrouqi, et al.
…transplant (KTX) patients have higher rates. We studied the epidemiology and outcome of TB in patients with kidney dysfunction in a tertiary care hospital in the past decade. We examined data of patients with TB with and without kidney dysfunction from 2006 to 2015 through an ele…
Ngom N F, Mbaye B R, N.Z. Rybina N.A., Thiam K., Faye F A, et al.
Aims: this study aimed to investigate the epidemiological, clinical, and evolutionary aspects of pulmonary tuberculosis in the elderly and to determine the factors associated with death. 
 Study Design: This was an exhaustive, descriptive, and analytical retrospective study.…
А. V. Kukurika, E. I. Yourovskaya, V. A. Lyakhimets
The epidemiological significance of combined forms of especially dangerous infections has not been studied enough, unlike mono-infections. Currently, there is a tendency towards an increase in the incidence of multidrug-resistant tuberculosis. The formation of severe forms of the…
Anjana Singh, Ved Prakash, Ravi Kant
Introduction: Multi drug resistant-TB (MDR-TB) threatens global TB control and is a major public health concern in several countries. The present study was undertaken to detect the epidemiological correlates and treatment outcomes among patients with MDR-TB previously or currentl…
Ayôla Akim ADEGNIKA
…nt challenge in Central Africa. Understanding the molecular epidemiology and genotypic characteristics of MDR-TB strains is crucial for effective control measures. This is highlighted by the emergence of mutations encoding resistance to bed aquiline and quinolones which may impac…
Shibabaw A, Gelaw B, Ghanem M, Legall N, Schooley AM, et al.
… MDR-TB in Ethiopia. Objective To investigate the molecular epidemiology and transmission dynamics of MDR-TB strains using whole genome sequence (WGS) in the Amhara region. Methods Forty-five MDR-TB clinical isolates from Amhara region were collected between 2016 and 2018, and ch…
Zhu J, Haanpera M, Mentula S, Vapalahti O, Soini H, et al.
Background Data on the molecular epidemiology and transmission of drug-resistant Mycobacterium tuberculosis (MTB) in low-incidence settings with immigration from high-incidence settings is limited. Method We included 115 drug-resistant (DR) MTB isolates with whole-genome sequenci…
Huma Haider
… This rapid literature review highlights key aspects of the epidemiology of malaria, HIV and TB in Zimbabwe and challenges in prevention, detection and treatment; and surveys select interventions that seek to address these challenges. It has not been possible to provide a compreh…
Duan Q, Zhang Z, Tian D, Zhou M, Hu Y, et al.
Abstract How multidrug-resistant tuberculosis (MDR-TB) spreads and expands in Wuhan population is not clear. The study aimed to determine the transmission patterns of MDR-TB in Wuhan city, China, including 149 patients with MDR-TB.Tuberculosis isolates were genotyped by deletion-…
Malabad JCM, Ang CF, Palabrica FAR, Cajucom MAM, Gloriani NG, et al.
…articularly among people living with HIV (PLHIV). Molecular epidemiology provides information on prevalent genotypes of Mycobacterium tuberculosis and disease transmission dynamics, which aid in TB control. Identification of mutations that confer drug resistance is essential for …
Gautam SS, Mac Aogáin M, Cooley LA, Haug G, Fyfe JA, et al.
…sis of MTBC isolates from Tasmania to better understand the epidemiology of TB in the state. Methods Whole-genome sequencing was performed on cultured isolates of MTBC collected from 2014-2016. Single-locus variant analysis was applied to determine the phylogeny of the isolates a…
Rahman SMM, Rahman A, Nasrin R, Ather MF, Ferdous SS, et al.
…h, a major gap exists in our understanding of the molecular epidemiology of the MDR-TB isolates in Bangladesh. In our study, we characterized and classified the MDR-TB isolates circulating in Bangladesh and investigated their mode of transmission. Our results demonstrated that th…
Karnappa Bhangari, Basavaraj Sangolli
Epidemiological and clinical profile of multi drug resistant tuberculosis cases in Chitradurga district - IJIRM- Print ISSN No: - 2581-4214 Online ISSN No:- 2581-4222 Article DOI No:- 10.18231/j.ijirm.2020.035, IP Indian Journal of Immunology and Respiratory Medicine-IP Indian J …
Merker M, Egbe NF, Ngangue YR, Vuchas C, Kohl TA, et al.
Background Determining factors affecting the transmission of rifampicin (RR) and multidrug-resistant (MDR) Mycobacterium tuberculosis complex strains under standardized tuberculosis (TB) treatment is key to control TB and prevent the evolution of drug resistance. Methods We combi…
Tilahun M, Ameni G, Desta K, Zewude A, Yamuah L, et al.
… We investigated the drug sensitivity pattern and molecular epidemiology of mycobacterial strains isolated from pulmonary TB patients in and around Ambo town in Oromia Region, Central Ethiopia. Methods A cross-sectional study was conducted involving 105 consecutive new smear posi…
Krishna Mohan PhD, Md. Aftab Alam PhD, Ranjana Patnaik PhD, Khalid Umer Khayyam, Salik Umer Khayyam MBBS
Objective: To study the clinical-epidemiological profile and treatment outcomes of tuberculosis patients diagnosed at two designated microscopy centres (DMCs) in New Delhi, India. Methods: Data was collected from the available treatment records as well as from the online notifica…
Yang Deng, Xin He, Cise Bibu, Yi-Xuan Ren, Yong Fang, et al.
…ded a critically important investigation into the molecular epidemiology of drug-resistant tuberculosis in Meigu County, a remote and high-burden region in Sichuan Province, China. By combining DNA microarray chip technology and whole-genome sequencing, the researchers characteri…
Tuberculosis (TB) remains a significant public health challenge in Pakistan, exacerbated by socioeconomic disparities, healthcare system limitations, and emerging drug-resistant strains.This study investigates the epidemiological trends, socio-clinical determinants, and intervent…
Ariadna Petronela Fildan, Beatrice Mahler, Enis Beitula, Ioan Anton Arghir, Ioana Gherghișan, et al.
Aim: To describe the clinical and epidemiological features of patients who developed simultaneously lung cancer (LC) and pulmonary tuberculosis (PTB). Material and methods: Retrospective study of the medical records of patients diagnosed with LC and PTB at the Constanta Pneumopht…